Hull City and Swansea City earned valuable victories in their battle for Premier League survival but Middlesbrough slid further towards the drop after a 4-0 hammering at Bournemouth.
Chelsea beat Newcastle United 2-0 for a 10th successive Premier League home win at their Stamford Bridge stronghold on Saturday to reassert themselves as Premier League leaders while champions Manchester City drew at Everton.
Basle FC lead online mocking of Liverpool.
Borussia Dortmund have signed Manchester United winger Adnan Januzaj on loan for a season, the German club said on Monday.
Italy striker Mario Balotelli has joined Liverpool from AC Milan on a "long-term" deal, the Premier League club said on Monday.
You would have been hard pressed at the start of the season to find anyone to bet on Liverpool's Brendan Rodgers becoming the first Premier League manager to get the sack, but he is now the bookies' joint favourite.
Liverpool's Raheem Sterling netted a sharply-taken double in a 3-1 win over Bournemouth on Wednesday to set up a League Cup semi-final with Chelsea.
Liverpool's UEFA Champions League challenge ended in a 1-1 draw against FC Basel, who booked their spot in the last 16.
Here are five talking points from the weekend's action:
Liverpool's half-baked pre-season transfer dealings have come back to bite them with Brendan Rodgers admitting his side have lacked the quality to finish in the Premier League's top four.
Liverpool's half-baked pre-season transfer dealings have come back to bite them with Brendan Rodgers admitting his side have lacked the quality to finish in the Premier League's top four.
Photos from the English Premier League matches played on Wednesday
The Reds' manager believes his team has the ability to finish in the top four and qualify for Champions League next season.
'We're starting to see signs of getting back to where we were'
News of all that's transpired on and off the football field
Aston Villa will meet holders Arsenal in the FA Cup final next month.
Benfica's Oscar Cardozo scored a hat-trick in a 4-3 extra-time win over Lisbon rivals Sporting in the Portuguese Cup last 32 on Saturday with Luisao grabbing the winner after a blunder by visiting keeper Rui Patricio.
Seventh-placed Liverpool, who have 14 points from nine matches, travel to a Newcastle side buoyed by their League Cup victory over Manchester City.
Chelsea ticked off three more points in their Premier League title quest with a 2-1 victory over Manchester City on Wednesday but Tottenham Hotspur's Houdini-like 3-1 win at Swansea means the race is far from over.
Liverpool manager Brendan Rodgers took an upbeat view on a dismal night as the five-times European champions were bundled out of the Champions League following a 1-1 draw with FC Basel at Anfield on Tuesday.
Four-time European Champions Ajax Amsterdam were felled at the first hurdle of the continent's second tier Europa League on Thursday, exiting in the group stage two days after rivals PSV Eindhoven celebrated long-awaited success.
Manchester City failed in an audacious transfer deadline day move for Leicester City midfielder Riyadh Mahrez, British media reported on Wednesday.
Liverpool's 1-0 defeat by Aston Villa on Saturday was more than an early season setback - it raised the question of whether they have the strength in depth to cope with the dual challenge ahead of them this term.
Arsenal delivered a brutal lesson in fast-paced Premier League football to beat Liverpool 4-1 on Saturday, maintaining their faint title aspirations and almost certainly dashing their opponents' hopes of a top-four finish.
Arsenal climbed into the top four with a laboured 2-1 win over Leicester City.
Dejan Lovern talks about his ambition to become a Liverpool legend at Anfield and why victory in the Merseyside derby against Everton could propel Reds' chances this season.
News of all that's transpired on and off the football field
Karim Benzema came off the bench to score 13 minutes from time and ruin any chance of a dream result for resilient Ludogorets as holders Real Madrid carved out a patchy 2-1 win in Wednesday's Champions League Group B match.