Nadal faced no break points in a ruthless display to set up a meeting with Canadian Denis Shapovalov.
Marin Cilic and Milos Raonic booked their spots in the Paris Masters second round on Monday, while Roger Federer pulled out of the tournament with next month's ATP Finals on the horizon.
Defending champion Donna Vekic, of Croatia, earned a hard-fought win over British wild card Gabriella Taylor 7-5, 5-7, 7-6(3).
Images from Day 9 of the 2021 French Open at Roland Garros in Paris on Monday.
Summary of sports events and persons who made news on Thursday
Images from Day 6 of Wimbledon at the All England Lawn Tennis and Croquet Club in London, on Saturday.
Summary of sports events and persons who made news on Tuesday
A summary of the action on Day 3 at the US Open.
Greek teenager Stefanos Tsitsipas slayed another tennis giant on Saturday, saving a match point as he toppled big-serving Kevin Anderson 6-7(4), 6-4, 7-6(7) in a thriller to set up a Rogers Cup final against top seed Rafael Nadal.
Alexander Zverev got the better of older brother Mischa at the Citi Open in Washington on Thursday, winning their first meeting at an ATP Tour event 6-3, 7-5.
It was a triumphant return to the tour for Djokovic
Ash Barty beat eighth seed Kiki Bertens of the Netherlands 6-3, 3-6, 7-6(7) in Beijing to seal her spot in the final of the China Open on Saturday.
After a brief interruption when the players were locked at 5-5 in the opening set, Federer saved two set points in the tiebreak and held firm to gain the upper hand in the contest.
Here are eight men to watch on the Roland Garros clay.
Images from Day 1 of the US Open in New York, on Monday.
Laslo Djere won his first ATP title at the Rio Open on Sunday and then captured the hearts of the Brazilian crowd with a victory speech dedicated to his parents, both of whom died from cancer.
Novak Djokovic and Rogerer Federer loom over Melbourne Park for the year's opening Grand Slam as favourites for the Australian Open as questions remain as to whether one of Generation Next could finally end their stranglehold.
Venus Williams staged a spirited comeback to down third seed Petra Kvitova 4-6, 7-5, 6-4 and reach the third round of the BNP Paribas Open in Indian Wells on Saturday.
Top seeded Ash Barty overcame a slow start to defeat Maria Sharapova 6-4 6-1, while Simona Halep battled past Ekaterina Alexandrova 3-6 7-5 6-4 in the second round of the Cincinnati Masters on Wednesday.
Earlier on Wednesday, Czech Karolina Pliskova was forced to withdraw from the tournament due to a viral illness.
India ended its campaign at the Fed Cup with a fourth place finish after losing the classification tie 1-2 to Korea as the team badly missed injured Karman Kaur Thandi, who did not play on Saturday, in Astana, Kazakhstan.
It was Kristyna's first win over a top-five ranked player and she will go on to play fellow Czech Barbora Strycova in the quarter-finals.
The Russian five-times Grand Slam champion struggled for rhythm initially on the low-bouncing grasscourt at the Mallorca Open but picked up the pace to beat Viktoria Kuzmova 7-6(8), 6-0.
Rafael Nadal extended his astonishing winning run on clay to 42 consecutive sets as he reached the semi-finals of the Barcelona Open with a 6-0, 7-5 victory over Slovakia's Martin Klizan on Friday. The defending champion will face David Goffin on Saturday after the Belgian beat Spaniard Roberto Bautista 6-7(3), 6-2, 6-2.
Top seed Dominic Thiem was knocked out the Rio Open in the first round on Tuesday, going down 6-3, 6-3 to Laslo Djere.
Second seed Sloane Stephens was shocked 2-6, 6-4, 6-2 by Germany's Andrea Petkovic in the second round of the Citi Open on Wednesday, disrupting the American's buildup to her US Open title defence.
IMAGES of the all the action from Day 1 of the Australian Open played at Melbourne Park on Monday
The last 10 Slams have all been won by Djokovic, Federer or Nadal. Will this Wimbledon be different, asks Dhruv Munjal.
She is the second Swiss player to win the tournament after Martina Hingis won the inaugural edition in 2001.
Summary of sports events and persons who made news on Tuesday
A summary of the second day's play at the US Open.
Rafael Nadal was made to wait before his second-round Rogers Cup match due to several rain delays but did his part to put the schedule back on track with a speedy 6-2 6-3 win over Frenchman Benoit Paire on Wednesday.
Czech defending champion Katerina Siniakova fended off Maria Sharapova in a fiercely contested match at the Shenzhen Open on Friday to set up a final with world number one Simona Halep.
Roger Federer rallied from a set down to beat Moldovan surprise package Radu Albot 4-6, 7-5, 6-3 in a stuttering start to the 20-times Grand Slam champion's Miami Open campaign on Saturday.
The Swiss great is looking to win a 102nd tour-level trophy and move closer to Jimmy Connors' record of 109.
The Scot lost 6-4, 6-4 to Richard Gasquet in his first singles match since January before saying he had turned down a wild card into the men's draw at the year's final Grand Slam.
Images from Day 8 of the Australian Open in Melbourne on Monday.
The 32-year-old, five-times a winner of the singles at the prestigious Wimbledon warm-up event, delighted a large evening centre court crowd with some fluent shot-making as he and Spanish veteran Lopez beat top seeds Juan Sebastian Cabal and Robert Farah 7-6(5), 6-3.
A summary of sports events and sports persons, who made news on Thursday
Serbian Djokovic, 31, needed elbow surgery in February to cure a problem that surfaced in 2017, but after some jarring defeats he returned to the kind of domination he achieved in 2015, winning Wimbledon and the US Open.