Since winning 2-1 at home to Wolfsburg in September, United have scored only twice in three Champions League games. In the Premier League the record is five goals in the last six games.
Juergen Klopp's side remain seventh, six points behind the Champions League places, after only their second defeat in the 12 games since the German took over in October
News of all that's transpired on and off the football field
On a night of close finishes in all five first-leg playoff games, the 21-year-old Dutch winger opened his United account with a memorable performance in the famous number seven shirt previously worn by George Best, Eric Cantona and David Beckham.
AC Milan chief executive Adriano Galliani is to quit after 27 years at the Serie A club, he told the ANSA news agency on Friday.
Ajax Amsterdam registered a 4-1 win at De Graafschap, their first title since 2014 and a record-extending 34th overall completed the double after they won the KNVB Cup earlier this month.
News of all that's transpired on and off the football field
Wayne Rooney's Everton homecoming ended in a 1-0 win over Slovak side Ruzomberok with the former Manchester United striker having a quiet return to Goodison Park in the Europa League, third qualifying round, first-leg on Thursday.
Monaco's firepower was far too hot to handle for Olympique de Marseille as the Principality side moved top of the French Ligue 1 standings with a 4-0 home win on Saturday.
Napoli's Marek Hamsik enjoyed a memorable return to his former club Slovan Bratislava, scoring one and creating another, in a 2-0 victory on Thursday as the Italians joined five others who made it two wins from two in the Europa League group stage.
Sevilla's love affair with the Europa League was immediately rekindled as last season's champions and three-time winners began this year's group stage with a 2-0 home victory over Feyenoord on Thursday.
Jamie Vardy equalled the English Premier League record by scoring for a 10th successive match as his Leicester City side went top after winning 3-0 at Newcastle United while champions Chelsea ended their slump with a 1-0 win over Norwich City on Saturday.
Christian Eriksen kept Tottenham Hotspur's hopes of completing a remarkable salvage job and reaching the last 16 of the Champions League alive with a late winner in his side's 1-0 victory over Inter Milan at Wembley on Wednesday.
Manchester United's hopes of salvaging their season in the Europa League suffered a stinging setback when they lost 2-1 at Danish side Midtjylland in the first leg of their last-32 clash on Thursday.
The last-16 knock-out round kicks-off this week with Chelsea visiting Paris on Tuesday; Zidane to coach Real Madrid as manager in his first match in Europe
Holders Sevilla maintained their Europa League challenge with a 1-0 win over Rijeka in a winner-takes-all clash on Thursday.
Despite a splurge of summer spending of more than 500 million pounds and counting, it was a free transfer from France who provided one of the standout moments of the Premier League's big kickoff.
Zlatan Ibrahimovic bagging four goals, while Juventus and Bayern Munich preserved their leads and FA Cup holders Arsenal were dumped out of the competition.
Atletico Madrid sealed top spot in Champions League Group D after second half goals from Frenchmen Kevin Gameiro and Antoine Griezmann but Napoli were held to a 0-0 Champions League draw at home by Dynamo Kiev.
Goals from Jan Vertonghen and Jermain Defoe left Tottenham Hotspur on the cusp of the Europa League knockout stages as four other clubs maintained perfect starts on Thursday.
Barcelona's rampant trio of Neymar, Luis Suarez and Lionel Messi all found the net at the weekend and unsung Leicester City found themselves in the record books when their England striker Jamie Vardy scored for the 11th straight game.
News of Van Gaal's impending departure from the club leaked out minutes after Saturday's 2-1 extra-time victory over Palace and, following relentless media speculation and a day of negotiations, it was confirmed by both sides on Monday evening.
Rediff.com takes a look at a few other players who shunned champion sides for mediocre clubs in the Premier League.
Barcelona look well set to wrap up the La Liga title.
Chelsea moved within touching distance of a first Premier League title in five years with a 1-0 win over Manchester United while Lionel Messi reached a landmark with his 400th career goal for La Liga leaders Barcelona.
VfL Wolfsburg reached the Champions League last 16 and dealt a knockout blow to Manchester United with a 3-2 victory to claim top spot in Group B and condemn their opponents to the Europa League on Tuesday.
Photos from the Champions League matches played across Europe on Tuesday
Sweden beat Italy 1-0 to gain the upperhand after their World Cup playoff first leg on a chilly night, while a young England side held Germany goalless and Belgium drew 3-3 with Mexico despite Romelu Lukaku's double but France eased to a 2-0 victory against Wales.
Cristiano Ronaldo bagged his first five-goal haul in Real Madrid's 9-1 hammering of Granada while title-chasing Bayern Munich and Chelsea won again in Germany and England.
La Liga leaders Real Madrid were thumped 4-0 away by city rivals Atletico Madrid to open up the Spanish title race, while Chelsea strengthened their hold on top spot in the English Premier League after a 2-1 win at Aston Villa.
Inter Milan staged a late smash-and-grab raid as goals by Mauro Icardi and Matias Vecino secured a 2-1 home win over Tottenham Hotspur in their Champions League Group B opener on Tuesday.
Real Sociedad midfielder Carlos Vela was called up by Mexico for November tour friendlies on Tuesday after turning his back on his country since March 2011.
News of all that's transpired on and off the football field
Cristiano Ronaldo set a record for goals scored in the group stage of the Champions League of 11 when he netted four against Malmo in Group A on Tuesday.
Here is the round-up of all the football action across Europe on the weekend
Ahead of the UEFA Champions League proper, which kicks-off next month, Bikash Mohapatra/Rediff.com tells football fans what to expect in this year's competition.
Photos from the 2018 World Cup qualifiers played on Tuesday
Images from the Europa League matches played on Thursday
Robert Lewandowski scored a brilliant free kick to give Bayern Munich a 1-0 win over Atletico Madrid in their last Champions League Group D outing on Tuesday, ending the 100 percent record of their opponents. The Poland international curled the ball over the wall and into the corner of the net in the 28th minute but the goal had no impact on the final standings with Atletico guaranteed top spot and Bayern in second place.
Sweden striker Zlatan Ibrahimovic crowned a triumphant homecoming with a second-half goal as Paris St Germain crushed Malmo 5-0 on Wednesday to book a place in the last 16 of the Champions League.