But for third-placed Spurs, who trail leaders Manchester City and Liverpool by five points, this may prove to be a loss that leaves them with too much ground to make up.
Manchester City withdrew from the battle to secure the services of Arsenal's Chilean forward Alexis Sanchez, leaving Jose Mourinho's Manchester United as the most likely destination for the 29-year-old.
Southampton's Senegal forward Sadio Mane scored the fastest Premier League hat-trick as he broke a 20-year-old record to help them lead 5-1 at home to Aston Villa by halftime on Saturday.
Chelsea striker Diego Costa says he was wrong to throw his bib towards manager Jose Mourinho when he was left on the bench during the goalless English Premier League draw with Tottenham Hotspur last month.
Manchester United will travel to third-tier MK Dons in the Capital One Cup second round following the draw on Wednesday, the first time they have been involved at this stage of the competition for 19 years.
Seasonal cheer has been scarce for Louis van Gaal after a six-match winless sequence for his Manchester United side intensified rumours that he will be sacked and Stoke City are unlikely to be offering any solace on Saturday.
Aston Villa have sacked manager Tim Sherwood, the Premier League club announced on Sunday.
IMAGES from the EPL match played between Chelsea and West Brom at Stamford Bridge in London on Monday
A mix of interesting events, coupled with big, shocking results, in the sporting world, grabbed headlines last week. From Manchester United being stunned by Watford to lose their third consecutive match to Nico Rosberg taking the World Championship lead from Mercedes teammate and rival Lewis Hamilton by clinching the Singapore Grand Prix. The Rio 2016 Paralympic Games were brought to a close inside a packed Maracana Stadium on Sunday evening. Not before, we witnessed some enthralling action.
News of all that's transpired on and off the football field
Images from the League Cup matches played on Tuesday
News of all that's transpired on and off the football field
Leicester City's win over Newcastle on Monday not only sent them five points clear of Tottenham Hotspur at the top of the Premier League, it effectively ended the challenge of Manchester City and Arsenal.
Wayne Rooney made history by equalling Bobby Charlton's Manchester United record and becoming the club's leading all-time goalscorer after netting his 249th goal (543 matches) during an FA Cup match against Reading on Saturday.
Premier League newcomers Watford suffered a League Cup upset in a 1-0 loss at Preston North End while five-times champions Aston Villa overcame plucky Notts County 5-3 after extra-time to reach the third round on Tuesday.
Zlatan Ibrahimovic is playing a pivotal role in creating a friendly atmosphere in the Manchester United dressing room, manager Jose Mourinho has said, adding that the striker should not restrict his role in the squad to goalscorer.
Manchester City opened up a two-point lead over their neighbours Manchester United at the top of the English Premier League on Saturday thanks to another display of scintillating brilliance in a 7-2 thrashing of Stoke City at the Etihad Stadium.
Confidence Uwazuruike came to Mumbai a few weeks ago to cover the Great Indian Election Tamasha. On this wishlist was to see Priyanka in flesh and blood. His wish came true this week, but not quite in the way he wanted it to be.
'We can work and fight for it' 'Yes, they had much more of the ball. Yes, they had that apparent control of the game but the biggest save is the double save of their goalkeeper and the biggest decision of the game is the unlucky decision of Michael (Oliver)'
Knee injuries have sidelined him for large parts of this season, however, and the Belgium international has started only four Premier League games.
Manchester City's Kompany out of Liverpool clash with calf injury
News of all that's transpired on and off the football field
Triple European champions Manchester United and their under-fire coach Louis van Gaal face a tricky task against little-known Midtjylland in the last 32 of the Europa League following Monday's draw.
Manchester City coach Pep Guardiola praised Sergio Aguero's natural goalscoring ability after his hat-trick on Wednesday helped defeat Borussia Moenchengladbach 4-0 in their opening Champions League Group C match at the Etihad Stadium.
A summary of Tuesday's League Cup matches.
'We lost two games but these two games were totally different. Against Crystal Palace we didn't deserve to lose. Today we deserved to lose the game'
Mourinho's tinkerings meant a first start of the season for midfielder Scott McTominay, playing on the right of a three-man defence, while Anthony Martial played instead of the dropped Alexis Sanchez. On this evidence, more changes may be needed when United take on Valencia in the Champions League on Tuesday.
Goals rained in for Manchester City and Manchester United but Juergen Klopp's first game in charge of Liverpool was solid rather than spectacular with his new side drawing 0-0 at Tottenham Hotspur in the Premier League on Saturday.
Goals rained in for Manchester City and Manchester United but Juergen Klopp's first game as Liverpool manager was solid rather than spectacular as they drew 0-0 at Tottenham Hotspur in the Premier League.
Images from the English Premier League matches played on Saturday
Leaders Manchester City kept up their unbeaten run with a 3-1 win over Bournemouth on Saturday. Manchester United salvaged a 2-2 draw at Southampton, who sacked manager Mark Hughes on Monday.
A match by match look at this weekend's English Premier League fixtures.
However, experienced goalkeeper Joe Hart and Arsenal midfielder Jack Wilshere were both omitted from a squad announced on Wednesday via a social media video featuring young recreational players from around the country shouting out the names.
If Claudio Ranieri was hoping there might be a player lurking in his reserves to salvage Leicester City's unravelling season he was left disappointed on Saturday as his side were beaten 1-0 by third-tier Millwall in the FA Cup fifth round.
Records fell on the final day of the Premier League season on Sunday as Manchester City beat Southampton 1-0 to become the first team to reach 100 points and Mohamed Salah established a new Premier League goalscoring mark as Liverpool clinched a top-four spot.
News of all that's transpired on and off the football field
News of all that transpired on and off the football field on Friday
Jose Mourinho will select a strong Chelsea side out of respect to high-flying Championship team Derby County when they meet in the quarter-finals of the Capital One Cup on Tuesday.
Leicester City have returned to the Premier League for the first time since 2004 despite not kicking a ball on Saturday after Queens Park Rangers and Derby County both lost.
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