Big-hitting American John Isner kept his title defence alive but needed all his experience to see off Canadian teenager Felix Auger-Aliassime 7-6(3), 7-6(4) on Friday to return to the Miami Open final.
Millman, ranked 80 places above world number 14 Pouille, needed 73 minutes to clinch a 6-3, 6-4 victory and the best win of his career by ranking position.
IMAGES from the matches played on Day 10 of the BNP Paribas Open at Indian Wells, California, on Wednesday
Top seed Roger Federer needed less than an hour to dispatch Benoit Paire 6-1, 6-3 and reach the quarter-finals of the Swiss Indoors tournament on Thursday -- treating his home fans to another masterclass.
Ramkumar Ramanathan fetched the crucial win but Yuki Bhambri made the day memorable even in defeat as India and Canada shared the honours on day one of the Davis Cup World Group Play-off tie, in Edmonton.
Images from Day 6 of the Australian Open in Melbourne on Saturday.
That is Murray's 46th ATP title.
World number one Novak Djokovic was sensationally disqualified in the US Open fourth round on Sunday after striking a line judge with a ball following a point during the first set of his match against Spain's Pablo Carreno Busta.
While the year's final grand slam is just underway tennis fans have circled Sept. 8 when, if all goes to form, Nadal and Federer would meet to decide a place in the final.
Nick Kyrgios must not let playing on Rod Laver Arena douse his natural fire when he plays Jo-Wilfried Tsonga in the standout match of the Australian Open third round on Friday, according to former champion Mats Wilander.
But for the first time, that golden trio will be having an anxious glance over their shoulders. The past week in London has revealed a new fearlessness in the generation of 20 somethings expected to fill the void when they call it a day.
Roger Federer used a dominant service game to beat Dutchman Robin Haase 6-3, 7-6(5) in Montreal on Saturday, setting up a Rogers Cup final against German Alexander Zverev.
Serena, a six-times champion in New York who is seeded 17th, will start her campaign against Polish world number 60 Magda Linette and could face Venus in the third round before a possible fourth-round showdown with Romanian top seed Halep.
Roger Federer has paid a glowing tribute to Alexander Zverev, hailing the 20-year-old German as having the 'full package' of skills.
Rafael Nadal is hunting a record-extending and almost unbelievable 12th Roland Garros title is remarkable in itself.
Australian Nick Kyrgios was expelled from the tournament after going wild in the third set of his match against Casper Ruud.
Alexander Zverev is a potential superstar who bears comparison not only with his fellow German Boris Becker but also the great American singer Bob Dylan.
Rafael Nadal suffered a shock 7-5, 6-3 defeat by Austrian Dominic Thiem in the Madrid Open quarter-finals on Friday, a result that means the Spaniard will lose the world number one ranking.
Former world number one Novak Djokovic showed signs of a return to form with an impressive 7-5, 6-4 victory over Japan's Kei Nishikori in the opening round of the Madrid Open on Monday.
Rafael Nadal fired hosts Spain into the Davis Cup final as he joined Feliciano Lopez to win a thrilling late-night doubles and seal a nail-biting 2-1 victory over Britain on Saturday.
Roger Federer gained a measure of revenge against Wimbledon nemesis Kevin Anderson, beating the South African 6-0, 6-4 at the Miami Open on Thursday to set up a mouthwatering semi-final against a player barely half his age.
IMAGES from Australian Open matches played at Melbourne Park on Friday
Images from Day 4 of the 2021 US Open in New York on Thursday.
IMAGES from Day 5 of the 2020 US Open in New York on Friday.
World No. 16 Marco Cecchinato will spearhead Italy's challenge, while they also have the experienced world No. 37 Andreas Seppi as they look to continue their good record against India.
A look at the records of Spain's Rafael Nadal and Serbia's Novak Djokovic before their title clash at the Australian Open on Sunday (prefix number denotes seeding):
A look at the form and records of the four men's semi-finalists at the US Open.
Change might be afoot though, according to American great John McEnroe
With rain having washed out Wednesday's play, Federer along with champion Rafael Nadal and top seed Novak Djokovic all face playing back-to-back matches on Thursday if they want to reach the quarter-finals.
Defending champion Djokovic fired his 15th ace on match point to defeat Querrey but his serve had been an issue earlier in their second-round encounter.
The 33-year-old Swiss, ranked 261 in the world after two knee surgeries, served solidly throughout a one-sided contest on the slick centre court, easing past an opponent who struggled to cope with Wawrinka's power.
Images from Day 10 of the 2021 US Open in New York on Thursday.
Rafael Nadal and Roger Federer will set aside their long-time rivalry when they play for Europe against the rest of the world in the inaugural Laver Cup tournament which starts on Friday.
Images from Day 6 of Wimbledon at the All England Lawn Tennis and Croquet Club in London, on Saturday.
Images from Day 3 of the 2020 US Open in New York, on Wednesday.
Novak Djokovic destroyed a woeful Stefanos Tsitsipas 6-1, 6-2 to book his place in the semi-finals of the Paris Masters.
World number one Rafael Nadal won a battle of attrition against fellow left-hander Yoshihito Nishioka of Japan 7-6(4), 6-4 to seal Spain's spot in the final eight of the inaugural ATP Cup in Perth on Wednesday. Meanwhile his long-time rival, world number two Novak Djokovic, had an easier outing in Brisbane, strolling past Chile's Cristian Garin 6-3, 6-3 to stay undefeated in the new year.
Tennis line judges might grimace when they hear it, but players reacted positively to them being replaced by computerised calls on the opening day of the Next Gen ATP Finals on Tuesday.
Nadal faced no break points in a ruthless display to set up a meeting with Canadian Denis Shapovalov.
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