Borussia Dortmund and Feyenoord, who contested the 2002 final, were dumped by French club Sochaux and Czech outsiders Teplice respectively.
Second-half strikes by Federico Valverde, Brahim Diaz and Endrick gave feeble Real Madrid an unconvincing 3-0 win over lowly Real Valladolid.
Manchester City will return to action in the UEFA Champions League on Wednesday against RB Leipzig at the Etihad Stadium.
Chelsea's Petr Cech was named the best goalkeeper from last season's tournament.
Werder Bremen goalkeeper Tim Wiese saved two first-half penalties as the Bundesliga side began their UEFA Cup campaign with a 3-0 win over Braga.
While the tournament saw the emergence of young stars, the usual suspects, the big names flattered to deceive.
UEFA demand that FIFA presidential election be postponed
Struggling Bolton Wanderers held European soccer aristocrats Bayern Munich to a 2-2 draw in UEFA Cup Group F on Thursday.
Dani Carvajal scored a stunning late goal as Champions League winners Real Madrid beat Europa League holders Sevilla 3-2 after extra-time in a UEFA Super Cup thriller in Trondheim, Norway on Tuesday.
This is Real Madrid's third consecutive Champions League title.
A Derlei Silva goal five minutes from the end of extra time secured a 3-2 victory over Celtic.
The Russian national football team has been handed a suspended disqualification from Euro 2016 and a 150,000-euro ($168,300.00) fine after their fans were involved in violent clashes in Marseille, the governing body UEFA said on Tuesday.
European soccer body UEFA will hold a "moment of applause" before the Poland v Portugal Euro 2016 quarter-finals on Thursday in memory of victims of the gun and bomb attack at Istanbul's main airport this week.
Atalanta beat Bayer Leverkusen 3-0 in the Europa League final
UEFA president Michel Platini has repeated his call for the "triple punishment" of red card, penalty and suspension to be dropped following two controversial dismissals in the Champions League this week.
Gennaro Gattuso faces the prospect of disciplinary action for his headbutt on Tottenham Hotspur assistant coach Joe Jordan after UEFA said on Wednesday it was opening a case against the AC Milan captain.
Ukraine champions Shakhtar Donetsk dented Sevilla's bandwagon as the UEFA Cup holders wobbled before securing a 2-2 draw.
UEFA fined AS Roma and warned their forward Adem Ljajic on Wednesday following incidents during last week's Europa League last-32 game against Feyenoord.
Arsenal striker Eduardo da Silva has been handed a two-match ban for deceiving the referee in last week's Champions League play-off against Arsenal, UEFA said on Tuesday.
Zenit St Petersburg and Middlesbrough dented the UEFA Cup hopes of Olympique Marseille and tournament favourites AS Roma.
Players who make racist remarks face a five-match ban while those found guilty of diving will miss at least two games.
Manchester United have asked UEFA to overturn the controversial red card that will keep midfielder Darren Fletcher out of the Champions League final, British newspapers reported on Friday.
Ronaldo admitted that both of them changed the history of football and urged his fans to not hate on Messi.
Middlesbrough beat Basel 4-1, putting them through 4-3 on aggregate and into a meeting with Steaua Bucharest.
Premier League leaders Chelsea have responded to what they describe as an "unprecedented attack" by Europe's governing body UEFA.
Hamburg led a trio of former European champions into the UEFA Cup knockout phase on Thursday and previous winners Valencia also secured a last 32 place. Aston Villa and Ajax Amsterdam progressed from Group F along with Hamburg, whose 2-0 victory at Slavia Prague meant Villa qualified despite a 2-1 home defeat by Slovakia's Zilina.
Middlesbrough beat AS Roma to reach the UEFA Cup quarterfinals for the first time
European football's governing body UEFA is reportedly seeking an internal inquiry on why UEFA guidelines on dealing with racism in football were not followed during Wednesday''s Champions League game between ManchesterCity and CSKA Moscow.
A 29-year old man died on Tuesday after being seriously injured in violent clashes between fans of the AEK Athens and Dinamo Zagreb soccer clubs before a scheduled match in Athens.
UEFA opens investigation into Barca payments to ex-refereeing official
Former England centre-back Sol Campbell says European football's governing body UEFA should introduce points deductions as a deterrent to stop racism rather than fining national associations when it happens.
Sweden missed out on the finals for the first time in 28 years on a night in which their fixture with Belgium was abandoned
Several players across the continent are poised to make a name for themselves on the international stage.
They were charged for the improper conduct of one of their supporters during their 2-0 defeat by hosts Portugal.
IMAGES from the UEFA Champions League matches played on Wednesday
UEFA's executive committee will discuss the precise definition of own goals on Friday in an issue of huge importance to Europe's top strikers and defenders. European soccer's governing body is keen to end confusion over whether a goal should be credited to an attacking player, even when it has been diverted into the net by a member of the defending team.