The Mercedes driver's 55th career win was hard-fought and tense, however, with Ferrari's Vettel seizing the lead at the start and in the hunt all the way to the finish as the tyre strategies played out.
Danica Patrick was not the first woman to race at Indianapolis; Janet Guthrie broke the gender line in 1978, followed by Lyn St. James in 1992 and Sarah Fisher in 2000.
Mercedes' British driver Lewis Hamilton won the Brazilian Grand Prix at the Interlagos Circuit in Sao Paulo on Sunday to keep the Formula One Championship alive with one race left this season.
But for the 23-year-old Bouchard, a former world number five who has slumped to 56th in the rankings, it was another blow after her first-round exit in Indian Wells.
Lewis Hamilton became Britain's first four-times Formula One world champion on Sunday after fighting back from last place following an opening-lap collision with arch-rival Sebastian Vettel at the Mexican Grand Prix.
Roger Federer and Rafael Nadal have shared the grand slam spoils this year and it would take a hard heart not to hope for a fairy tale rematch next month of their epic 2008 Wimbledon final.
'There is a communication between Rahul Mukerjea and Sheena Bora.' 'First on the 26th. And then on the 27th and then on the 28th.' 'See the messages wherein Rahul Mukerjea tells Sheena Bora "Baba I am in the car park. Come".' 'And Sheena Bora replies to Rahul Mukerjea: "Five min bas".' 'This explains why none of the bodies matched Sheena Bora...'
Finnish team mate Kimi Raikkonen, who started on pole for the first time in nine years but lost the lead in the pitstops, made sure of a Ferrari one-two with Hamilton finishing seventh for Mercedes after starting 13th.
Lewis Hamilton was 'shocked' with the pace of Mercedes after notching a record-extending eighth pole position at the Australian Grand Prix ahead of team mate Valtteri Bottas as they thrashed their Formula One rivals in qualifying on Saturday.
Nico Rosberg stormed to his sixth pole position in a row and denied Mercedes team mate Lewis Hamilton a landmark 50th in Formula One's season-ending Abu Dhabi Grand Prix on Saturday.
Croatian Marin Cilic continued his recent run of sizzling form by overpowering John Isner 7-6(7-5), 6-3 in a late-night showdown to advance to the Delray Beach Open final against South Africa's Kevin Anderson.
Marussia's hopes of rising from the dead to race in next month's Formula One season-opener in Australia have suffered a setback after rivals rejected a proposal to let them compete with last year's car.
Lewis Hamilton celebrated his 50th Formula One victory on Sunday with a pole-to-flag U.S. Grand Prix drive that kept his title hopes alive and trimmed Mercedes team mate Nico Rosberg's lead to 26 points with three races remaining. Rosberg, who had been chasing his 10th triumph of the season, finished second on a sunny Texan afternoon with a big crowd but little drama -- even if Hamilton spent much of it worrying about reliability. The straightforward victory was Hamilton's fourth in Texas in five seasons and ended a barren stretch for the triple world champion dating back to his last win in Germany in July.
A summary of sports events and persons who made news on Thursday
Roger Federer booked his place in the ATP World Tour Finals for a record-tying 12th consecutive year when he dismissed South African Kevin Anderson 6-4, 6-4 to reach the third round of the Paris Masters on Wednesday.
Lahiri was the first Indian to ever qualify for the President's Cup and had been thoroughly looking forward to representing the International Team.
Lewis Hamilton spent the off-season crisscrossing the globe to party with A-list celebrities but Formula One's reigning champion is adamant there will be no hangover when he returns to work at this week's season-opening Australian Grand Prix.
Three rookies are set to make their race debuts and Azarbaijan will make it's Formula One debut even as Sebastian Vettel, Nico Rosberg pose to challenge odds on favourite Lewis Hamilton.
Serbia's Novak Djokovic is the top seed in the men's draw which includes five-times US Open champion and 17-times Grand Slam winner Roger Federer as seventh seed - his first time the Swiss has been placed outside the top three in a Grand Slam in over ten years.
Formula One's 2016 tyre rules, giving more choice on the selection of compounds and strategy, have left even some drivers confused.
Nico Rosberg ended the Formula One season on a winning high in Abu Dhabi on Sunday with team mate and triple world champion Lewis Hamilton following him home in a record 12th one-two finish for dominant Mercedes.
India's Anirban Lahiri got off to a flying start on his tournament-debut, firing eight birdies in a blemish-free opening round to grab a share of the lead at the PGA Tour's Career Builder Challenge in partnership with Clinton Foundation in La Quinta.
Tiger Woods remained unbeaten at this week's Presidents Cup as the United States maintained a one-point lead over the Internationals after the weather-delayed foursomes ended on Saturday morning.
Australia's Samantha Stosur failed to allay fears she could be heading for another early exit at her home Grand Slam with a scrappy performance in Hobart while a trio of big names tumbled out of the Sydney International on Monday.
Five players to watch at the Masters, which starts on Thursday at Augusta National.
'Masti was an experience. Grand Masti was a different experience and Great Grand Masti will be a different experience altogether.' Vivek Oberoi and Riteish Deshmukh discuss their latest film.
A summary of sports events and sports persons, who made news on Friday
'People ask me if I miss living a normal life, since I don't have privacy, and I tell them I don't want to have a normal life. I want people standing outside my house, I want to be loved by them. I have been fortunate enough to live like a star for 25 years and I would like to die as a star.' Shah Rukh Khan, unplugged.
A summary of sports events and sports persons, who made news on Friday
The lanky wild card kissed the Montreal court after completing a rousing 3-6, 6-4, 7-6(4) triumph as the 18-year-old became the youngest player to ever reach the quarter-finals of an ATP Masters 1000 event.
Formula One has lost another of its principals.
Roger Federer has now won all the seven finals he has contested in Cincinnati. Rediff.com takes a look at a few other events that have ensured prolific returns for the Swiss master.
The clock is ticking for some of Formula One's big name drivers, with world champions and race winners out of contract at the end of the season and a restless young generation eager to take their places.
Roger Federer got his delayed hardcourt season off to a positive start with straightforward 6-3, 7-6 (7) win over Germany's Phillip Kohlschreiber to ease into the third round of the Western and Southern Open on Tuesday.
India's Shiv Kapur battled to a two-under-par 70 for tied 13th place at the half-way stage of the US$7 million CIMB Classic on Friday, knowing that he needs to shift into high gear to emerge as a legitimate contender. The 31-year-old, who holds one Asian Tour title under his belt, carded three birdies against a lone bogey at the Kuala Lumpur Golf and Country Club's West course where his two-day aggregate of five-under-par 139 left him eight shots behind leader Keegan Bradley of the United States.
Novak Djokovic, Andy Murray, Rafael Nadal and Roger Federer all picked up third round wins at the Western and Southern Open on Thursday to set up a star-studded last eight in Cincinnati.
Claude Arpi, who spent 10 days in the Land of the Dragon, tells us how Bhutan is different from the rest of the world.
Claude Arpi, who spent 10 days in the Land of the Dragon, tells us how Bhutan is different from the rest of the world.
Jobs fails to meet expectations, writes Paloma Sharma.
'The bonhomie that once characterised the Shiv Sena and BJP was clearly missing this time. Is there a deeper divide than what was apparent?'