Liverpool romed into the Europa League final with a 3-0 win over Villarreal on another magical night at Anfield to tee up a showpiece clash with holders Sevilla who swatted away visitors Shakhtar Donetsk 3-1 on Thursday.
Spain became the first country to have five teams in the Champions League group stage in one season after Valencia squeezed past Monaco .
Portugal, Denmark, Poland, Serbia, Austria, Croatia and Ukraine are among countries which will again be able to enjoy league football, albeit in unusual circumstances with no spectators allowed at games.
A round-up of Wednesday's league stage matches in the UEFA Champions League.
A round-up of Tuesday night's matches in the UEFA Champions League.
Manchester United veteran Ryan Giggs set a Champions League record on Wednesday but his side had little else to celebrate after a 1-1 draw at Shakhtar Donetsk in Group A.
David Moyes can take solace in avoiding another home defeat and a 51-year low but his Manchester United side will have to raise their game considerably if they are to go much further in the Champions League.
Images from the UEFA Champions League matches played on Tuesday night.
Images from the Champions League matches played on Wednesday
David Moyes said Manchester United's players are hurting after consecutive Premier League defeats at Old Trafford but he is 'responsible' for the club's poor start to the season.
The dismissal of Nani for a second-half foul on Alvaro Arbeloa wins hands down as the talking point of the game.
(Reuters) - Real Madrid, Manchester United and Paris St Germain reached the last 16 of the Champions League on Wednesday on a night when the goals flowed all over Europe with United the highest scorers in a 5-0 win at Bayer Leverkusen.
Images from Tuesday night's UEFA Champions League group stage matches.
Borussia Dortmund defender Mats Hummels could have been facing a dressing down from coach Juergen Klopp but ended up the hero with the equaliser in Wednesday's 2-2 Champions League last-16 first-leg match.
Captain John Terry will be back to plug Chelsea's porous rearguard on Wednesday when the holders bid to avenge last month's defeat by Shakhtar Donetsk and wrest back control of Champions League Group E.
Rattled by embarrassing domestic defeats, Chelsea looked jittery before Olivier Giroud settled their nerves with a close range tap-in shortly after halftime at StamfordBridge following good work by N'Golo Kante and Willian in the build-up.
IMAGES from the Champions League matches played on Tuesday
Edinson Cavani scored early for Paris St Germain but a series of wasted chances came back to haunt them as Ajax Amsterdam equalised late to deny the French a winning start on the road in a 1-1 draw in Champions League Group F on Wednesday.
Liverpool laboured to a 2-0 win over Denmark's Midtjylland on Tuesday as a goal from Diogo Jota and a Mohamed Salah penalty secured a hard-fought Champions League Group D victory at Anfield.
Chelsea will start the defence of the Champions League trophy they won so dramatically last season with a Group E match against former winners Juventus at Stamford Bridge.
Six clubs enter this week's final round of Champions League group matches harbouring hopes of grabbing one of the three last-16 places still up for grabs although for holders Chelsea their fate is beyond their control.
Lionel Messi fired Barcelona into the last 16 of the Champions League with two goals in their 3-0 victory at Spartak Moscow on Tuesday but holders Chelsea are walking a tightrope after a crushing defeat by Juventus.
IMAGES from the Europa League semifinal played between Manchester United and Sevilla in Cologne on Sunday.
Shakhtar Donetsk led the way for the Champions League underdogs as they beat holders Chelsea 2-1 while former European champions Barcelona and Manchester United came from behind to maintain perfect starts on Tuesday.
Barcelona's fourth defeat of the season left them seventh in the standings on 14 points after 10 games, 12 points behind leaders Atletico.
Inter Milan midfielder Christian Eriksen scored his first goal for the club since last month's move from Tottenham Hotspur to set up a 2-0 win at Ludogorets Razgrad in their Europa League last 32, first leg on Thursday. Getafe pulled off a surprise 2-0 home win over last year's Champions League semi-finalists Ajax Amsterdam, while Manchester United were held 1-1 at Club Brugge in wet and windy conditions. Wolverhampton Wanderers' Diogo Jota scored a second successive hat-trick in the competition to lead his side to a 4-0 victory over Espanyol and Arsenal won 1-0 at Olympiakos Piraeus with a late Alexandre Lacazette goal.
Factbox on the 20 Premier League clubs after the transfer window closed.
Images from football action around European leagues played on Sunday
Barcelona have decided to appeal UEFA's proposal to ban Andres Iniesta for one Champions League match for deliberately collecting a yellow card.
Lionel Messi scored his maiden goal for Paris St Germain in Tuesday's 2-0 Champions League victory against Manchester City.
After Tuesday's 11-goal fireworks the matches are likely to be tighter in Wednesday's Champions League quarter-final first legs as Chelsea entertain Manchester United and Barcelona host Shakhtar Donetsk.
Chelsea have the chance to avenge their shattering penalty shootout defeat to Manchester United in the 2008 final after being drawn to play them in the quarter-finals of the Champions League on Friday.
Cristiano Ronaldo delivered the knockout blow for Real Madrid in their aristocratic battle with AC Milan on Tuesday, as Arsenal, Chelsea and Bayern Munich maintained their own perfect Champions League starts.
Inter Milan goalkeeper Julio Cesar was called up by Brazil for the first time since the 2010 World Cup on Tuesday for next month's friendly away to France. The 23-man squad picked by coach Mano Menezes includes uncapped midfielders Jadson of Shakhtar Donetsk and Renato Augusto of Bayer Leverkusen.
Barcelona could be at full strength in Tuesday's Champions League clash at Shakhtar Donetsk despite the luxury of a 5-1 advantage from the quarter-final first leg, coach Pep Guardiola suggested on Monday.
Arsenal hope to complete a full set of English clubs going into the Champions League knockout phase on Wednesday though there could be a few anxious faces at The Emirates when they take on Partizan Belgrade.
Barcelona suffered a 2-1 defeat at Arsenal and AS Roma's miserable run continued with a 3-2 home loss to Shakhtar Donetsk in Champions League last-16 first-round matches on Wednesday.
"First we have to play football and see what happens. Maybe we can then score a goal and create an atmosphere in the stadium."
Claudio Ranieri resigned as coach of AS Roma following their shock 4-3 loss at Genoa on Sunday in a game they had led 3-0.