Aston Villa were crushed 6-1 by Southampton but joined Leicester City in celebrating Premier League survival on Saturday while Steven Gerrard's farewell party was spoiled as Liverpool lost 3-1 to Crystal Palace.
Holders Real Madrid breezed into the last 16 of the Champions League with two games to spare when a Karim Benzema strike secured a 1-0 win in their Group B match at home to a toothless Liverpool on Tuesday.
Arsenal delivered a brutal lesson in fast-paced Premier League football to beat Liverpool 4-1 on Saturday, maintaining their faint title aspirations and almost certainly dashing their opponents' hopes of a top-four finish.
Liverpool added another fairytale comeback to the history books as they fought back from 3-1 down against Borussia Dortmund to reach the Europa League semi-finals after Dejan Lovren's towering stoppage-time header secured a 4-3 win on Thursday.
Liverpool's 1-0 defeat by Aston Villa on Saturday was more than an early season setback - it raised the question of whether they have the strength in depth to cope with the dual challenge ahead of them this term.
A summary of Tuesday night's matches in the UEFA champions League.
Images from Champions League matches played across Europe on Tuesday
Chelsea moved within touching distance of a first Premier League title in five years with a 1-0 win over Manchester United while Lionel Messi reached a landmark with his 400th career goal for La Liga leaders Barcelona.
The three teams with 100 percent records in this season's Champions League can secure their places in the knockout stage this week with two games to spare.
'Keep Calm And Carry On' could be Claudio Ranieri's motto for the second half of the season after Leicester City earned a 1-0 win at Tottenham Hotspur on Wednesday to put the heat back on Premier League leaders Arsenal.
Cristiano Ronaldo bagged his first five-goal haul in Real Madrid's 9-1 hammering of Granada while title-chasing Bayern Munich and Chelsea won again in Germany and England.
Mesut Ozil helped Arsenal shake off the hangover of a midweek pounding in Germany with a starring role in a 3-0 win at Aston Villa while sloppy Liverpool lost 3-1 at West Ham United in the Premier League on Saturday.
After five years away, Champions League drama returned to Anfield like a long lost friend on Tuesday as Liverpool beat debutants Ludogorets of Bulgaria 2-1 with Steven Gerrard scoring a last-gasp penalty.
A summary of the results of the major European football league matches on the weekend.
Spoils were shared in two huge Premier League derbies, Chelsea's cracking start continued with a 3-0 win over Aston Villa and Wayne Rooney produced a Jekyll and Hyde display in a nervy Manchester United victory on Saturday.
Spoils were shared in two huge Premier League derbies, Chelsea's cracking start continued with a 3-0 win over Aston Villa and Wayne Rooney produced a Jekyll and Hyde display in a nervy Manchester United victory on Saturday.
Arsenal and Manchester City meet at The Emirates on Saturday when both teams will seek to roar into life after making spluttering starts to their Premier League campaigns.
Arsenal maintained their challenge for a first trophy in nine seasons when they beat Liverpool 2-0 at the Emirates Stadium to open up a five-point lead at the top of the Premier League on Saturday.
Jose Mourinho got the better of old adversary Arsene Wenger once again as Chelsea showed their strength-in-depth by reaching the League Cup quarter-finals with a 2-0 win over London rivals Arsenal on Tuesday.
Real Madrid earned their first-ever win over Liverpool with a wondrous Cristiano Ronaldo goal spearheading a 3-0 Champions League victory at Anfield on Wednesday which appeared as classy as it was dominant.
Dejan Lovern talks about his ambition to become a Liverpool legend at Anfield and why victory in the Merseyside derby against Everton could propel Reds' chances this season.
The ATP issued the latest men's tennis rankings on Monday and the top 10 list remains unchanged with Serbian tennis ace Novak Djokovic still leading the rankings.
Angel di Maria's move from Real Madrid to Old Trafford was such a disaster that Manchester United was more than willing to incur losses of more than 15 million pounds on their investment. Bikash Mohapatra/Rediff.com looks at the Argentina star's nightmare year at the 'Theatre of Dreams'.
The 20-time English Premier League champions are far from their best, but, in the final analysis, it is the results that matter, and at the moment they are on a winning spree, says Bikash Mohapatra
Rediff.com brings the latest news on English Premier League, results, and transfers around the world of soccer.
Cristiano Ronaldo renewed his personal battle with Lionel Messi by scoring his 71st Champions League goal, putting him three behind the Argentine's newly-set record, in Real Madrid's 1-0 win at FC Basel on Wednesday.