Manchester City barely got out of second gear as they easily beat bottom club Huddersfield Town to close the gap on Premier League leaders Liverpool to four points on Sunday.
Chelsea's 3-0 win over Middlesbrough on Monday moved them seven points clear at the top with three games left and a win at West Brom will make them champions.
Bournemouth climbed to third place in the Premier League as they won away at Southampton for the first time with a 3-1 triumph in Friday's south-coast derby.
Liverpool opened up a seven-point gap at the top of the English Premier League with a 1-0 win at Brighton & Hove Albion on Saturday, while Arsenal's poor away form continued with a 1-0 defeat at West Ham United.
Buoyant Chelsea extended their Premier League lead and calmed nerves at Stamford Bridge with a 4-2 win over Southampton on Tuesday that moved them seven points clear of their nearest pursuers Tottenham Hotspur.
Riyad Mahrez scored one and set up another as Leicester City strolled to a 3-0 win over Huddersfield Town in the Premier League on Monday.
Reading and Queens Park Rangers were relegated from the Premier League after the strugglers drew 0-0 on Sunday in a lacklustre and scrappy clash that epitomised their dismal seasons.
Substitute Jesse Lingard struck twice in the second half as Manchester United fought back from 2-0 down to earn a 2-2 Premier League draw with Burnley at Old Trafford on Tuesday.
A Roberto Firmino hat-trick proved the highlight of Liverpool's 5-1 demolition of Arsenal as the Premier League leaders opened a nine-point gap over Tottenham Hotspur, who lost 3-1 to Wolverhampton Wanderers.
Tottenham Hotspur's status as Premier League title chasers was seriously harmed on Saturday as they fell to a first defeat in seven league games, losing the lead to go down 3-1 at home to Wolverhampton Wanderers.
Ole Gunnar Solskjaer continued his dream start as Manchester United caretaker manager with a 3-1 Premier League win over Huddersfield on his Old Trafford debut in the dugout on Wednesday.
Manchester City claimed the win required to finally end Liverpool's relentless attempt to dethrone them as Premier League champions as they hit back from a goal down to crush Brighton and Hove Albion on the south coast on Sunday.
Tottenham fell to seventh after winning just one league game in November but have since recovered with a morale-boosting Champions League victory over APOEL Nicosia, followed by two consecutive domestic wins to climb back into the top four.
Images from the English Premier League matches played on Saturday.
Images from the English Premier League matches played on Saturday
Mauricio Pochettino's Tottenham Hotspur can cement their status as the top dogs in the capital if they end an eight-year wait and defeat Arsenal in the North London derby on Sunday.
Currently, players from outside the EU must gain work permits and pass a series of qualification tests to get a "governing body endorsement" and work permit.
Chelsea moved 12 points clear of Arsenal, who suffered their fourth defeat in nine league matches, while fourth-placed Liverpool fell 13 point adrift after their wretched 2017 continued with a shock 2-0 defeat at resurgent Hull City.
Saturday's clash between Manchester United and Tottenham Hotspur at Old Trafford is already shaping up as an early-season eliminator to challenge runaway leaders Manchester City for the Premier League title.
Manchester City take on Chelsea and champions Manchester United meet West Ham United in the key fixtures of Saturday's programme in the English Premier League.
'Did the Moneyball philosophy get redefined in the domain of the cash-rich IPL, which has become an integral part of the cricketing ecosystem?' asks Atanu Biswas.
Top-class goals from Bernardo Silva and Sergio Aguero took Manchester City back to the top of the Premier League in a 2-0 win over Fulham at Craven Cottage on Saturday.
Champions Leicester City's alarming slump continued with a 3-0 Premier League defeat at Southampton on Sunday that left them just five points off the drop zone and firmly embroiled in a relegation fight.
'Before the start of the season I felt Manchester United will be a lot better this year and they were my tip for the title'
Liverpool take on Manchester United on Sunday, October 25, at 1930.
Huddersfield Town were left celebrating wildly after securing their Premier League safety on Wednesday with a dramatic and resilient 1-1 draw at Chelsea, a result that looks almost certain to condemn Swansea City to relegation.
After picking the ball out of his net several times in a 4-0 drubbing at Southampton two days earlier, Arsenal goalkeeper Petr Cech celebrated a record on Monday by keeping his 170th Premier League clean sheet.
Swansea City's hopes of salvaging their place in the Premier League suffered a potentially grievous blow as Ryan Fraser's deflected strike earned Bournemouth a 1-0 win on Saturday to secure another season of top-flight football for the Cherries.
Tottenham Hotspur have shown impressive durability in the Premier League lately, but they will need to be at their most steadfast to deny champions and league leaders Manchester City who travel to Wembley on Monday.
'It's very difficult to play football in these circumstances within 48 hours. It's amazing for the fans around the world, everybody has the Premier League, I'm more than happy to do that but it's very hard for the players'
Champions Manchester United take on cross-town rivals Manchester City in a highly anticipated encounter on Sunday.
Arsene Wenger's final match at Old Trafford as Arsenal manager ended in defeat with a stoppage time header from substitute Marouane Fellaini earning the points for second-placed Manchester United.
Brighton and Hove Albion's Tomer Hemed grabbed the only goal as they ended Newcastle United's three-match winning streak with a 1-0 victory on Sunday in a battle between two of this season's promoted sides.
Chelsea take on Hull City in the opening match of the English Premier League on Saturday, August 15, at 1715 IST.
Manchester United manager Jose Mourinho has dismissed suggestions that midfielder Paul Pogba faces a lengthy lay-off because of a hamstring injury sustained in the Champions League defeat of Basel on Tuesday.
Seasonal cheer has been scarce for Louis van Gaal after a six-match winless sequence for his Manchester United side intensified rumours that he will be sacked and Stoke City are unlikely to be offering any solace on Saturday.
Chelsea goalkeeper Kepa Arrizabalaga remains the club's first choice but manager Maurizio Sarri is still uncertain if the Spaniard will be recalled to the starting team for Sunday's Premier League trip to Fulham.
'The mental level, the day by day, everything must be consistent until the last day so one of the things we have to improve is consistency'
Manchester United battled back from two goals down to beat Newcastle United 3-2 at Old Trafford on Saturday as a 90th-minute winner from Alexis Sanchez completed a spirited comeback to ease the pressure on manager Jose Mourinho.
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