Dortmund now have 14 points, one ahead of champions Bayern Munich, who suffered their first defeat of the season on Friday with a 2-0 loss at Hertha Berlin.
Bayern Munich eased into the German Cup semi-finals with a 3-0 victory over 10-man VfL Bochum on Wednesday with Robert Lewandowski scoring twice to keep their treble hopes on track.
In the other pairings, English champions Manchester United will take on Greek club Olympiakos, while AC Milan take on Atletico Madrid.
A round-up of Tuesday's action in the UEFA Champions League.
Bayern Munich came from a goal down to ease past hosts Bayer Leverkusen 4-2 on Saturday and remain firmly on course to retain the Bundesliga title with four games remaining. The Bavarians are within touching distance of their eighth consecutive league crown, but Leverkusen's 17-year-old Florian Wirtz stole some of the spotlight at the end, becoming the youngest Bundesliga scorer when he netted in the 89th minute.
Harry Kane scored twice in his first league appearance in front of a home crowd to steer champions Bayern Munich to a 3-1 victory over Augsburg.
Images from football matches held across Europe on Saturday
A round-up of Saturday's action in La Liga and the Bundesliga.
Barcelona eased into the Champions League quarter-finals with a 4-1 aggregate victory over Manchester City on Wednesday and Paris St Germain joined them after overwhelming Bayer Leverkusen 6-1 over the two legs of their last-16 tie.
Arsenal will have another chance to beat Bayern Munich in a Champions League knockout tie after the sides were paired in the round of 16 following Monday's draw. The teams met in the knockout stages in 2005, 2013 and 2014 with the German champions winning on all three occasions. Bayern, who finished as runners-up in their group, will host the first leg.
LaLiga leaders Barcelona's pursuit of a 27th Spanish title gained momentum after a 2-1 comeback win over Real Madrid.
Real Madrid's Cristiano Ronaldo set a Champions League group phase scoring record on Tuesday as Bayer Leverkusen and Olympiakos Piraeus reached the last 16 and snow forced Galatasaray's match with Juventus to be abandoned.
Manchester United's veteran midfielder Ryan Giggs was outstanding in a commanding midfield role as United outclassed the Germans to book their place in the knockout phase of the Champions league.
Real Madrid, Manchester United and Paris St Germain reached the last 16 of the Champions League on Wednesday on a night when the goals flowed all over Europe.
All the latest news from the summer transfer window...
Daniel Sturridge led Liverpool to a great win over Swansea while Gareth Bale helped Real Madrid to go top of the La Liga table, after shock defeats of Barcelona and Atletico Madrid, with a 3-0 win over Elche at the weekend. Chelsea clung to top place in the Premier League with a 1-0 win over Everton, while Bayern Munich opened a 19-point lead in the Bundesliga with their 14th successive league win while closest rivals Bayer Leverkusen and Borussia Dortmund lost. Rediff.com brings you a glance of the footballers of the weekend.
Cristiano Ronaldo's hat-trick for Real Madrid illuminated an opening night goals bonanza as the leading contenders began the Champions League group stage with a bang on Tuesday.
Manchester United breezed into the next round with a 6-1 aggregate win over Club Brugge
The teams finished level at 3-3 on aggregate in the tie but the Lisbon club advanced to the quarter-finals after Adan kept out Martinelli's weak effort.
Chelsea manager Frank Lampard believes his side are a long way short of the levels of Premier League Champions Liverpool and Manchester City, who have set the benchmark in terms of consistency. Lampard's Chelsea, currently third in the league, visit title winners Liverpool on Wednesday, chasing the three points they need to secure Champions League football next season.
Former Germany captain Michael Ballack's farewell match in Leipzig on Wednesday was overshadowed by the potential transfer of Andre Schuerrle to Chelsea with German media reporting a deal has been agreed.
Inter Milan and Bayer Leverkusen cruised into the Europa League knockout stage with emphatic wins on Thursday but holders Atletico Madrid and former winners Liverpool suffered surprise defeats.
Wayne Rooney scored twice against Bayer Leverkusen on Tuesday to reach 200 Manchester United goals as he enjoys a new lease of life under David Moyes who thinks he can become one of the club's greatest predators.
Wayne Rooney scored twice against Bayer Leverkusen to reach 200 Manchester United goals as he enjoys a new lease of life under David Moyes who thinks he can become one of the club's greatest predators.
Christian Pulisic has had a season to forget for Chelsea but in the blue shirt of his beloved United States he scored the goal that gave them their first win at the 2022 World Cup and a spot in the last-16.
A wrap of the football matches played across Europe over the weekend.
Seven-time European champions AC Milan hit back from two goals down against Celtic to claim a 4-2 victory that sent them into the Europa League knockout phase on Thursday as they were among 14 teams to progress in Europe's second-tier competition.
Bundesliga champions Bayern Munich suffered their first league defeat in 18 months when they slumped to a 1-0 loss at Augsburg on Saturday as Sascha Moelder's first-half strike ended their record 53-game unbeaten league run.
Lionel Messi's knack for finding the net continued for an 18th consecutive league match as Barcelona restored their 13-point lead in La Liga.
Soccer in Germany has been suspended for almost a month and the German Football League (DFL) has said the ban will remain in place for the top divisions at least until April 30. Clubs, however, were given the all clear to resume training this week, with champions Bayern Munich deciding to train players in small groups to minimise the risk of infection.
Bayern Munich demolished Schalke 04 4-0 with two goals from David Alaba to open a 15-point gap at the top of the Bundesliga on Saturday as champions Borussia Dortmund and Bayer Leverkusen slipped up.
Holders Bayern Munich beat Bayer Leverkusen 5-3 on penalties after a 0-0 draw to move into the German Cup semi-final and stay on course for a treble of titles on Wednesday.
The hosts could have snatched victory in the last action of the game but Michael Gregoritsch's point-blank header was saved by Lukas Hradecky.
Gladbach dominated the first half and missed a string of chances, with Freiburg goalkeeper Alexander Schwolow denying Plea and Lars Stindl in quick succession as the home side defended desperately.
Bayern Munich retained their two-point lead at the top of the Bundesliga with a nervous 3-1 victory against Mainz 05 on Saturday as champions Borussia Dortmund kept up the chase with a 3-0 win over Bayer Leverkusen.
Robert Lewandowski struck twice as champions Bayern Munich eased past Freiburg 3-1 on Saturday to secure a record 15th win in a row and the Pole became the first foreign player to score 33 goals in a Bundesliga season. Erling Haaland scored twice as Borussia Dortmund beat closest challengers RB Leipzig 2-0 away on Saturday to wrap up second place in the Bundesliga.
Mario Mandzukic scored one goal and created the other as Bundesliga leaders Bayern Munich pulled 11 points clear of their nearest title rivals with a 2-0 victory at VfB Stuttgart on Sunday.
Women's Bundesliga can restart on May 29, says the German Football Association (DFB).
Former Germany captain Michael Ballack announced his retirement at the age of 36 on Tuesday to end a career in which he played for Bayern Munich and Chelsea and helped his country reach the 2002 World Cup final.
If two or more clubs are level on points at the end of the group stage, a number of criteria will be taken into consideration to decide the qualifiers for the next round, starting with the head-to-head record among the teams in question. It then goes to superior goal difference and then goals scored in those matches.
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