Barcelona forwards Lionel Messi, Philippe Coutinho and Luis Suarez combined to devastating effect to hammer Girona 6-1 on Saturday as they went 10 points clear at the top of La Liga and set a club record of 32 games unbeaten in the league.
Madrid were not at their best but moved three points clear of rivals Barcelona.
Chris Froome has been so strong on this year's Tour de France that at times he appears to have been toying with his rivals.
Dutchman Ronald Koeman has signed a two-year-deal with Barcelona.
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Valencia ended a miserable week on a high when they came from behind to snatch a 3-2 win at struggling 10-man Deportivo La Coruna that lifted them to fifth in La Liga on Saturday.
Here are five talking points from the weekend's action:
Ansu Fati is the second-youngest player to represent the Catalan giants in La Liga aged 16 years and 298 days.
Images from the football matches played across Europe on Sunday.
Messi, who has struggled for form in recent weeks due to a niggling injury, looked on a mission to grab the winner and after twice coming close he completed his treble to put Barca ahead in the 85th minute, reacting quickly to a poor Sevilla clearance to dink the ball over goalkeeper Tomas Vaclik.
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A month after completing a two-year ban for doping, Alberto Contador showed that he was still a force to be reckoned with as he won his second Vuelta a Espana title on Sunday.
Real Madrid and Atletico each slipped 10 points behind La Liga leaders Barcelona after an intense Madrid derby finished goalless and the Catalans picked up an 11th victory in 12 games by winning 3-0 at Leganes.
Lionel Messi celebrated his sixth Ballon D'Or award with a brilliant hat-trick as Barcelona moved back top of La Liga with an emphatic 5-2 victory over Real Mallorca.
Barcelona snatched a late 2-1 win at Getafe with Paulinho's strike sending them seven points clear of arch-rivals Real Madrid at the top of La Liga.
Lionel Messi scored twice as King's Cup holders Barcelona moved comfortably into the quarter-finals by thrashing Celta Vigo 5-0 at the Nou Camp in their last 16 second leg game on Thursday.
AS Roma pulled off one of the great Champions League comebacks by knocking Barcelona out with a remarkable 3-0 win in their quarter-final second leg on Tuesday, overcoming a 4-1 deficit from the first game to reach the last four on away goals.
News of all that's transpired on and off the football field
Chris Froome tightened his grip on the Tour de France on Wednesday, extending his overall lead to well over three minutes at the halfway mark with a predictably brilliant performance in the time trial.
"It's better for Messi to play as he is the best in the world and he gives you a boost but we should be very proud as a team, as we showed that we are a great team without Messi and we have a great coach (Ernesto Valverde)," Suarez said.
News of all that's transpired on and off the football field
Images from Saturday's La Liga action.
Setien's complaint piled yet more pressure on president Josep Maria Bartomeu less than an hour after a group seeking his removal announced they had gathered enough signatures to force a vote of no-confidence against him.
Lionel Messi scored twice to earn Barcelona a 2-0 derby win over Espanyol and send them 13 points clear at the top of La Liga on Saturday.
It was a dramatic night at the Champions League as Barcelona's Anssumane Fati -- 17 years and 40 days old - became the youngest to net a goal in the competition. Last season's semi-finalists, Ajax were eliminated by Valencia while Napoli's coach Ancelotti was shown the door despite the team's progress. Here are Images from the Champions League matches played on Tuesday
'We have to do a lot of self criticism because this is the second time that the same thing has happened to us. We cannot commit the same mistake two years in a row, there are many things we need to consider and think about'
Lionel Messi had to wait 12 years and endure a goal drought of eight games against Chelsea but he finally broke his duck in Tuesday's 1-1 Champions League last 16, first leg draw.
Real Madrid dropped points for the third time in seven games since Zinedine Zidane's return as they were held to a 0-0 draw away to Getafe in La Liga on Thursday, which harmed their neighbours' hopes of a top-four finish.
Holders Barcelona reached the King's Cup semi-finals with a 2-0 win over Espanyol on Thursday to overcome a first-leg deficit on a night when new signing Philippe Coutinho made his debut.
With the Catalans shorn of three of their top forwards, all eyes will be on Griezmann in his first appearance at the Camp Nou since his 120-million-euro ($133 million) move from Atletico Madrid, and not least because Barca need a win to kickstart their season.
Betis fans bow to 'extraordinary' Messi after sublime hat-trick Lionel Messi is used to receiving adulation at the Nou Camp but on Sunday he got a rapturous reception from rival supporters for a majestic hat-trick in Barcelona's 4-1 win at Real Betis. Messi opened the scoring with an unstoppable free kick then combined with devastating effect with Luis Suarez to carve Betis open and score a second goal right before halftime. The Argentine saved his best goal for last, completing a victory which took Barca 10 points clear at the top of La Liga with a spectacular first-timed chip from the edge of the area after playing a one-two with Ivan Rakitic. Beaten Betis goalkeeper Pau Lopez looked on in awe while the home supporters, renowned for devotion to their side, rose to their feet, bowed down to Messi and chanted his name. "Even though the opposition concedes goals to Messi they can still enjoy this unbelievable era which he has created, they enjoy it too and today they recognised that," said Barca coach Ernesto Valverde. "It's significant that they gave him this ovation, it's an acknowledgement. Our rivals' supporters have to suffer him but they also appreciate him, because of the player he is. "Leo's performance was extraordinary, he got three goals but he could have got four, that shows you how good he is." Betis coach Quique Setien commended his supporters for their treatment of Messi while saying he felt honoured to work in the same era as the Argentine. "I really like the fact that our supporters showed their appreciation for a great player, today he really made us suffer," Setien said. "It's only fair and it's right to recognise this, our fans behaved in an extraordinary way and I'm very proud of them. I've seen some magnificent players do great things but no-one can match the things Messi has done over the last 12 years. "It's a privilege to have been able to start this era with him and see him in action every weekend." The five-times world player of the year moved on to 39 goals in all competitions this season with two months still left in the campaign. It was Messi's 51st career hat-trick but he could not recall receiving such applause from a rival team's fans. "I cannot remember anything like this before and I'm very grateful for the fans' reaction," Messi said. "I'm very grateful to them and happy for the victory, which was very important."
Villarreal romped to a 5-0 home victory over promoted Tenerife on Sunday, continuing their revival after a poor start to the La Liga campaign.
Real Madrid moved into the semi-finals of the Champions League after their makeshift defence held on for 0-0 second-leg draw with Liverpool at Anfield on Wednesday to complete a 3-1 aggregate win.
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Santiago Solari got off to the perfect start as Real Madrid's interim coach when his side thrashed Melilla 4-0 in the Copa del Rey on Wednesday.
Messi ran amok at Wembley Stadium, slicing Spurs apart with incisive passes from deep, such as the one that allowed Philippe Coutinho to open the scoring, and was as dangerous as ever in front of goal, firing in the Catalan side's final two goals to end their winless run of three games.
Manchester Utd's Fred receives racist abuse after defeat by Liverpool.
The Catalans will not just be looking to extend their domestic hegemony, though, as they have spent a combined 250 million euros ($280 million) on a renewed bid to win the Champions League.
It was Messi's 30th goal in 39 competitive games against Atletico
