Champions Leicester City's alarming slump continued with a 3-0 Premier League defeat at Southampton on Sunday that left them just five points off the drop zone and firmly embroiled in a relegation fight.
Manchester United battled back from two goals down to beat Newcastle United 3-2 at Old Trafford on Saturday as a 90th-minute winner from Alexis Sanchez completed a spirited comeback to ease the pressure on manager Jose Mourinho.
Brighton and Hove Albion's Tomer Hemed grabbed the only goal as they ended Newcastle United's three-match winning streak with a 1-0 victory on Sunday in a battle between two of this season's promoted sides.
'The mental level, the day by day, everything must be consistent until the last day so one of the things we have to improve is consistency'
Liverpool manager Juergen Klopp acknowledged that they would have to defend better in the visit to Stamford Bridge to stop Eden Hazard reprising the sort of solo brilliance that propelled Chelsea to victory at Anfield on Wednesday.
'It's very difficult to play football in these circumstances within 48 hours. It's amazing for the fans around the world, everybody has the Premier League, I'm more than happy to do that but it's very hard for the players'
Manchester United manager Jose Mourinho has dismissed suggestions that midfielder Paul Pogba faces a lengthy lay-off because of a hamstring injury sustained in the Champions League defeat of Basel on Tuesday.
Tottenham went ahead through Sanchez who scored his first goal for the London club by meeting Eriksen's whipped cross with a diving header in the 33rd minute, although Leicester's players complained he was in an offside position.
Chelsea lost their 100 per cent Premier League record when London rivals West Ham United held them to a 0-0 draw on Sunday.
Images from the English Premier League matches played on Saturday
The centre-back has not played since Sarri took over from Antonio Conte at the start of the season, and says he could call time on his career at Stamford Bridge when the transfer window reopens if his situation does not improve.
Tottenham Hotspur claimed a first victory at Chelsea for 28 years with Dele Alli scoring twice in the second half as they came back to win 3-1 and cement fourth place in the Premier League on Sunday.
Liverpool continued their perfect start to the season to stay top of the Premier League after a goal in each half gave them a 2-1 victory over Tottenham Hotspur at Wembley on Saturday.
After picking the ball out of his net several times in a 4-0 drubbing at Southampton two days earlier, Arsenal goalkeeper Petr Cech celebrated a record on Monday by keeping his 170th Premier League clean sheet.
Manchester City take on Chelsea and champions Manchester United meet West Ham United in the key fixtures of Saturday's programme in the English Premier League.
Seasonal cheer has been scarce for Louis van Gaal after a six-match winless sequence for his Manchester United side intensified rumours that he will be sacked and Stoke City are unlikely to be offering any solace on Saturday.
Romelu Lukaku struck twice as Manchester United returned to winning ways after two successive Premier League losses with a 2-0 victory over Burnley at Turf Moor on Sunday.
Champions Manchester City will expect to get back to winning ways at home to Newcastle United in a match which pits Pep Guardiola against his fellow Spaniard Rafa Benitez.
Chelsea replaced Liverpool at the top of the English Premier League with a 1-0 victory at Middlesbrough.
IMAGES from the English Premier League matches played on Saturday
Liverpool take on Manchester United on Sunday, October 25, at 1930.
Chelsea kept up their 100 percent start to the English Premier League season by snatching a 2-1 win at a stubborn Newcastle United on Sunday, grabbing victory thanks to a late own goal by DeAndre Yedlin.
Jamie Vardy wrote a new chapter in his fairytale rise from the wilderness of non-League football to playing for England, when he became the first player to score in 11 consecutive Premier League matches on Saturday.
Champions Manchester United take on cross-town rivals Manchester City in a highly anticipated encounter on Sunday.
The north London outfit were brushed aside by a dominant City side in last Sunday's League Cup final with Pep Guardiola's team converting all three of their shots on target to win 3-0 while Arsenal failed to convert either of their chances.
Romelu Lukaku's 50th league goal for Everton put them on the way to a deserved 2-0 victory over West Ham United on Sunday, ending a run of four league games without a win. It kept the Merseysiders sixth in the Premier League and West Ham in the bottom five.
Chelsea take on Hull City in the opening match of the English Premier League on Saturday, August 15, at 1715 IST.
Chelsea kept up their pursuit of the Premier League's top three clubs with a 1-0 win away to London rivals Crystal Palace on Sunday, thanks to a strike by N'Golo Kante early in the second half.
Tottenham Hotspur routed Bournemouth 5-0 as they leapfrogged City into second place in the league, six points behind leaders Liverpool who thrashed Newcastle United 4-0.
Leicester City manager Claudio Ranieri has asked for a change in mentality to revive the club's Premier League campaign which is in stark contrast to their impressive Champions League form.
City have 89 points, one more than rivals Liverpool, with both teams having three games to play -- and none of them against top six opponents.
'I liked my teams' attitude -- I saw a brilliant attitude -- I saw boys who were fighting with all they have'.
Sergio Aguero and Kevin De Bruyne put on an attacking masterclass to help City rout Leicester City 5-1.
Manchester City suffered their first home Premier League loss in eight months as a shock 3-2 defeat by Crystal Palace on Saturday left Pep Guardiola's champions trailing leaders Liverpool by four points.
Daryl Janmaat, Gerard Deulofeu and Roberto Pereyra all scored late on in response to Eden Hazard dragging Chelsea back into the game with a curler in the 82nd minute after Tiemoue Bakayoko was sent off for a second booking on the half-hour.
Cardiff had lost six of their previous seven games but, knowing that anything but a victory would probably end their survival hopes after one season in the top flight, overcame a strong Brighton start to play with growing confidence and fully deserved their victory.
Champions Manchester City have won their last 10 home league matches scoring a total of 36 goals.
I don't think we can do a Leicester. I am realistic, says Everton manager
Southampton were left in the Premier League's bottom three after losing an early lead to draw 1-1 at home to fifth-placed Tottenham Hotspur on Sunday.