Adrian fired past opposite number and Spanish compatriot Joel Robles immediately after the Everton keeper had crashed his spot kick against the crossbar as West Ham won 9-8 on penalties.
Tottenham Hotspur have shown impressive durability in the Premier League lately, but they will need to be at their most steadfast to deny champions and league leaders Manchester City who travel to Wembley on Monday.
Manchester City completed a resounding demolition of West Ham United by winning the second leg of their League Cup semi-final 3-0 on Tuesday to book their place in the final at Wembley 9-0 on aggregate.
Images from the English Premier League matches played on Sunday
IMAGES from the EPL matches played on Wednesday
Petr Cech helped the Gunners enjoy a rare victory over Jose Mourinho's side on Sunday.
Arsenal's best chance to equalise came from a Granit Xhaka free kick which looked destined for the top corner until the Gunner's former keeper Emiliano Martinez at full stretch pushed it around the post with a fingertip save.
Guardiola beat out Chelsea's Antonio Conte, Burnley's Sean Dyche, Liverpool's Juergen Klopp, Manchester United's Jose Mourinho and Arsenal's Arsene Wenger for the award.
Klopp fined by FA for referee comments after West Ham draw
Third-placed Chelsea will be eager to bounce back from their 1-0 defeat by relegation-threatened West Ham United on Saturday but face a tough test against a Huddersfield side that have won four and drawn two of their eight home league games this season.
Manchester City beat West Ham United 2-0 at the Etihad Stadium on Sunday to win the English Premier League title for the second time in three seasons.
Stoke thought they had secured all three points and their first away win since October when substitute Peter Crouch knocked a loose ball into the back of the net after West Ham's England goalkeeper Joe Hart spilled a shot after 79 minutes.
A summary of Sunday's action in the Premier League.
Chelsea beat Sheffield United 2-0 to reach the FA Cup semi-finals for the fourth time in five seasons.
Leicester City's Kelechi Iheanacho scored two poacher's goals as they beat Manchester United 3-1 in their FA Cup quarter-final on Sunday to set up a last-four clash against Southampton.
Steven Gerrard scored two penalties as Liverpool went back to the top of the Premier League with a 2-1 win at West Ham United to complete a Merseyside win-double over London clubs on Sunday. Whereas in Bundesliga Sascha Moelders brought an end of the unbeaten run of Bayern Munich.
Wayne Rooney scored twice, the first an astonishing 58-metre volleyed contender for Goal of the Season, as Manchester United won their second game in four days by brushing aside West Ham United 2-0 at Upton Park on Saturday.
Leicester City suffered a frustrating night on the south coast as they were held to a 1-1 draw in the Premier League
Images from the EPL matches played on Boxing Day.
Chelsea will have a massive void to fill in midfield next season after the club's all-time record goalscorer Frank Lampard announced on Monday he was ending his 13-year spell at Stamford Bridge.
Responding to an initiative already run by fans of both clubs, City and United will donate 50,000 pounds each to the Trussell Trust, a support network of more than 1,200 food banks.
Guardiola expects this season's Premier League title race to be more open than last season's
News of all that transpired on and off the football field.
Leicester City striker Jamie Vardy has been charged with improper conduct following his sending off against West Ham United in their 2-2 Premier League draw at the weekend, the Football Association said on Monday.
Leicester City stumbled on their march towards the Premier League title when they drew 2-2 with West Ham United and had goalscorer Jamie Vardy sent off at the King Power Stadium on Sunday.
Chelsea manager Jose Mourinho said he should have brought his Black & Decker drill to break down West Ham United's defensive wall following a 0-0 draw at Stamford Bridge in the Premier League on Wednesday.
Images from the English Premier League matched played on Wednesday.
Images from the English Premier League match between Arsenal and West Ham United on Tuesday.
West Ham United have agreed to sell their ground at Upton Park to London developer Galliard Group once they have moved to the Olympic Stadium in 2016, the club announced on Monday.
Steven Gerrard scored two penalties as Liverpool went back to the top of the Premier League with a 2-1 win at West Ham United to complete a Merseyside win-double over London clubs on Sunday.
Arsenal beat Brighton and Hove Albion 3-2 to reach the FA Cup fifth round.
Images from Sunday's Premier League action.
Third-placed Arsenal tightened their grip on a spot in the top four on the English Premier League table, continuing an impressive run of form at the Emirates with a 3-0 win over West Ham United on Saturday.
High drama ensued during the English Premier League matches on Wednesday as Spurs manager Jose Mourinho was booked while Brighton stunned Chelsea via Alireza Jahanbakhsh's superb equaliser to deny the Blues victory. Here is all the EPL action in IMAGES from Wednesday's matches.
West Ham United piled more misery on managerless Tottenham Hotspur by coming from behind to book their place in the League Cup semi-finals with a 2-1 win at White Hart Lane and Manchester United also reached the last four on Wednesday.
Sunderland and England midfielder Adam Johnson was arrested on Monday on suspicion of having sex with an under-age girl.
Three months after the last ball was kicked, the Premier League emerges from the shadow of the COVID-19 pandemic this week for what will be a 92-match slog to the finish.
Images from the English Premier League matches played on Wednesday night.
Sheffield United players have also agreed to defer wages due to COVID-19 pandemic.
Twelve months ago Liverpool were ripping up the record books on the way to their first English top-flight title for 30 years but defeat by Everton on Saturday left them mulling a host of far less flattering statistics.