Mathieu Valbuena and Karim Benzema, embroiled in a sextape scandal, were omitted from France's squad on Thursday for the games with Germany and England later this month while Hatem Ben Arfa was recalled.
The Catalans are overwhelming favourites to win the game and have an outstanding home record in the Champions League, remaining unbeaten at the Nou Camp in the competition since losing to Bayern Munich in 2013.
A summary of Thursday's matches in the Europa League.
Barca's Suarez in firing line after European away goals drought
News of all that's transpired on and off the football field.
Real Madrid dug deep in a 3-0 home win against lowly Alaves in the La Liga, but Ligue 1 leaders Paris St Germain their second Ligue 1 loss of the season.
News of all that's transpired on and off the football field
Images from action in the Europa League matches on Thursday.
European football was given good and bad reminders of its past on Thursday with an impressive 2-0 win for once-mighty Ajax Amsterdam over Schalke 04 in one Europa League game but ugly scenes in the crowd at Lyon delaying another.
Ronaldo's replacement Dybala scored in the 77th minute with a goal the Portuguese would have been proud of. After a quick exchange of passes, the Argentine twisted past Alessio Romagnoli and beat Gianluigi Donnarumma with a right foot shot.
One goal determined the outcome of the Champions League final on Sunday but there could be no doubt that Bayern Munich deserve to be crowned European champions for the sixth time. With a 1-0 victory over Paris St Germain courtesy of Kingsley Coman's header, Bayern have achieved what no team have managed in Europe's elite club competition -- win every game.
Paris St Germain fielded a second-string side and were held 0-0 at home by Montpellier in Ligue 1 on Saturday as they restored a 23-point advantage at the top of the table.
Coutinho, who arrived from Liverpool for a club record 165 million euros ($185.18 million) in January 2018, has so far shown little to suggest he will be able to compensate for Frenchman Ousmane Dembele's absence against Lyon in the UEFA Champions League tie.
The Catalans have kept five clean sheets in their last six games, which bodes well for their title run in.
While Pep Guardiola has brought two Premier League titles, smashed records and produced some of the most glorious football the club's fans have ever seen -- European success remains elusive to his team.
A summary of Thursday's second leg quarter-final matches in the Europa League.
France international striker Karim Benzema, who is embroiled in a blackmailing scandal, is not afraid of possibly missing the Euro 2016 finals on home soil, the Real Madrid player said on Sunday.
News of all that's transpired on and off the football field
PSG make winning start as Messi arrival looms
News of all that's transpired on and off the football field
Neymar was in a class of his own again on Sunday, scoring a double to help Paris St Germain extend their Ligue 1 lead to 10 points with a 2-0 win at Lille. The Brazilian dedicated his goal to former Los Angeles Lakers player Kobe Bryant, who died in a helicopter crash on Sunday, by raising two fingers in one hand and four fingers with the other to signal the number 24 -- Bryant's shirt number.
Ten-man Paris St Germain got the defence of their Ligue 1 title off to a good start when Lucas's second-half strike earned them a 1-0 win at Lille on Friday.
A round-up of Wednesday's action in the UEFA Champions League.
While Lyon rallied to hold Leipzig 2-2 after a Memphis Depay strike, it was the English clubs who made a mark on the night. Liverpool and Chelsea moved into the last 16 with contrasting wins and now all four English clubs, including Manchester City and Tottenham Hotspur, are in the Champions League knockouts this season.
Cristiano Ronaldo scored a perfect hat-trick inside 32 minutes as Juventus bounced back from their midweek Champions League exit by beating Cagliari 3-1 away in Serie A on Sunday.
Leicester pushed forward after the interval but were caught out on the break in the 64th minute when Ritchie's pass released Wilson who coolly rounded Schmeichel before sliding home.
IMAGES from soccer matches played across Europe on Sunday.
Lionel Messi scored one penalty and missed another as Barcelona beat Real Valladolid 1-0 on Saturday to open up a seven-point lead at the top of La Liga.
Arteta, who will lead City in their Champions League opener against Olympique Lyonnais on Wednesday because manager Pep Guardiola is suspended, also said that his team were better placed to challenge for top European honours this season.
Players from both teams took a knee in solidarity with the Black Lives Matter movement before Wednesday's game at Toyota Stadium in Frisco, Texas, but their gesture was overshadowed by booing from a small section of fans.
Olympique de Marseille will lead Ligue 1 into the two-week break thanks to Michy Batshuayi's half-volleyed winner in a 2-1 home victory over Lille on Sunday.
Real Madrid's Croatia midfielder Luka Modric was named winner of the 2018 Ballon d'Or on Monday, breaking Cristiano Ronaldo's and Lionel Messi's decade-long hold on the prestigious award.
Paris St Germain continued their irrepressible march towards a fourth consecutive Ligue 1 title with a 5-1 home win against Olympique Lyonnais to move 17 points clear at the top.
France and Real Madrid striker Karim Benzema insisted on Wednesday he has done nothing wrong after being put under investigation in France in connection with an alleged attempt to blackmail a fellow international with the use of a sex video.
Lionel Messi was lauded by opposition supporters on Sunday after he scored an outstanding hat-trick in Barcelona's 4-1 win at Real Betis, which put the Catalans 10 points clear at the top of La Liga with 10 games remaining.
Pep Guardiola will return to the Nou Camp in the Champions League group stage after his new club Manchester City were drawn against his former Barcelona team on Thursday. The two sides were drawn in Group C alongside Borussia Moenchengladbach and former European champions Celtic in one of the toughest of the eight sections. Spanish coach Guardiola, who won the Champions League twice with Barca, faced the Catalans when he was in charge of Bayern Munich two seasons ago and suffered a 5-3 defeat in the semi-finals.
Images from football matches played in Europe on Sunday.
Manchester City have never gone past the semi-final stage of Europe's premier club competition.
Ajax Amsterdam produced a performance worthy of the club's illustrious past when they crushed Olympique Lyonnais 4-1 on Wednesday to move to the brink of their first European final since 1996.
Images from the FIFA World Cup qualifier matches played on Tuesday night.