The 28-year-old Blake is one of six Americans to make the last eight at the Delray Beach International.
Top seed James Blake will play tournament specialist Xavier Malisse in the Delray Beach International final on Sunday.
Teenager Kei Nishikori became the first Japanese to reach an ATP final at the Delray Beach International.
Despite spraining her left ankle on Friday, the former world No. 1 is hopeful of playing the first round tie against Belgium.
'We feel blessed to have been able to play the game of doubles for so long. We are grateful to have had the opportunities in the beginning of the year to play and say our goodbyes to the fans.'
It was Paes's fourth title this year, having won in Halle, Gastaad and Canada.
Venus Williams will replace sister Serena, who suffered an ankle innjury, in the Fed Cup tie against Belgium.
Xavier Malisse took his second Delray Beach title by beating American James Blake 5-7, 6-4, 6-4.
Leander Paes, named a reserve in India's Davis Cup team for the Uzbekistan tie, is in line to win his first title of the season, albeit on the Challenger Tour, with Canadian partner Adil Shamasdin.
The duo beat James Blake and Jeff Morrison of the U.S. in the first round of the ATP International tennis championship in Florida.
The world No. 2 overcame shaky serving to beat Thomas Enqvist in the Davis Cup World Group quarer-final.\n\n
Croatian Marin Cilic continued his recent run of sizzling form by overpowering John Isner 7-6(7-5), 6-3 in a late-night showdown to advance to the Delray Beach Open final against South Africa's Kevin Anderson.
The second seeds beat top seeds Mark Knowles and Daniel Nestor in the final.
Eight-time Grand Slam winner Paes has now joined forces with Canadian doubles specialist Daniel Nestor while Klassen's coach Stefan de Kock revealed that the South African would now pair up with American Rajeev Ram.
Leander Paes, on Sunday, won his first title of the season, combining with Canadian Adil Shamasdin to lift the Leon Challenger Tour tennis tournament's men's doubles trophy after a straight-set triumph in Leon.
Canadian teenager Denis Shapovalov believes his first season on the ATP Tour has helped him grow into a better player and he is relishing the challenges ahead.
Indian tennis star Leander Paes and his German partner Andre Begemann knocked out top seeds Lukasz Kubot and Nenad Zimonjic in straight sets to storm into the semi-finals of the ATP Winston-Salem Open.
British No 1 Cameron Norrie overcame a slow start to beat Frenchman Hugo Gaston 6-3, 7-5.
Veteran Leander Paes brushed off the disappointment of Rio Olympics as he and his German partner Andre Begemann made it to the final of the ATP Winston-Salem Open beating Swede Robert Lindstedt and Pakistan's Aisam-ul Haq Qureshi in a close encounter.
The Australian fell to the floor in celebration after clinching the victory, before sticking a finger behind his ear and asking the raucous crowd to cheer louder.
Summary of sports events and persons who made news on Saturday
Bulgaria's Grigor Dimitrov edged second seed Andy Murray in a semi-final clash at the Acapulco International that finished in the early hours of Saturday morning to set up a title showdown against South Africa's Kevin Anderson.
IMAGES from Day 2 of the US Open played at Flushing Meadows in New York on Tuesday.
Marin Cilic became the first Croatian to win a Grand Slam singles final in 13 years with his victory at the US Open in New York on Monday.
Bulgaria's Grigor Dimitrov edged out South Africa's Kevin Anderson 7-6 (7-1), 3-6, 7-6 (7-5) in a three-hour slugfest to claim his second career title with victory in the Acapulco International final on Sunday.
American qualifier Steve Johnson is through to his first ATP Tour semi-final after an emphatic victory at the Delray Beach Open on Friday.
The Scottish broadcaster said Murray was self-isolating and still had hopes of competing in the Australian Open next month.
Battle-scarred Argentine Juan Martin del Potro clinched his 21st career title with a 6-4, 6-4 win over Kevin Anderson in the Mexican Open final in Acapulco on Sunday.
Croatia's Ivo Karlovic became the oldest ATP winner since Jimmy Connors in 1989.
Jack Sock celebrated a pair of firsts on Friday by powering past fourth seed Kei Nishikori 6-3, 2-6, 6-2 to book a date with Roger Federer in the semi-finals of the BNP Paribas Open in Indian Wells, California.
Top seed Simona Halep came back from a set down for the third time in the tournament to beat Kazakhstan's rising star Elena Rybakina 3-6, 6-3, 7-6(5) to win the Dubai Duty Free Tennis Championships for the second time on Saturday. In a battle that lasted nearly two-and-a-half hours, the match came down to a tiebreak where two shots that went agonisingly wide for Rybakina eventually decided the title in front of a noisy crowd that constantly chanted Halep's name.
Davis Cup champions Britain were locked at 1-1 with Japan after the opening two singles of their World Group, first-round tie on Friday after Andy Murray gave the hosts the lead.
A summary of sports events and persons who made news on Thursday
Under the lights on the stadium court, Williams smashed 39 winners to defeat Azarenka 7-5, 6-3 in a rematch of the 2016 final, which the Belarusian won.
Summary of sports events and persons who made news on Monday
A resurgent Marin Cilic blasted his way by sixth seed Tomas Berdych 6-2, 6-4, 7-6 (4) on Thursday to become the first Croatian to reach the U.S. Open semi-finals since his coach Goran Ivanisevic in 1996.
Laslo Djere won his first ATP title at the Rio Open on Sunday and then captured the hearts of the Brazilian crowd with a victory speech dedicated to his parents, both of whom died from cancer.
Top seed Stanislas Wawrinka lifted his fifth ATP World Tour title and second Chennai Open trophy after a convincing straight sets win over Edouard Roger-Vasselin in the final on Sunday.