Greece's Tsitsipas battled back from 3-5 down in the third set to eliminate Medvedev with a 6-3, 6-7(11), 7-6(1) win to set up a showdown on Friday with Rublev for the Red Group's other semi-final spot.
Second seed Daniil Medvedev will launch his bid to win his first major title against veteran Frenchman Richard Gasquet.
Carlos Alcaraz moved to within two wins of completing the 'Sunshine Double'
The win put Nadal one clear of Federer and world number one Djokovic on the all-time Grand Slam titles race.
Wimbledon's decision to ban Russian and Belarusian players from this year's tournament following the invasion of Ukraine was wrong and lacked respect, world number one Novak Djokovic said on Monday.
Djokovic had been favourite to win a 10th title at Melbourne Park and claim a 21st Grand Slam crown but the Serb now faces being deported from Australia.
Osaka takes equity stake in crypto exchange FTX
Madison Keys swept past Wimbledon champion Elena Rybakina 6-2, 6-4 at the Cincinnati Open on Friday, setting up a semi-final clash with Petra Kvitova after the Czech defeated Ajla Tomljanovic.
US Open champion Carlos Alcaraz has become the youngest world number one since the ATP rankings began in 1973.
Novak Djokovic eased into the last four with a commanding performance over Japan's Kei Nishikori but world number two Daniil Medvedev bowed out of the men's singles at the Tokyo Olympics.
Tennis matches at the Ariake Tennis Park will begin from 3pm local time (0600 GMT) from Thursday, governing body International Tennis Federation said after requests from players who had struggled in the stifling weather.
The Australian Open men's singles final offers a rematch of the dramatic 2021 French Open final, in which Djokovic came back from two sets down to snatch the title and leave Greek Tsitsipas heartbroken.
Former champions Novak Djokovic, Rafael Nadal and Serena Williams have all entered next month's Western & Southern Open in New York, which will serve as a tune-up for the US Open, tournament organisers said on Wednesday. Organisers of the August 20-28 event, which was relocated from Cincinnati this year because of COVID-19, said defending champions Daniil Medvedev and Madison Keys are also among the initial entries.
India's campaign at the US Open came to an end after Rohan Bopanna lost in the men's and mixed doubles, in New York, on Sunday. India's top-ranked men's doubles player and his Canadian partner Denis Shapovalov lost 3-6, 4-6 to 15th seeds Neal Skupski and Jamie Murray of Great Britain in a second round match that lasted 75 minutes.
Alcaraz outlasts Hurkacz, Ruud stunned at Canadian Open
'I am playing tennis because I love to play tennis'
'To be part of Team Europe together is great and if we're able to possibly share the court one more time as a doubles pairing then this would be a truly special experience for us both at this stage in our careers.'
Rafael Nadal said he was lucky to be part of an era of tennis that included Roger Federer and Novak Djokovic after the Spaniard won a men's record 21st Grand Slam title at the Australian Open to move one ahead of his two great rivals.
However, the 33-year-old Spaniard will not know until later on Friday whether his Herculean effort was in vain.
A round-up of all tennis action on Saturday.
Daniil Medvedev fired Russia into the final of the ATP Cup on Saturday with a tense 3-6, 6-3, 7-5 win over an injury-hampered Alexander Zverev after the German destroyed a racket in frustration over a lost service break.
Djokovic has won the last three editions of Wimbledon in 2018, 2019 and last year
Federer, Nadal and Djokovic had made it near impossible for their peers to live, and thrive, amongst them. But the coming generation, which hasn't been as scarred by defeat at the hands of the Big 3, may make tennis unpredictable again.
Indian Wells organisers said on Tuesday that world number two Novak Djokovic had been placed in the tournament's draw but it was unclear if the Serbian would be permitted to enter the United States.
Medvedev opened as the +225 favorite at BetMGM but has seen his odds lengthen slightly despite the absence of two of his top threats. He has had a rollercoaster 2022 since falling to Nadal in the Australian Open final.
Becomes only third Indian to win a singles match at the Games.
Novak Djokovic enjoyed a stress-free return to US competition following a two year absence
Italian 10th seed Jannik Sinner stunned world number one Carlos Alcaraz 6-7(4), 6-4, 6-2 in an epic Miami Open semi-final duel on Friday, as Petra Kvitova set up a meeting with Elena Rybakina in the women's championship match.
Images from the men's singles fourth round matches at the Australian Open, on Sunday.
Russia's Daniil Medvedev defeated Benoit Paire of France 6-3, 6-4 in the first round of the Abierto Mexicano tournament in Acapulco on Tuesday to get his quest for the world number one ranking off to a winning start.
A round-up of all the tennis action from around the globe.
Swiss great Roger Federer said he has faced no setbacks and is recovering well after his latest knee operation.
Djokovic missed the Australian Open after being deported for not having been vaccinated against COVID-19 and will not be allowed to compete at the US Open
World number one Rafael Nadal has been drawn alongside defending champion Alexander Zverev, Association of Tennis Professionals (ATP) reported.
Pole says she feels much better prepared to handle the pressure of her latest career milestone.
Muguruza wins all-Spanish clash with Badosa at WTA Finals
World number one Novak Djokovic had to work hard for a three-set victory over Hungarian Marton Fucsovics at the Paris Masters on Tuesday in his first match since losing the U.S. Open final in September.
Images from Day 10 of the 2021 French Open at Roland Garros in Paris on Tuesday.
Images from Day 5 of the 2022 French Open at Roland Garros in Paris on Thursday.
Images from Day 5 of the 2023 Wimbledon Championships on Friday.