Japan's Nishikori was the first man representing an Asian country to break through to a Grand Slam final at the 2014 tournament before Marin Cilic stopped him in the title match.
Look who we spotted at the Flushing Meadows this year.
Serena Williams returns to the Arthur Ashe Stadium on Sunday
Factbox on Rafael Nadal, who beat Novak Djokovic 6-0, 6-2, 7-5 on Sunday to win a record-extending 13th French Open title:
The first leg of Djokovic's Adria Tour is being held at his tennis complex by the Danube River, with Germany's Alexander Zverev, Austrian Dominic Thiem and Bulgarian Grigor Dimitrov arriving for the event.
Second seed Roger Federer powered to a 6-4, 6-3, 6-2 win over Roberto Bautista on Tuesday, charging into the quarter-finals of the US Open for the 10th time in 11 years.
Only one player has beaten Rafael Nadal on his beloved claycourts this year and that man, Austria's Dominic Thiem, blocks the Spaniard's path to the French Open final.
Images from Sunday's action at the Australian Open.
Muguruza seals semi-final berth, Pliskova beats Krejcikova at WTA Finals.
Garbine Muguruza was relieved to finally avoid tripping at the last hurdle and end her trophy drought
List of French Open men's singles champions:
Eighteen time Grand Slam champion Roger Federer has climbed up to the fourth spot in the latest ATP rankings after lifting his third Miami Open title by beating long-time rival Rafael Nadal.
The latest tennis rankings have been announced by the ATP and WTA
Rafael Nadal will skip the Miami Open that begins later this month in a bid to recover from a back injury in time for the clay court swing
Images from Day 6 of the French Open matches played at Roland Garros in Paris on Friday.
Ramkumar became the first Indian in seven years to advance to the singles final of an ATP World Tour event but missed out on ending India's 20-year title drought when he lost the Hall of Fame final to Steven Johnson on Sunday night.
The fifth-seeded Austrian, who saved two match points, will face Novak Djokovic on Saturday after the world number one's opponent Marin Cilic withdrew with food poisoning.
With 1,500 points available for an undefeated champion next week, the tournament could produce a thrilling climax with Murray and Djokovic, who have never met at the O2, facing off in the final for the year-end number one ranking.
Top seed Simona Halep came back from a set down for the third time in the tournament to beat Kazakhstan's rising star Elena Rybakina 3-6, 6-3, 7-6(5) to win the Dubai Duty Free Tennis Championships for the second time on Saturday. In a battle that lasted nearly two-and-a-half hours, the match came down to a tiebreak where two shots that went agonisingly wide for Rybakina eventually decided the title in front of a noisy crowd that constantly chanted Halep's name.
World number one Rafael Nadal made light work of Greek teenager Stefanos Tsitsipas to win the Barcelona Open final 6-2, 6-1 on Sunday, lifting the trophy for a record-extending 11th time.
No complaints but quarantine differentials were a mistake: Zverev
Third seed Rafael Nadal remains on course for a 10th Barcelona Open title, advancing to the quarter finals with a routine 6-3, 6-4 victory over Kevin Anderson.
World No 1s Andy Murray and Angelique Kerber have been named top seeds for the first major of the season, Australian Open, which will commences on January 16.
Andy Murray recovered from an early setback to beat Austrian Dominic Thiem.
'Last year I was one point away to the final. I felt competitive last couple of years, so why do I need to change that?'
Italy's Fabio Fognini said it was a 'strange feeling' playing a Davis Cup tie with no fans. Japan were also playing their tie against Ecuador in an empty stadium in Miki because of the coronavirus spread, which has played havoc with sporting fixtures across the world.
Men's governing body ATP on Monday unveiled a revised system for calculating world rankings when the season resumes in August following a five-month suspension due to the COVID-19 pandemic. Traditionally the ATP rankings operates on a formula of 18 best results over 52 weeks but will now cover a 22-month period from March 2019 through December 2020.
India's leading players Prajnesh Gunneswaran and Sumit Nagal lost in the pre-quarter-finals, ending India's challenge in the men's singles, of the Bengaluru Open, in Bengaluru, on Thursday.
'Irresponsible' Djokovic panned for Adria Tour misadventure.
World number three Roger Federer is playing his first tournament on clay for three years as he prepares for the French Open.
Wimbledon finalists Novak Djokovic and Roger Federer are on a semi-final collision course at the US Open after they were placed in the same half of the draw.
Greek tyro Stefanos Tsitsipas' dream run at the Rogers Cup continued on Friday as the teenager toppled defending champion Alexander Zverev 3-6, 7-6(11), 6-4 to reach the semi-finals in Toronto.
Nadal meets the 'new Nick' Kyrgios in fourth-round blockbuster
A very different Australian Open comes to a familiar end on Sunday as Novak Djokovic looks to thwart another challenge to his Melbourne Park dynasty from the latest Grand Slam aspirant in Daniil Medvedev.
hampion Rafael Nadal and top-ranked Novak Djokovic turned in impressive displays to reach the Monte Carlo Masters quarter-finals on Thursday. Nadal, chasing a record-extending 12th Monte Carlo title, broke Grigor Dimitrov's serve on four occasions to defeat the Bulgarian 6-4 6-1.
Kenin, Andreescu to be part of team event in Charleston in June
Roger Federer's bid to win a ninth Halle Open title was ended in the semi-final on Saturday by teenage German Alexander Zverev, who defeated the 17-time Grand Slam champion 7-6(4), 5-7, 6-3.
The 'Big Three' of tennis world -- Roger Federer, Rafael Nadal and Novak Djokovic -- won't lose much due to the suspension of professional tours since they have already created their own legacies but the real struggle is for lower-ranked players, including the Indians, says legendary Vijay Amritraj. Amritraj said the trio of Federer, Djokovic and Nadal, who have a tight grip over Grand Slam tournaments, won't feel any financial stress or the pressure of progress.
The 21-year-old has now recorded victories over all of tennis's so called 'Big Three' this year, having beaten Roger Federer at the Australian Open and Rafa Nadal in Madrid.