La Liga champions Barcelona began the new campaign with a 3-0 win over Alaves on Saturday with the help of a spectacular under-the-wall free kick from Lionel Messi, who scored twice, and a curling shot from substitute Philippe Coutinho.
Chelsea returned to their early-season form to open up a five-point lead in the Premier League, Cristiano Ronaldo and Lionel Messi continued to make mincemeat of La Liga defences and Juventus extended their lead in Serie A. In France, Olympique Lyonnais retained top spot with a 2-0 win at RC Lens.
Real Madrid coach Carlo Ancelotti will discuss his future with the club after Saturday's final La Liga game of the campaign at home to Getafe and said he wants to stay on despite a season without a major trophy.
Casemiro headed an 89th minute winner to earn Real Madrid a barely deserved 2-1 victory at Las Palmas in La Liga on Sunday as they closed the gap on second-placed Atletico Madrid to four points.
Real Madrid have defied injuries to keep the pressure on leaders Barcelona and notched up over 100 La Liga goals but they now face arguably the toughest test of their title charge in an away match to Sevilla on Saturday.
Goals from Karim Benzema and Jese led Real Madrid to a 2-0 win over Osasuna in their King's Cup last-16 first leg at the Bernabeu on Thursday.
Valencia's Paco Alcacer, Dani Parejo and Pablo Piatti found the target as they took full advantage of the first-half dismissal of Malaga's Sergi Darder to win 3-0 at the Mestalla on Friday.
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Neymar struck twice as Barca beat Atletico Madrid to reach the King's Cup semis
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Real Madrid kept alive their hopes of overhauling La Liga leaders Barcelona when a James Rodriguez stunner set them on their way to a serene 3-0 home victory over struggling Almeria on Wednesday.
Ballon d'Or winner Cristiano Ronaldo scored the opening goal as 10-man Real Madrid beat Osasuna 2-0 on Wednesday to qualify for the King's Cup quarter-finals 4-0 on aggregate.
Second-half headers from Diego Godin and Raul Garcia gave holders Atletico Madrid a 2-0 win over Valencia and a place in the King's Cup quarter-finals by 3-1 on aggregate.
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Lionel Messi will be working "full time" to shake off the hamstring injury sustained on Sunday that will sideline him for six to eight weeks, Barcelona's Argentine World Player of the Year said on Tuesday.
Cristiano Ronaldo hit a late double as La Liga leaders Real Madrid thumped Almeria 4-1 to extend their Spanish record for consecutive victories in all competitions to 20.
Villarreal continued their impressive revival after a season in the second division when Jeremy Perbet and Jonathan Pereira struck in a 2-1 win at home to Espanyol in La Liga on Thursday.
Now, Real Madrid have never won the Spanish treble and are fighting tooth and nail in La Liga to prevent arch-rivals Barcelona scooping Champions League and domestic league and Cup titles for a second time.
Raheem Sterling struck twice as the Premier League champions Manchester City beat Crystal Palace 3-1 at Selhurst Park on Sunday to stay within two points of leaders Liverpool.
Real Madrid included Denis Cheryshev in their starting lineup for their first match of the 2015-16 competition even though he should have been serving a one-match suspension and the Russia forward opened the scoring in a 3-1 victory.
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Real Madrid top scorer Cristiano Ronaldo has signalled strong support for coach Carlo Ancelotti and sent a clear message to club president Florentino Perez that he does not want the Italian to be sacked.
Barcelona made a brisk start to the season with new coach Luis Enrique at the helm in place of Gerardo Martino and a host of additions to the squad, including midfielder Ivan Rakitic and goalkeeper Claudio Bravo.
Atletico Madrid kept pace with leaders Barcelona and restored their five-point lead over third-placed city rivals Real when Diego Costa and David Villa each scored a penalty in a 2-1 win at Granada in La Liga on Thursday.
News of all that's transpired on and off the football field
News of all that's transpired on and off the football field
This and more from the happenings in the world of football
Barcelona seized control of their King's Cup quarter-final tie against Atletico Madrid when Lionel Messi followed up his saved penalty to score and secure a 1-0 first-leg victory at the Nou Camp on Wednesday.
Lionel Messi dragged Barcelona back from two goals down by scoring twice to snatch a 2-2 draw at home to Valencia in a thrilling encounter.
Manchester City swept aside second-tier Cardiff City 2-0 with first-half goals from Kevin De Bruyne and Raheem Sterling on Sunday to reach the FA Cup fifth round in their quest to win an unprecedented four trophies this season.
Barcelona's Lionel Messi was at the heart of another devastating attacking show.
A summary of the results of the major European football league matches on the weekend.
Fernando Torres stole the show with a dramatic double as Atletico Madrid secured a battling 2-2 draw at Real Madrid on Thursday that dumped the holders out of the King's Cup 4-2 on aggregate.
Real Madrid secured a club record 16th straight victory when Karim Benzema and Gareth Bale struck in a laboured 2-1 win at Malaga on Saturday that put them five points clear of second-placed Barcelona in La Liga.
Check out the top footballers of the weekend...
Barcelona's stuttering title bid suffered another setback when they lost 2-1 at home to Valencia on Sunday, while Atletico Madrid moved level on points with the La Liga leaders after a comfortable win over Granda.
Barcelona eased into the King's Cup last 16 when goals from Pedro, Cristian Tello and Neymar secured a 3-0 second-leg victory at home to third-tier Cartagena on Tuesday for a 7-1 aggregate success.
Valencia climbed above Atletico Madrid and Sevilla into third in La Liga when Alvaro Negredo came off the bench to score a late winner in a 3-2 home victory over his former club Almeria on Saturday.
Lionel Messi overhauled Real Madrid great Alfredo Di Stefano's La Liga goals tally as Barcelona and Atletico Madrid each won on Saturday to pull three points clear of Real at the top.
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