Inspired by 24-year-old playmaker Shoya Nakajima and forward Takumi Minamino, who finished the night with a brace, Japan stunned Oscar Tabarez's side, who are ranked fifth in the world.
Real Madrid keeper Iker Casillas believes the European champions have a side with the potential to be one of the all-time greats and it will be with likely trepidation that an off-colour Liverpool visit the Bernabeu on Tuesday.
The consequences of failure are nowhere more devastating than at a World Cup, where two previous finals and five semi-finals have been decided by the gut-wrenching lottery of penalties.
Defeat always seemed likely for West Brom, who are bottom of the Premier League and sacked their chairman and chief-executive on Tuesday.
Napoli went down 3-1 at home to RB Leipzig, Arsenal and AC Milan enjoyed comfortable away wins, and Borussia Dortmund's Michy Batshuayi scored twice to secure a 3-2 victory in Europa League last 32, first leg action
Brazil need solutions after coming unstuck against Swiss
Cristiano Ronaldo helped Juventus continue their unbeaten start to the Serie A season with a comfortable 2-0 home victory over struggling SPAL on Saturday.
Belgium became the first European team to qualify for next year's World Cup when a Romelu Lukaku header gave them a 2-1 win away to Greece on Sunday with the goals coming in a five-minute second-half spell.
Real Madrid's teenage Brazilian duo Vinicius Junior and Rodrygo Goes sent them top of La Liga as both scored in a 2-0 win over Osasuna on Wednesday.
Rediff.com brings these and other big news from the sporting world, encapsulated in this photo feature...
Cristiano Ronaldo may have played his last game for Real Madrid after winning a fourth Champions League crown with the Spanish side in a 3-1 victory over Liverpool on Saturday, saying he would soon make an announcement on his future.
Here, Reuters Sport highlights five reasons why last season's double winners have collapsed.
The Indo-Belarussian pair beat Yevgeny Kafelnikov and Gustav Kuerten in the second round of the ATP Masters.
With 11 million likes, Beyonce's maternity shoot pic tops the list of most-liked pics of 2017.
Lionel Messi marked his retirement about face with a goal to give 10-man Argentina a 1-0 win over Uruguay on Thursday that lifted them to the top of the South American qualifying group for the 2018 World Cup finals in Russia.
Cristiano Ronaldo's agent has defended the FIFA Ballon d'Or winner after he was criticised for throwing a lavish 30th birthday party on Saturday hours after Real Madrid's 4-0 La Liga drubbing at Atletico.
Defending champions India missed out on the bronze medal after going down 5-6 via tie-breaker to Spain
Holders Real Madrid came from a goal down to snatch a precious 2-1 victory at wasteful Bayern Munich on Wednesday and carry a considerable advantage into their Champions League semi-final second leg in Spain.
From May 26 onwards, the US Citizenship and Immigration Services will begin accepting applications for work visas from H-IB spouses, reports Aziz Haniffa/Rediff.com.
Bravo stopped Portugal's first three spot kicks from Ricardo Quaresma, Joao Moutinho and Nani while Chile converted their first three to win the clash of South American and European champions.
Hollywood takes Toronto by storm!
Celebs have taken a liking to wearing outfits that are fit for a sleepover.
It was Paes's fourth title this year, having won in Halle, Gastaad and Canada.
AC Milan, Villarreal and Nice reached the knockout stage of the Europa League after posting wins on Thursday in the penultimate round of the group stage.
Carlos Bacca's first-half goal was enough to give Colombia a 1-0 victory over the United States in the third-place playoff at the Centenary Copa America in Arizona on Saturday.
Here are five talking points from the weekend's action:
A summary of sports events and sports persons, who made news on Wednesday
The Belgian is emerging from months of struggle against a debilitating virus.
'There is no advantage. I always prefer to play in front of supporters even away from home because that's what football is all about, but that's the situation we face'
Bengaluru FC had a satisfying Indian Super League debut as they beat Mumbai City FC 2-0 in their opening encounter with Spaniard Eduardo Martin Garcia and skipper Sunil Chhetri on target.
The third seeded pair registered a comfortable 6-3, 6-4 win against Karsten Braasch of Germany and Sargis Sargsian of Armenia.
News of all that's transpired on and off the football field
The 2019 Formula One world championship starts on March 17 with 21 races in a season that ends later than any since 1963.
Lionel Messi came off the bench to preserve Barcelona's unbeaten run in La Liga with a sensational late equaliser in a thrilling 2-2 draw at Sevilla on Saturday as the runaway leaders came back from two goals down in the space of a minute.
The Indo-Belarussian pair beat the Argentine duo of Gaston Etlis and Martin Rodriguez to keep their hopes of qualifying for the semis of the ATP Masters.