Manchester United continued their push for a top-four finish with a comfortable 3-0 victory at champions Leicester City on Sunday, extending their unbeaten Premier League run to 15 games.
But for third-placed Spurs, who trail leaders Manchester City and Liverpool by five points, this may prove to be a loss that leaves them with too much ground to make up.
Arsenal manager Arsene Wenger has blamed his side's poor finish as the reason behind their goalless draw against Southampton in their Premier League clash at the Emirates Stadium.
Chelsea manager Jose Mourinho believes that not having another international break until March will help his team recapture their best form after a woeful start to the season.
"After feeling strange in the second half of the Burton game in September, I underwent a series of tests," he said.
Premier League leaders Liverpool suffered 12 separate injuries this season to players that took part in last year's World Cup in Russia, compared to 27 for title rivals Manchester City, according to a report published on Wednesday.
Reigning champions Manchester City took the lead after 24 seconds but suffered a shock 2-1 defeat at Newcastle United.
Images from the EPL matches played on Saturday
'It's like now with Lamela or Vertonghen, how you sit in the chair and cry because you miss someone... But the competition does not allow you to cry. You have to move on quick. It's a bit cruel, but you have to move on and try to win the next game'
Goals from Rodri and Kevin De Bruyne secured a comfortable win at the Etihad
'I'm probably one of the only ones that disagrees, for the simple fact that we only had three games that we were below standard.'
Rediff.com encapsulates all the sporting action from the past week in this eye-catching photo feature.
Arsenal's new manager Unai Emery faces a baptism of fire after the Gunners were handed an opening day fixture at home to Premier League champions Manchester City.
Images from the English Premier League matches played on Sunday
Talks have been continuing between the FA, Premier League and Football League regarding the proposal as they look at the possibility of bringing their fixture schedule more in line with the top leagues in Germany, France, Italy and Spain.
Sean Dyche's Burnley side looked to have secured a crucial point in their fight to move clear of the bottom three but Eriksen broke their hearts with a clinical finish for third-placed Spurs in the 91st minute.
Arsenal can sustain a Europa League challenge but a top-four finish in the Premier League would be the best way to reach next season's Champions League, manager Arsene Wenger has said.
Liverpool a dramatic 2-1 victory over Leicester City at Anfield, thus maintaining the league leaders' 100 per cent start
Premier League champions Leicester City beat Everton 3-1 at the King Power Stadium on Saturday as a Jamie Vardy double completed a perfect coronation for Claudio Ranieri's miracle men.
The Premier League, which has been on hold since March 13, remains suspended until at least April 30 while lockdown measures are in place in the United Kingdom until May 7, when the government is set to review the current restrictions in place. The U.K government's cabinet minister responsible for sport said he has been in talks with the Premier League with the aim of getting football back on the field as quickly as possible.
Manchester United made it three wins out three as substitutes Marcus Rashford and Marouane Fellaini gave them a 2-0 victory over Leicester City at Old Trafford on Saturday to send them clear at the top of the Premier League.
Swedish striker Zlatan Ibrahimovic returned to Manchester United on a year-year contract "to finish what I started," the 35-year-old announced in a club statement on Thursday.
James Maddison scored a brilliant winner to help Leicester City come from behind and beat Tottenham Hotspur 2-1 in the Premier League on Saturday in a match dominated by VAR drama.
Ivorian Drogba, who had been playing in the United States for Phoenix Rising, had two spells at Chelsea, scoring 164 goals in 381 games having spearheaded the west London club's revival under owner Roman Abramovich.
Everton's Theo Walcott struck just after halftime to secure a 1-0 home win over Newcastle United, on Monday, that took the Merseysiders up to eighth in the Premier League, their highest position this season.
Images from the English Premier League matches played on Sunday
FA rules prohibit players and coaches from betting on any football activity or providing non-public information to any other person that is then used for betting.
Premier League leaders Manchester City turned on the style with a 3-1 win over Manchester United in their derby clash, on Sunday, leaving Pep Guardiola's unbeaten side two points clear of Liverpool.
Eriksen punctured Brighton's armour from Tottenham's 29th goal attempt -- 21 of which were from outside the penalty area.
The victory puts the pressure back on title rivals Liverpool who are at Cardiff City on Sunday and trail by a point with each side having played 34 games.
Manchester United substitute Marcus Rashford scored in stoppage time as they came from behind to beat Bournemouth 2-1 away and close the gap on the top four in an exciting Premier League clash.
Jose Mourinho has accused Manchester United's Premier League rivals of playing a "defensive game" ahead of the coming campaign but is making no secret of his side's own title aspirations.
City are two points behind leaders Liverpool, but have a game in hand
Manchester City forward Raheem Sterling struck twice as the Premier League champions beat Crystal Palace 3-1 at Selhurst Park on Sunday to go top of the table and heap pressure on title rivals Liverpool.
Rewind five years and Liverpool hosted Chelsea with three games remaining, knowing victory would have left them six points clear and a first league title since 1990 almost secure.
IMAGES from the English Premier League matches played on Saturday.
Wigan Athletic have fired manager Malky Mackay following their 2-0 home defeat by Derby County on Monday, the English Championship club said.
If City win their next league game at Everton on March 31 that will set up a Manchester derby at City's Etihad Stadium where a win over their arch-rivals would secure the title.
Liverpool face Spurs in the game of the weekend, a day after title rivals Manchester City travel to struggling Fulham.
Reading and Queens Park Rangers were relegated from the Premier League after the strugglers drew 0-0 on Sunday in a lacklustre and scrappy clash that epitomised their dismal seasons.
