Tottenham Hotspur climbed to third with a 3-1 win over Southampton while Chelsea hung on to fourth spot, above Arsenal on goal difference, despite a 2-1 defeat at Wolverhampton Wanderers.
Facts and figures ahead of Saturday's Champions League final between holders Real Madrid and Liverpool in Kiev:
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Liverpool romed into the Europa League final with a 3-0 win over Villarreal on another magical night at Anfield to tee up a showpiece clash with holders Sevilla who swatted away visitors Shakhtar Donetsk 3-1 on Thursday.
Reigning champions Manchester City took the lead after 24 seconds but suffered a shock 2-1 defeat at Newcastle United.
Manchester City opened up a two-point lead over their neighbours Manchester United at the top of the English Premier League on Saturday thanks to another display of scintillating brilliance in a 7-2 thrashing of Stoke City at the Etihad Stadium.
Liverpool did not reveal the transfer fee but Southampton announced it was "a new world-record for a defender" with English media reporting that it was a 75 million pounds ($100.49 million) deal.
Jose Mourinho's unbeaten Manchester United face the biggest test yet of their title credentials when they visit Liverpool at Anfield on Saturday -- a fixture that always has a little extra spice.
After Sunday's 1-3 loss to Manchester City the calls for Jose Mourinho's ouster are only going to get louder.
Arsenal manager Arsene Wenger is to stand down at the end of the season after a reign of almost 22 years that made him the most successful boss in the Premier League club's history.
Hazard's dribbling and movement, on and off the ball, constantly posed questions for the Liverpool defence and the winger, who was so central to Chelsea's title triumph last year, certainly looks back up to full speed.
Manchester City's Kompany out of Liverpool clash with calf injury
Images from the English Premier League matches played on Saturday
News of all that's transpired on and off the football field.
A summary of Sunday's Premier League matches
Liverpool belatedly kick-started their year and damaged Tottenham Hotspur's slender Premier League title hopes as Sadio Mane struck both goals in a 2-0 victory at Anfield.
Mourinho's tinkerings meant a first start of the season for midfielder Scott McTominay, playing on the right of a three-man defence, while Anthony Martial played instead of the dropped Alexis Sanchez. On this evidence, more changes may be needed when United take on Valencia in the Champions League on Tuesday.
Barcelona have been haunted by their recent failures in the Champions League and there are concerning signs for the Catalans as they prepare for Tuesday's last-16 first leg away to Olympique Lyonnais.
IMAGES from the English Premier League match played between Manchester United and Liverpool at Old Trafford on Saturday
Nigerian international Odion Ighalo scored twice as a buoyant Watford won 3-0 at home to Liverpool to consolidate seventh position in the Premier League, only one point behind the top four.
News of all that's transpired on and off the football field
Triple European champions Manchester United and their under-fire coach Louis van Gaal face a tricky task against little-known Midtjylland in the last 32 of the Europa League following Monday's draw.
Liverpool and Manchester United's globe-trotting squads must shake off the effects of international duty for one of English football's most eagerly-anticipated clashes on Saturday.
Manchester City claimed the win required to finally end Liverpool's relentless attempt to dethrone them as Premier League champions as they hit back from a goal down to crush Brighton and Hove Albion on the south coast on Sunday.
A round-up of Wednesday's night's UEFA Chmpions League matches.
Goals rained in for Manchester City and Manchester United but Juergen Klopp's first game in charge of Liverpool was solid rather than spectacular with his new side drawing 0-0 at Tottenham Hotspur in the Premier League on Saturday.
Liverpool goalkeeper Simon Mignolet saved an early penalty and James Milner's shot was deflected into his own net by Havard Nordtveit for the English Premier League side's second goal in an end-to-end match.
Chelsea need to improve a lot before they could be considered Premier League title contenders, manager Antonio Conte has said after his resurgent side beat Southampton 2-0 on Sunday.
Chelsea brought a whole new dimension to the Premier League title race when they handed Manchester City their first defeat of the season on Saturday to leave Mohamed Salah-inspired Liverpool as the new leaders.
Following is a match by match look at the English Premier League's weekend fixtures:
The Professional Footballers' Association (PFA) called for a government inquiry into racism in the English game following the match, which Chelsea won 2-0.
Liverpool's Mohamed Salah is willing to put his Champions League ambitions on the back-burner to help the Merseyside club claim their first English league crown in 29 years, the Egyptian forward has said.
Second-half goals from Willian and Diego Costa helped Chelsea ease past Hull City 2-0 on Saturday and grab their first win in four Premier League games.
Images from the English Premier League matches played on Saturday
Manchester City thrashed Southampton 6-1 to remain top of the Premier League.
Manchester City manager Manuel Pellegrini believes tiredness was behind their 3-0 defeat by Liverpool on Wednesday after a third successive Premier League loss put a hefty dent in their faltering title hopes.
'The current squad is one in transition, but they have some real talent and are showing a strong sense of togetherness' 'I expect to see them continue to grow and develop over the coming weeks and I wish them and my successor well for the rest of the season'
Images from the Champions League matches played on Tuesday
News of all that's transpired on and off the football field