Greece's Tsitsipas battled back from 3-5 down in the third set to eliminate Medvedev with a 6-3, 6-7(11), 7-6(1) win to set up a showdown on Friday with Rublev for the Red Group's other semi-final spot.
Zverev was left wondering why he has been struggling to get into his matches
World number one Novak Djokovic earned his 1,000th tour-level victory by beating Casper Ruud 6-4, 6-3 on Saturday to reach the Italian Open final.
AC Milan entered the Champions League quarterfinals for the first time in eleven years, with a draw in the round of 16 second leg against Tottenham Hotspurs.
Holders Real Madrid breezed past Chelsea into the semi-finals of the Champions League with Rodrygo's double securing a 2-0 win at Stamford Bridge.
Wimbledon debutant Eubanks ends Tsitsipas's challenge in fourth round.
World number one Carlos Alcaraz sailed into the Paris Masters third round with a 6-4, 6-4 win over Yoshihito Nishioka but Rafael Nadal and Daniil Medvedev both slumped to surprise losses on Wednesday.
World number one Novak Djokovic, bidding for a record-equalling sixth title at the event, is in the Tokyo group with Russian Daniil Medvedev, Germany's Alexander Zverev and Argentine first-time Diego Schwartzman.
Inspired Garcia goes from Cincinnati qualifier to champion
Petra Kvitova overcame a sluggish start and 10 double faults to beat Madison Keys 6-7(6), 6-4, 6-3 on Saturday and advance to the final of the Cincinnati Open, where she will face Caroline Garcia, the first qualifier to reach the final of a WTA 1000 tournament.
Andy Murray may have been the forgotten man at the US Open but gave the crowd and Stefanos Tsitsipas a match to remember, forcing the third seed to grind out a 2-6, 7-6(7), 3-6, 6-3, 6-4 win on Monday and avoid the opening round shocker.
The ATP Finals, in its 50th edition, is being staged in London's O2 Arena for the 12th and last time before it moves to Turin and sadly plans for a vibrant farewell party in front of the usual sell-out crowds has been scuppered by the COVID-19 pandemic.
Djokovic did not drop a set en route to the final in Rome
Nadal, bidding for a record-extending 14th French Open title, won the first five games of the match as he looked on course to repeat his drubbing of the Serb in last year's final.
Rafa Nadal returned from an injury layoff to beat Miomir Kecmanovic 6-1 7-6(4) on Wednesday
'The bubble makes it really tiring week by week'
Barcelona clinched a 1-0 away win at Atletico Madrid, while AS Roma held AC Milan to a 2-2 draw.
Holger Rune crashed out to Yoshihito Nishioka in the ATP 250 Adelaide International 1 first round.
He was drawn in the toughest half of the draw with Nadal as well as in-form Spanish teenager Carlos Alcaraz and world number three Alexander Zverev, who could clash in the last eight.
Kyrgios added that he had been in communication with Tennis Australia chief executive Craig Tiley and United Cup tournament director Stephen Farrow about his injury.
Formula One and the championship-leading Red Bull team mourned the death of the energy drink company's Austrian founder Dietrich Mateschitz on Saturday at the age of 78.
Djokovic struggled to find his range early in the contest as Spaniard Davidovich Fokina raced to lead
Madison Keys swept past Wimbledon champion Elena Rybakina 6-2, 6-4 at the Cincinnati Open on Friday, setting up a semi-final clash with Petra Kvitova after the Czech defeated Ajla Tomljanovic.
Serbia's Novak Djokovic outclasses Russia's Andrey Rublev to set up a meeting with unseeded Tommy Paul in the semi-finals of the Australian Open on Wednesday.
Images from Day 10 of the 2022 Australian Open in Melbourne on Wednesday.
Kingsley Coman came back to haunt Paris St Germain again as he earned Bayern Munich a 1-0 win in their Champions League last-16 first leg in Paris on Tuesday.
'My arm has been -- I have had an issue there for quite a while now. It has gotten bigger in the last couple of weeks, so I'm just trying to protect it.'
Russian Andrey Rublev has become the fifth singles player to qualify for the season-ending ATP Finals in Turin next month, the men's tour said.
Novak Djokovic secured a semi-final place at the ATP Finals with a 6-3, 6-2 victory over Russian Andrey Rublev on Wednesday, his 50th match win of the year, while Stefanos Tsitsipas withdrew from the tournament due to an elbow injury.
Daniil Medvedev was fined for an outburst against the umpire
Sparks flew when they met for the first time on the ATP Tour in Miami, with Medvedev confronting the Greek over his on-court conduct.
Rafael Nadal's hopes of winning the year-ending ATP Finals for the first time live on after the Spaniard beat defending champion Stefanos Tsitsipas 6-4, 4-6, 6-2 on Thursday.
IMAGES from Day 9 of the French Open at Roland Garros in Paris on Monday.
Manager Carlo Ancelotti said striker Kylian Mbappe's decision to snub Real Madrid and stay at Paris St Germain was not a distraction ahead of Saturday's Champions League final
Casper Ruud has become the first Norwegian to book a place in the season-ending ATP Finals, leaving one spot to be filled at the tournament in Turin, Italy later this month.
Djokovic has won the last three editions of Wimbledon in 2018, 2019 and last year
The Australian brought his extraordinary brand of improvised tennis theatre to the world's greatest tennis stage
Novak Djokovic produced a stunning performance to thrash Frances Tiafoe in his first match since winning Wimbledon in July to edge Team Europe ahead in the Laver Cup on Saturday.
Eight-time Wimbledon champion Roger Federer, who turns 40 this year, takes on Frenchman Adrian Mannarino in round one.
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