Monaco swept into the Champions League quarter-finals and left Manchester City to pick up the pieces of another failed European campaign after a 3-1 victory on Wednesday sent them through on away goals.
A summary of Sunday's action in Serie A and La Liga.
Yet Milan's defensive frailty was punished when Konstantinos Fortounis scored from the penalty spot in the 81st minute to give his side the win that left them second in Group F on 10 points.
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Watford equalised seconds before halftime through Abdoulaye Doucoure and in a rampant spell of attacking football went ahead four minutes after the break when Roberto Pereyra tapped home a Richarlison cross.
Daryl Janmaat, Gerard Deulofeu and Roberto Pereyra all scored late on in response to Eden Hazard dragging Chelsea back into the game with a curler in the 82nd minute after Tiemoue Bakayoko was sent off for a second booking on the half-hour.
Mbappe, 18, has scored 18 goals in his last 18 competitive games, including three in the 6-3 aggregate win over Borussia Dortmund in the last eight.
Chelsea a 1-0 win over Manchester United in a compelling Premier League clash on Sunday
Images from the football matches played across Europe on Tuesday.
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Images from the English Premier League London derby played between Arsenal and Chelsea at the Emirates on Wednesday
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Karim Benzema fired Real Madrid to a 1-0 win in the city derby against Atletico Madrid on Saturday which underlined Real's La Liga title credentials. Bayern Munich scored three goals in the opening 26 minutes to defeat Mainz 05 3-1 away on Saturday and go two points clear at the top of the Bundesliga with their sixth straight win.
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Soccer highlights from across the globe.
United are 16th in the standings with a game in hand heading into the international break.
Angel Di Maria delivered a near-perfect performance, scoring two and setting up another as runaway leaders Paris St Germain beat 10-man Olympique de Marseille 3-1 at home on Sunday.
Ibrahimovic was forced off with a muscle problem with 11 minutes remaining, and the Swede was pictured sitting on the bench with an ice pack strapped to the back of his left leg.
Substitute Jesse Lingard struck twice in the second half as Manchester United fought back from 2-0 down to earn a 2-2 Premier League draw with Burnley at Old Trafford on Tuesday.
Images from the English Premier League matches played on Saturday
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A fortunate 85th-minute goal from Brazilian Willian earned Premier League champions Chelsea a 1-1 draw at Liverpool on Saturday after Mohamed Salah's 15th goal of the season looked to have given the hosts the three points.
News of all that's transpired on and off the football field on Saturday
A toothless and haggard Real Madrid slumped to a humiliating 10th Liga defeat of the season on Sunday as they lost 1-0 at struggling neighbours Rayo Vallecano.
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Images from the English Premier League matches played on Tuesday.
Bayern Munich put upstarts RB Leipzig firmly in their place by sweeping to an emphatic 3-0 home win, with all the goals coming in the first half, in a disappointingly one-sided top-of-the-table Bundesliga clash on Wednesday.
Barcelona closed in on the La Liga title after beating 10-man Atletico Madrid 2-0 in Saturday's top-of-the-table showdown at the Nou Camp as late strikes by Luis Suarez and Lionel Messi gave the Catalans an 11-point lead at the top of the table.
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Chelsea found no chink in Everton's defensive armour as the Premier League champions were held to a frustrating 0-0 draw at Goodison Park on Saturday.
A summary of all the Champions League matches played across Europe on Tuesday