AC Milan have made a habit of muddling through under coach Massimiliano Allegri and they did it again on Wednesday by scraping into the Champions League knockout stage with a performance which left opponents Ajax Amsterdam fuming.
Three time European champions Inter Milan were stunned 2-0 at home by Israeli side Hapoel Beer-Sheva and Manchester United were floored by a late goal from Feyenoord as the Europa League group stage got underway on Thursday.
Images from the EPL matches played on Saturday
Having absorbed the body blow of losing striker Radamel Falcao in the close season, Atletico Madrid have emerged as genuine contenders to break the title stranglehold of Real Madrid and Barcelona.
The value of an in-form striker was underlined as Tottenham Hotspur, Liverpool and Athletic Bilbao needed goals from pivotal front men to grab vital wins that booked places in the Europa League last 32 on Thursday.
Images from the UEFA Champions League quarter-final first leg matches played on Wednesday
Stephan El Shaarawy took a small step towards refuelling his career at Monaco when the AC Milan loanee came off the bench to rescue a late 1-1 draw against Tottenham Hotspur in the Europa League's second round of group matches on Thursday.
News of all that's transpired on and off the football field
News of all that's transpired on and off the football field
Summary of sports events and persons who made news on Monday
Zlatan Ibrahimovic bagging four goals, while Juventus and Bayern Munich preserved their leads and FA Cup holders Arsenal were dumped out of the competition.
Ten-man Premier League leaders Leicester City lost at title-chasing Arsenal, while La Liga pacesetters Barcelona crushed Celta Vigo and Juventus took over from Napoli at the top of Serie A by edging their rivals.
Manchester United are satisfied with their transfer business and under no pressure to sign a fourth player in the current window, manager Jose Mourinho said.
Barcelona's rampant trio of Neymar, Luis Suarez and Lionel Messi all found the net at the weekend and unsung Leicester City found themselves in the record books when their England striker Jamie Vardy scored for the 11th straight game.
News of Van Gaal's impending departure from the club leaked out minutes after Saturday's 2-1 extra-time victory over Palace and, following relentless media speculation and a day of negotiations, it was confirmed by both sides on Monday evening.
Barcelona followed up last weekend's 3-1 defeat at Real Madrid with another reverse on Saturday, squandering a host of chances to lose 1-0 at home to Celta Vigo and handing the lead in La Liga to their arch rivals.
Real Madrid captain Sergio Ramos risks being hit with an extra game suspension which would rule him out of a potential Champions League quarter-final first leg after admitting he got booked on purpose in Wednesday's 2-1 win at Ajax Amsterdam.
A summary of sports events and sports persons, who made news on Thursday
While Lyon rallied to hold Leipzig 2-2 after a Memphis Depay strike, it was the English clubs who made a mark on the night. Liverpool and Chelsea moved into the last 16 with contrasting wins and now all four English clubs, including Manchester City and Tottenham Hotspur, are in the Champions League knockouts this season.
News of all that's transpired on and off the football field
Chelsea moved within touching distance of a first Premier League title in five years with a 1-0 win over Manchester United while Lionel Messi reached a landmark with his 400th career goal for La Liga leaders Barcelona.
News of all that's transpired on and off the football field
News of all that's transpired on and off the football field
Real Madrid were the big winners in Spain as their success at Almeria was followed by a Barcelona draw and a surprise Atletico Madrid defeat.
Lionel Messi fittingly sealed Barcelona's 26th La Liga title on Saturday by coming off the bench to score the goal in a 1-0 win over Levante in front of a jubilant Nou Camp crowd, who celebrated a remarkable eighth league crown in 11 years.
Barcelona and Atletico Madrid led a Spanish Armada into the Champions League last 16 with home wins on Wednesday and in-form Aaron Ramsey steadied Arsenal's boat with a battling win against rocky Borussia Dortmund.
News of all that's transpired on and off the football field
Hegerberg hat-trick fires Lyon to fourth straight Champions League
Cristiano Ronaldo bagged his first five-goal haul in Real Madrid's 9-1 hammering of Granada while title-chasing Bayern Munich and Chelsea won again in Germany and England.
News of all that's transpired on and off the football field
News of all that's transpired on and off the football field
News of all that's transpired on and off the football field
In England, the celebrations went on at Leicester City as they marked their fairytale Premier League success with another win while champions Juventus' long unbeaten streak in Italy came to an end.
La Liga leaders Real Madrid were thumped 4-0 away by city rivals Atletico Madrid to open up the Spanish title race, while Chelsea strengthened their hold on top spot in the English Premier League after a 2-1 win at Aston Villa.
News of all that's transpired on and off the football field.
Manchester City claimed the win required to finally end Liverpool's relentless attempt to dethrone them as Premier League champions as they hit back from a goal down to crush Brighton and Hove Albion on the south coast on Sunday.
This and more from the happenings in the world of football
Here is the round-up of all the football action across Europe on the weekend
News of all that's transpired on and off the football field
Manchester City made sure of third place in the Premier League when they romped to a 5-0 win at Watford on Sunday to ensure a Champions League berth for next season.