Second-placed Sevilla were held to a 1-1 draw by Barcelona, while Juventus registered a routine 2-0 win over struggling Cagliari.
'They were better than us for some spells and we know what awaits us over there' Valverde pointed to his team's sensational exit from last year's competition to AS Roma after a 4-1 cushion from the first leg and said they would be taking nothing for granted in Tuesday's return game at Anfield.
Immobile strikes in Lazio's win, in contention for golden boot. IMAGES from the Serie A matches played on Wednesday.
AS Roma needed a penalty from 40-year-old forward Francesco Totti in the seventh minute of stoppage time to scrape past second-tier Cesena 2-1 in their Coppa Italia quarter-final on Wednesday.
Juventus were given a chance to avenge last year's Champions League final defeat by Real Madrid when they two sides were drawn together for the quarter-finals of this year's competition on Friday.
Ronaleo netted his 14th league goal for Juve this season while PSG's winning streak was snapped by Monaco in a 3-3 draw. Here are images from the matches played on Sunday
Bruno Fernandes and Edinson Cavani scored twice each as Manchester United took a giant step towards the Europa League final with a 6-2 drubbing of AS Roma in their semi-final first leg at Old Trafford on Thursday.
Evergreen Francesco Totti, in his 22nd season with AS Roma, scored his first goal of the new campaign to give help them to a 3-1 win at Parma which maintained their 100 percent record in Serie A.
The three Premier League and three La Liga clubs in the last eight avoided each other, with Manchester City up against Atletico Madrid and Liverpool to face Portuguese side Benfica.
Juventus substitute Cristiano Ronaldo was denied a stoppage-time winner by VAR as Udinese came from two goals down to snatch a 2-2 draw in their thrilling Serie A season opener on Sunday.
The Liverpool forward was rewarded for his performances which have yielded 41 goals in all competitions since joining from AS Roma last year.
The much-travelled Ranieri won the Premier League title with unfancied Leicester City in 2016 and most recently coached French side Nantes.
Liverpool manager Juergen Klopp admitted they needed luck to get past AS Roma in the second leg of their Champions League semi-final on Wednesday after old defensive issues reared their head.
Cristiano Ronaldo continued from where he left off in the early stages of the UEFA Champions League, adding to his goal tally as Real Madrid beat AS Roma 2-0 in their round of 16, first leg tie on Wednesday.
Marseille cement second place with Montpellier win
Germany forward Mario Gomez, scorer of only one Serie A goal this season, struck twice in the first half hour to help Fiorentina beat Atalanta 3-1 in the Italian Cup on Wednesday.
AS Roma suffered another European humiliation on Tuesday when they had two players sent off, lost 3-0 at home to Porto and missed out on the Champions League group stage.
Pep Guardiola's ManchesterCity will play Romanian side Steaua Bucharest in the Champions League playoff round after the draw was made in Nyon on Friday.
Juventus won Serie A for the fifth season in a row without kicking a ball on Monday after Napoli, the only team who could have caught them, were sunk 1-0 by a late Radja Nainggolan goal at AS Roma. Juventus, who have led the table since beating Napoli 1-0 in February, were left with an unassailable 12-point lead with three games each left to play as they clinched a record 31st league title. The match, played at a half-empty Stadio Olimpico on a sunny bank holiday afternoon, was an anti-climatic end to a season which had at one stage promised to be one of the most exciting Italian title races for years. The game between Serie A's two highest-scoring sides was threatening to peter out into a tame goalless draw until Nainggolan slotted the ball home in the 89th minute following a move started with a delicate pass from Roma substitute Francesco Totti.
AC Milan grabbed a 1-1 draw at Manchester United in the blockbuster Europa League last-16 first-leg at Old Trafford on Thursday.
Holders FC Barcelona have been placed in Group E, along with Bayer Leverkusen, AS Roma, Dinamo Zagreb.
Francesco Totti scored a late penalty in AS Roma's 2-1 win over Cagliari to deny Inter Milan the chance to win the Serie A title with a game to spare on Sunday.
News of all that's transpired on and off the football field
Paris St Germain extended their Ligue 1 lead to 13 points with a 4-3 home victory against Girondins de Bordeaux on Sunday but the French champions were again exposed at the back and had Neymar sent off. A Marquinhos double, Edinson Cavani's 200th PSG goal and a goal by Kylian Mbappe put the capital side on 65 points from 26 games but they lost captain Thiago Silva to a muscle injury and Neymar picked up a straight red card for a late challenge in stoppage time.
Serie A leaders Inter Milan failed to capitalise on the draw between closest rivals AC Milan and AS Roma when they were held 0-0 by Genoa at the San Siro on Sunday.
Italy's top sports body on Monday called for all sports events to be cancelled until April 3, and asked the government to issue a decree to enforce the measure as the country fights with the worst coronavirus outbreak in Europe.
Former Brazil and Inter Milan striker Adriano could be the latest high-profile footballer to join Indian Super League.
Harry Kane netted his 200th goal for Tottenham Hotspur as they won 3-1 at Ludogorets and AC Milan's 24-match unbeaten run ended
Fiorentina captain and defender Davide Astori died of a sudden illness on Sunday morning, the Italian Serie A club said.
AS Roma qualified for the Champions League group stage in the best possible style on Monday, booking their place with a last-gasp 2-1 win over neighbours and bitter rivals Lazio in a passionate Rome derby.
Real Madrid coach Zinedine Zidane reckons Cristiano Ronaldo is on top form as the Portuguese looks to increase his Champions League goals tally when they visit AS Roma in the first leg of their last-16 tie on Wednesday.
Cristiano Ronaldo converted two penalties as he scored for the ninth Serie A game in a row on Sunday to give Juventus a somewhat flattering 3-0 win over Fiorentina which kept them top of Serie A.
Gareth Bale ended a three-month goal drought in La Liga to give Real Madrid a nervy 1-0 win away to basement club Huesca on Sunday, taking his side back into the top four at the expense of Alaves.
Girondins Bordeaux ended the unbeaten Champions League run of surprise package CFR Cluj with a 1-0 win over the Romanian side.
News of all that's transpired on and off the football field
Inter Milan got a crucial 1-0 win at Juventus on Sunday
Images from Sunday's action in La Liga, Serie A and Ligue 1.
Serie A soccer matches in the northern Italian regions of Lombardy and Veneto will not be played on Sunday because of an outbreak of the coronavirus, the government said in a statement. The three impacted fixtures are clashes between Inter Milan and Sampdoria, Atalanta against Sassuolo and Hellas Verona against Cagliari. Italy is tackling the worst outbreak of coronavirus yet recorded in Europe, with two people dying in the north since Friday and nearly 60 infected.
IMAGES from Europa League matches played on Thursday.
Ronaldo, who won the award last year, topped the scoring charts with 15 goals in the competition as Real Madrid won a third consecutive European crown.