United beat Leicester City at Old Trafford in the opening game of the season but Spurs present a very different quality of opponent.
Croatia ruthlessly exposed England's limitations in the second half of the World Cup semi-final on Wednesday as Zlatko Dalic's side fought back to secure a famous 2-1 extra-time victory.
England, appearing in their first semi-final since 1990, had looked on course for their first final since 1966 as they led through Kieran Trippier's fifth-minute free kick and totally dominated the opening half.
England forward Jamie Vardy is "looking doubtful" for the World Cup quarter-final against Sweden on Saturday after suffering a groin strain having come on as a late substitute in the last-16 win over Colombia, manager Gareth Southgate has said.
Spurs beat Ajax 3-2 in the second leg of the semi-final on Wednesday and will face Liverpool on June 1 in Madrid.
England defender Chris Smalling headed the only goal with five minutes left as they beat 10-man Portugal 1-0 in a turgid Euro 2016 warm-up match at Wembley in London, on Thursday.
Strikers Marcus Rashford and Daniel Sturridge made Roy Hodgson's final 23-man England squad for Euro 2016 on Tuesday but winger Andros Townsend and midfielders Danny Drinkwater and Fabian Delph were left out. England are taking five forwards to the 24-team tournament in France, which starts on June 10, with Sturridge selected despite doubts over a calf problem. The injury had forced the Liverpool striker to miss England's last two friendly matches, including Friday's win over Australia in Sunderland. The 18-year-old Rashford, who signed a new long-term deal with Manchester United on Monday, became the youngest player to score on his England debut in the 2-1 win at the Stadium of Light. He scored that goal 138 seconds into what was only his 19th professional match, marking him out as one of the brightest emerging prospects and winning plaudits from Hodgson.
Uruguay will head to the World Cup on a winning note after beating Uzbekistan 3-0 in a chilly warmup in front of their own fans on Thursday.
The first few months of this season have been disappointing, as Spurs have won only three of their opening 12 Premier League games and are in 14th spot. They were also thrashed 7-2 by Bayern Munich in the Champions League and knocked out of the League Cup by fourth-tier Colchester United.
Rediff.com has this and a whole lot more exciting action from the week gone by, encapsulated in this photo feature.
Germany's Lukas Podolski capped his international swansong with a sensational goal to give the world champions a 1-0 victory over England in a friendly on Wednesday.
The London club dominated the first half but fell behind to a superb goal from their former winger Aaron Lennon before young midfielder Dele Alli furthered his case for a place in England's midfield with a classy equaliser just before the break.
Here are five talking points from the weekend's Premier League action:
Chelsea's David Luiz never really looked cut out for a role as a defensive rock in one of England's meanest rearguards.
England's Harry Kane and Jamie Vardy struck in a 2-1 friendly win over fellow Euro 2016 finalists Turkey on Sunday as the home side warmed up with a performance that highlighted their potency in attack and defensive limitations.
'Tottenham's teamwork which has given them a chance of reeling in Leicester.'
Images from EPL matches played on Tuesday
It is a mark of how far Tottenham Hotspur have come that they start as favourites to win what could be a pivotal Champions League Group E fixture away to Bayer Leverkusen on Tuesday despite the absence of key defender Toby Alderweireld.
News of all that transpired on and off the football field.
Spanish teams have ruled with an iron fist in Europe for the last few years but a disappointing round of results in the Champions League has left the media wondering if this dominant era might be grinding to a halt.
For all the positives that England can take from their performance against Russia in their opening Euro 2016 game there remains the worrying issue that their sophisticated modern defenders remain vulnerable to the most basic of attacking ploys -- a long punt into the box.
Premier League champions Chelsea eased past a disappointing Everton with goals from Spaniards Cesc Fabregas and Alvaro Morata sealing a 2-0 victory on Sunday.
When England fans sang about '30 years of hurt' at Euro '96 they had high hopes of ending the pain with a first trophy since the 1966 World Cup but 20 years on from that agonising near miss there is precious little optimism in the air.
Juergen Klopp's reign as Liverpool manager began with a few points made but only one gained from an exciting, end-to-end 0-0 draw against Tottenham Hotspur at White Hart Lane on Saturday.
Giorgio Chiellini's assertion that Tottenham Hotspur 'always miss something to arrive at the end' would have chiselled deep into a nerve for fans of the north London club.
Southgate's formation and tactics have been hailed as progressive and modern, there is also something traditionally English about the team's strengths.
England's 2-1 defeat by Iceland at Euro 2016 may have looked like one of the worst reverses in their history yet in many was it was a perfectly logical result.
Late goals from Eden Hazard and Nemanja Matric sealed a 4-2 victory for Chelsea over London rivals Tottenham Hotspur in a rip-roaring FA Cup semi-final at Wembley on Saturday.
Iceland have already exceeded expectations by qualifying second in their group behind Hungary and will go into the game with nothing to lose and the whole world, beyond England, willing them on.
A rejuvenated Manchester United claimed a sixth win from six matches since former striker Ole Gunnar Solskjaer stepped in following the sacking of Jose Mourinho.
Images from Sunday night's English Premier League matches.
Harry Kane was hailed as 'unbelievable' after the England striker's 21st and 22nd goals of the season inspired Tottenham Hotspur to a routine win at hapless Aston Villa on Sunday that boosted their Premier League title ambitions.
Rediff.com brings a preview of the main matches coming up this weekend in the English Premier League.
IMAGES from Saturday's English Premier League matches.
Chelsea brought a whole new dimension to the Premier League title race when they handed Manchester City their first defeat of the season on Saturday to leave Mohamed Salah-inspired Liverpool as the new leaders.
Spain coach Luis Enrique said football had been unfair to his side after Thursday's dramatic 3-2 defeat in Croatia left them in danger of failing to reach the UEFA Nations League finals.
Liverpool substitute Adam Lallana struck deep into stoppage time to snatch a 5-4 win over shell-shocked Norwich City in an extraordinary Premier League game at Carrow Road on Saturday.
England's World Cup 2018 team, and remarkable similarities emerge between the XI expected to start the semi-final against Croatia
Tottenham Hotspur's Harry Kane pounced on a piece of comical defending to secure a 1-0 win over Sunderland in the Premier League on Sunday although he was later wheeled away on a stretcher after suffering an ankle injury.
Arsenal's Olivier Giroud produced a piece of New Year's Day magic to keep Arsenal in sight of Premier League leaders Chelsea while Harry Kane's double bolstered Tottenham Hotspur's ambitions as London's triple assault on the title continues.