Arsenal's victory was scrappy and nervy but Laurent Koscielny's 72nd-minute winner was enough to move them two points clear at the summit after LeicesterCity's surprise push faltered with a goalless draw at home to 10-man Bournemouth.
Luis Suarez marked his return to Premier League action with two goals to help Liverpool to a 3-1 win at managerless Sunderland that lifted them to second in the table on Sunday.
Stevan Jovetic and Jesus Navas scored their first goals for ManchesterCity who avenged last season's shock FA Cup final defeat by Wigan Athletic with a 5-0 victory in the League Cup third round on Tuesday.
Barcelona's rampant trio of Neymar, Luis Suarez and Lionel Messi all found the net at the weekend and unsung Leicester City found themselves in the record books when their England striker Jamie Vardy scored for the 11th straight game.
Arsenal fear Sanchez injury loss could be 'big blow'.
News of Van Gaal's impending departure from the club leaked out minutes after Saturday's 2-1 extra-time victory over Palace and, following relentless media speculation and a day of negotiations, it was confirmed by both sides on Monday evening.
In April last year Leicester City were seven points adrift at the foot of the Premier League and seemingly going down.
Chelsea's slim hopes of winning the Premier League all but evaporated in the Stamford Bridge sunshine on Sunday as Norwich City ground out a 0-0 draw that left them hanging on to top- flight status by their fingernails.
First-half goals by Danny Welbeck and Alex Iwobi earned Arsenal a first win in four league games to revive their Premier League title hopes in the early kickoff at Goodison Park on Saturday.
Anthony Martial introduced himself to Manchester United fans with a superb goal to complete a 3-1 win over bitter rivals Liverpool and cap a much-improved performance from Louis van Gaal's side on Saturday.
Liverpool took a giant step towards their first title in 24 years with a 3-2 win at a plucky Norwich City on Sunday, opening up a five point lead over second-placed Chelsea with three matches remaining.
An Eden Hazard hat-trick swept Chelsea back to the top of the Premier League on Saturday when they beat Newcastle United 3-0 at Stamford Bridge after previous leaders Arsenal were thrashed 5-1 at Liverpool.
IMAGES from the English Premier League matches played on Saturday
Tottenham Hotspur fluffed their last-day lines with a 5-1 defeat at relegated, 10-man Newcastle United that left them third in the Premier League behind bitter north London rivals Arsenal.
In England, the celebrations went on at Leicester City as they marked their fairytale Premier League success with another win while champions Juventus' long unbeaten streak in Italy came to an end.
News of all that's transpired on and off the football field
'Keep Calm And Carry On' could be Claudio Ranieri's motto for the second half of the season after Leicester City earned a 1-0 win at Tottenham Hotspur on Wednesday to put the heat back on Premier League leaders Arsenal.
News of all that's transpired on and off the football field
Charlie Adam scored twice as Stoke City beat Manchester United 2-1 on Saturday to show the flailing Premier League champions it will take more than one big-money signing to improve their fortunes.
Arsenal maintained their challenge for a first trophy in nine seasons when they beat Liverpool 2-0 at the Emirates Stadium to open up a five-point lead at the top of the Premier League on Saturday.
Jose Mourinho got the better of old adversary Arsene Wenger once again as Chelsea showed their strength-in-depth by reaching the League Cup quarter-finals with a 2-0 win over London rivals Arsenal on Tuesday.
Chelsea's title ambitions suffered a major blow with a shock 2-1 home defeat by bottom side Sunderland on Saturday, handing the initiative to English Premier League leaders Liverpool who visit lowly Norwich City on Sunday.
Barcelona must to wait to confirm a place in the Champions League last 16 after dropping points for the first time in Group D in an absorbing 0-0 draw at Olympiakos Piraeus on Tuesday.
Manchester United ushered in a new era under interim manager Ryan Giggs with a 4-0 Premier League win over Norwich City on Saturday full of the verve and attacking intent often absent under the sacked David Moyes.
Arsenal beat Fulham 2-0 at the Emirates and Manchester City beat Cardiff City 4-2 at the Etihad before Liverpool could only manage a 2-2 draw at Anfield having trailed 2-0.
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Swiss qualifier Timea Bacsinszky continued to swipe past the seeds at the Wuhan Open on Wednesday by dumping World No 4 Maria Sharapova from the hard court tournament with a 7-6(3), 7-5 victory.
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