Barcelona signed Arsenal's Belgium international defender Thomas Vermaelen on a five-year contract on Sunday.
Finland, who came third with three points, must wait until the end of the group stage to see if their adventure in a first ever major tournament will continue and they need a series of results to go their way if they are to make the last 16.
Barcelona said captain Iniesta would miss the match after he was not able to train with his team mates on Tuesday ahead of the encounter at the Santiago Bernabeu, where the Catalans will look to overturn a 3-1 deficit.
Arsenal's squad are keen for manager Arsene Wenger to sign a new contract with the English Premier League title chasers and lead them for many years to come, said captain Thomas Vermaelen.
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Belgium's superior experience outsmarted the Finns' dogged defending.
'We would prefer to play home games. That would be an advantage, that you do not travel. The other countries we play against play home games. That is a shame for us but we have to accept the situation as it is.'
Arsenal suffered a humiliating League Cup quarter-final exit to fourth tier Bradford City on Tuesday, losing 3-2 on penalties after an absorbing game finished 1-1 at the end of extra time at a packed Valley Parade.
Former winners Borussia Dortmund host Arsenal in their Champions League Group F opener on Tuesday, with both sides desperate to drag themselves out of an early slump this season.
Arsenal narrowed the gap on third-placed Tottenham Hotspur to one point when Thomas Vermaelen struck deep in stoppage time to seal a 2-1 win over Newcastle United in a dramatic Premier League match on Monday.
Eden Hazard has suffered a knock and is expected to return to training for Belgium after limping out of their behind-closed-doors session on Friday, coach Marc Wilmots said.
Arsenal bounced back from two successive Premier League defeats in emphatic style by thrashing Wigan Athletic 4-0 at the Emirates on Saturday.
Arsenal's Eduardo da Silva, playing two days after his diving ban was lifted on appeal, celebrated his reprieve by scoring a late winner in a dramatic 3-2 Champions League win at Standard Liege on Wednesday. The Brazilian-born Croatia striker netted from close range with nine minutes to go, three minutes after Thomas Vermaelen had levelled for the Londoners.
Arsenal defender Thomas Vermaelen suffered a suspected broken leg during the goalless draw at Aston Villa in the Premier League on Wednesday.
Arsenal fought back from 2-0 down to beat Bolton Wanderers 4-2 and go top of the Premier League while Liverpool re-ignited their season with a 2-0 win over Tottenham Hotspur on Wednesday.
Chelsea regained their dominant place in the Premier League title race with a 3-0 win over Arsenal at the Emirates on Sunday that restored their five-point lead over Manchester United.
Fernando Torres scored twice as Liverpool battled to a 3-2 English Premier League win at West Ham United on Saturday after the Londoners had twice pegged them back. Belgian centre back Thomas Vermaelen was a less likely two-goal hero as his double set up Arsenal for a 4-0 home thrashing of Wigan Athletic - emphatically avoiding a hat-trick of defeats after losses to Manchester United and City.
A superb second-half strike from Adnan Januzaj gave Belgium a 1-0 win over England on Thursday to see them top World Cup Group G with a perfect record and consign England to second place, with both sides already assured of going through to the last 16.
Barcelona coach Luis Enrique has decided to rest Lionel Messi, Neymar and most of his regulars for the King's Cup last 16, second leg match at Elche later on Thursday.
Barcelona midfielder Andres Iniesta has failed to recover from a calf strain and will miss Tuesday's Champions League Group F match at APOEL Nicosia.
Arsenal forward Lukas Podolski could be ruled out for up to 10 weeks with a hamstring injury, manager Arsene Wenger said on Thursday.
Gijon spoiled Asier Illarramendi's return to Real Sociedad's midfield after rejoining from Real Madrid this week when they held the Basque club, coached by Scot David Moyes, to a 0-0 draw in San Sebastian.
Barcelona coach Luis Enrique believes his current squad is the strongest he has ever had and he is very confident of retaining the La Liga and King's Cup titles. The Spanish champions have recruited Andre Gomes, Samuel Umtiti, Lucas Digne and Denis Suarez since the end of last season while Marc Bartra, Thomas Vermaelen, Adriano Correia and Sandro Ramirez have departed. "On paper, this is the best squad that I have had in my three years at Barca," Luis Enrique told the club's website. "We have a squad that has been strengthened brilliantly.
Central defender Thomas Vermaelen is mulling the prospect of leaving Arsenal in January to boost his chances of playing for Belgium in the World Cup finals.
The midfield duo, who both have dual Moroccan-Belgian nationality, kept Belgium alive with their goals off the bench in the extraordinary round of 16 comeback against Japan and were handed starts in the 2-1 win over Brazil.
Belgium coach Roberto Martinez declared himself delighted with a 3-0 win over World Cup debutants Panama but there were plenty of issues that will encourage England after their own winning start in Group G.
Defensive injury concerns for veteran squad leader Vincent Kompany and Barcelona's Thomas Vermaelen have eased and coach Roberto Martinez has sent standby defender Laurent Ciman home.
A third place finish at the World Cup on Saturday leaves a strong legacy for Belgian football, coach Roberto Martinez said
La Liga champions Barcelona slumped to a shock 2-1 defeat at struggling Leganes and Real Madrid were resoundingly beaten 3-0 by Sevilla on Wednesday as Spain's two biggest clubs lost on the same day for the first time since January, 2015.
Divock Origi's late strike earned Belgium a 1-0 Group H win over Russia at the Maracana Stadium on Sunday to seal a spot in the knockout round of the World Cup.
Marcelino dismissed but Valencia keep pressure on Barcelona
Belgium hammered the final nail into Egypt's halting World Cup warm-up campaign with an assured 3-0 win in Brussels on Wednesday that settled some nerves among the fancied hosts.
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Luis Suarez has progressed from his impressive debut La Liga campaign to produce the most prolific season of his career and fire Barcelona to a second straight title, free of the stigma of his ban for biting which accompanied him to Spain in 2014. It was fitting that the Uruguayan should score a hat-trick in the comfortable 3-0 victory at Granada on Saturday to clinch the title, taking his tally to 40 goals in 35 games. He is the first player other than Cristiano Ronaldo and Lionel Messi to finish as La Liga top scorer since 2009 but his contribution to Barca's title triumph goes beyond his goals and 16 assists. For Suarez is the hardest working of the feted 'MSN' partnership he forms with Messi and Neymar, a trio who have delivered 90 of Barcelona's 112 league goals. He is also the most willing to close down opponents and run into space and, naturally, he has shown himself to be the player who is keenest to throw himself into any physical battle.
Barcelona defender Gerard Pique fears his side's shock elimination from the Champions League could disturb their bid to retain the La Liga title as they host Valencia on Sunday looking for a first win in four league games.
Last season's treble winners Barca are in their worst run of form in La Liga since coach Luis Enrique took charge in August 2014.
Zoo director Vladimir Gerasimov believes Cleopatra might have a little better understanding of soccer than other animals.
Wales's Euro 2016 victory over Belgium, officially the second-best team in football, showed again that you can have all the attacking talent in the world but if you are weak at the back you will be found out at the highest level.
With most Manchester United fans praying for much-needed defensive reinforcements, manager Louis van Gaal made a surprise deadline-day swoop for flamboyant Colombian striker Radamel Falcao on Monday.
Belgium have retained injured Vincent Kompany in their final World Cup squad but put fellow defender Laurent Ciman on standby in case the Manchester City skipper is not fit for their opening match in Russia.
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