Federer decided to end his Roland Garros campaign on Sunday, a day after winning a gruelling third-round match against Dominik Koepfer.
The fifth seeded German did not let up and another break confirmed the win in two hours and 40 minutes.
Images from Day 5 of the 2021 French Open, in Paris, on Thursday.
The world No 1 said he will play the French Open and Wimbledon without a coach after splitting with Tony Roche.
Tsitsipas pulled out of the Wimbledon warm-up event in Halle, Germany, because of personal reasons
Krejcikova became the first player to win both the women's singles and doubles title in Paris since Mary Pierce completed the feat in 2000.
World number two Simona Halep tested positive for the novel coronavirus and is recovering well from her mild symptoms.
Djokovic will be nowhere near the centre court after losing his bid to overturn a second visa cancellation.
World number one Novak Djokovic said his win over Rafa Nadal in Friday's epic French Open semi-final was one of the top three matches he had played and he would remember it forever.
Persistent drizzle and a chill wind sweeping the almost-empty Roland Garros grounds.
Monfils said all players were not similarly equipped to deal with the pressure of being a top athlete.
Verdasco questions French Open COVID-19 testing protocols after withdrawal
Ash Barty ended Australia's 44-year wait for a home winner at the Australian Open when the world number one staved off a fightback from American Danielle Collins to complete a 6-3, 7-6(2) win.
Barty's athleticism is remarkable.
Shapovalov pulls out of French Open.
The 6-foot-5 frame of Matteo Berrettini will be standing in the way of Novak Djokovic's relentless pursuit of hoarding as many tennis milestones as possible when the two meet in a Wimbledon final where both men will be eyeing the record books.
Defending champion Simona Halep pulled out of Wimbledon on Friday after failing to recover from a calf injury she suffered last month, the world number three Romanian said.
French Open champion Rafael Nadal has said he nearly ended his season after being forced to withdraw from the Indian Wells semi-finals with a knee injury in March.
Australian Nick Kyrgios produced another extraordinary performance to demolish compatriot Alex de Minaur 6-2, 6-3 at the Canadian Masters on Thursday, a day after stunning world number one Daniil Medvedev.
Images from Monday's action at the French Open.
IMAGES from Day 7 of the French Open, at Roland Garros, on Saturday.
The two great rivals meet at Roland Garros for the first time in eight years in Friday's tie.
Barbora Krejcikova claimed her maiden Grand Slam title when she beat Russian Anastasia Pavlyuchenkova
Images from Day 10 of the 2020 French Open, at Roland Garros, in Paris.
It was unclear exactly what happened to world number 76 Musetti whose stylish game was threatening to send Djokovic to his earliest Roland Garros exit since 2009.
Djokovic said he was '50-50' about competing at the Tokyo Olympics
Images from Day 10 of the 2021 French Open at Roland Garros in Paris on Tuesday.
Images from Day 9 of the Wimbledon 2022 Championships at the All England Lawn Tennis and Croquet Club in London, on Tuesday.
Rafael Nadal is hunting a record-extending and almost unbelievable 12th Roland Garros title is remarkable in itself.
Images from the 2022 Wimbledon Championships at the All England Club in London on Sunday.
Monfils was playing in his first match in nearly seven months after the season resumed following the COVID-19 hiatus.
Images from Day 10 of the 2022 Australian Open in Melbourne on Wednesday.
'Neither I nor members of my team have symptoms of coronavirus. We carry out tests regularly. We will quarantine ourselves in accordance with current procedures'
Rafael Nadal is tied with Roger Federer as the player with the most men's singles majors and the Spaniard can now overtake his great rival who has skipped the Australian Open.
Most of the estimated 70 million euros net earnings from the claycourt Grand Slam tournament are spent on helping French tennis.
Djokovic did not play badly in the final but it took him 55 minutes before he registered his first game in what turned out to be a mauling.
Yet the warrior-like instincts kicked in and we were all reminded that Nadal, as long as he is standing, remains a physical and psychological force of nature on a tennis court.
Jamie Murray criticises French Open doubles prize money cut, hotel conditions.
The 2011 US Open champion could not wait to join her friend for the 'Barty Party'.
Nadal plays Berrettini in one semifinal, knowing he's potentially two match wins from a 21st major title.
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