Messi ran amok at Wembley Stadium, slicing Spurs apart with incisive passes from deep, such as the one that allowed Philippe Coutinho to open the scoring, and was as dangerous as ever in front of goal, firing in the Catalan side's final two goals to end their winless run of three games.
Champions Liverpool suffered a shock 1-0 defeat to lowly Burnley on Thursday, ending their 68 match unbeaten home record in the Premier League as their title defence continued to fade.
Images from the English Premier League matches played on Saturday.
'It's a prize that's called The Best and the guy who is, for us, the best player in the world wasn't there.'
Salah joined Chelsea under Mourinho in 2014 but failed to establish himself at Stamford Bride and was loaned out to Fiorentina and Roma before a permanent move to the Stadio Olimpico outfit in 2016.
Kane began the night level on 19 goals with Liverpool's Mohamed Salah in the race for the Golden Boot.
IMAGES from Premier League matches played on Sunday.
City are two points behind leaders Liverpool, but have a game in hand
Goalkeeper Alisson Becker scored a stunning header in the fifth minute of stoppage-time as Liverpool snatched a 2-1 victory at the death against relegated West Bromwich Albion at The Hawthorns on Sunday.
Liverpool's Egyptian forward Mohamed Salah scored his 29th Premier League goal six minutes from time to secure a 2-1 win at Crystal Palace that took them up to provisional second spot in the table on Saturday.
Liverpool won the Super Cup 5-4 on penalties against Chelsea
Juergen Klopp's side returned to English Premier League action on Friday with a hunger and desire that suggested they have spent the close-season break chomping at the bit to get back on the field.
Russia is the lowest FIFA ranked side at the event, but two games in they are top of their group with six points and are poised to qualify for the next stage.
IMAGES from the English Premier League matches played on Sunday
Muslim soccer fans visiting Russia for the World Cup celebrated the end of the fasting month of Ramadan on Friday, with Egyptian fans hoping the festival would bring their national team good luck in a match with Uruguay later in the day.
Barcelona were held to a frustrating 0-0 draw at Olympique Lyonnais in their Champions League last-16 first leg on Tuesday as both sides remained unbeaten in this season's competition.
Alexander-Arnold, seeing the Spanish club's defenders still getting organised, feigned to walk away from the corner before racing back to whip the ball to the unmarked Divock Origi, who clipped it past Marc-Andre ter Stegen.
The reigning champions have won 53 and drawn 11 of those 64 games, scoring 169 goals and conceding 42 for a total of 170 points.
Arsenal suffered another painful Premier League defeat as Swansea City capitalised on some glaring errors to win 3-1 on Tuesday, boosting their survival hopes and denting the visitors' top four chances.
What makes Juergen Klopp's side such an unstoppable force?
Images from the English Premier League matches played on Saturday
Images from the UEFA Champions League matches played on Tuesday.
Images from the UEFA Champions League matches played on Tuesday night.
Images from the English Premier League matches played on Saturday
Last term, stung by City's woeful performance the previous season in a 3-0 Champions League loss at Anfield, Guardiola adopted a cautious approach in a goalless draw.
Liverpool boss Juergen Klopp has beaten Manchester United only twice in his career and never at Old Trafford -- his worst record against any Premier League side.
Champions Liverpool were ripped apart 7-2 at Aston Villa and Manchester United were humiliated 6-1 at home by Tottenham Hotspur on Sunday in one of the most astonishing days of Premier League results.
Champions Juventus lost for the third time in six Serie A matches this season after goals from Lorenzo Insigne and Gonzalo Higuain secured a 2-1 home win for Napoli on Saturday.
Atalanta's Josip Ilicic and Robin Gosens scored quickfire second-half goals to give them a comfortable 2-0 win over a toothless Liverpool
"I don't know how this affects my future," Valverde said.
Leaders Liverpool faltered in the English Premier League title race for the second time in six days as they were held to a 1-1 draw at West Ham United.
English Premier League leaders Liverpool opened up a 22-point gap at the top of the table with second-half goals from Alex Oxlade-Chamberlain, Jordan Henderson and a Mohamed Salah brace giving them a 4-0 home win over Southampton. A rare double from defender Antonio Rudiger earned Chelsea a point in an entertaining 2-2 draw with third-placed Leicester City.
"I can almost assure you 100 percent that he will play, save unforeseen circumstances at the very last minute," Cuper told a news conference ahead of Friday's Group A match.
Images from Saturday's action in the Premier League.
Inspirational manager Juergen Klopp has rekindled the Anfield flame though and delivered the club's 19th top-flight title, one behind arch-rivals United's record of 20, after finishing runners-up to City in a thrilling race last season.
Real Madrid moved into the semi-finals of the Champions League after their makeshift defence held on for 0-0 second-leg draw with Liverpool at Anfield on Wednesday to complete a 3-1 aggregate win.
Liverpool went into last Sunday's Merseyside derby on the back of five wins from their previous six league games but were held to a 1-1 draw at Anfield by Everton and then to a goalless stalemate at home against West Bromwich Albion on Wednesday.
Two goals each for Roberto Firmino and Sadio Mane helped Liverpool to keep in touch with Premier League leaders Manchester City with a 4-2 win over lowly Burnley at Anfield on Sunday.
Liverpool's James Milner's converted a penalty on the stroke of half-time and Sadio Mane added a late second goal to secure a hard-fought 2-0 victory at Crystal Palace in the Premier League on Monday.
'If VAR is coming then it is a situation where you have to look again. Not to give a red card but to look again and say: 'What is that?' It was ruthless.'
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