The new English season got off to a familiar start as two Sergio Aguero goals, including his 200th for the club, handed Manchester City a 2-0 win over Chelsea and claim the FA Community Shield for the fifth time at a sun-baked Wembley.
The racist chants took the shine off a great day for Chelsea who have tightened their grip on fourth place.
United led through Juan Mata's 11th minute strike but just before halftime the visitors were level when De Gea weakly parried an Antonio Rudiger shot into the path of Marcos Alonso.
Francesco Totti came off the bench to make his 600th league appearance for AS Roma as they beat in-form Chievo 3-0 at home on Sunday to climb to second place in Serie A.
IMAGES from the English Premier League matches played on Saturday.
News of all that's transpired on and off the football field
Chelsea, however, were unlucky after they were again denied by the woodwork.
Chelsea's inability to score a second goal proved costly as Karim Benzema's effort levelled things up
Unlike the Champions League, Premier League referees have so far refused to take a second look at decisions on pitchside monitors
A round-up of Tuesday's action in the UEFA Champions League.
Chelsea manager Frank Lampard was delighted with the discipline of his team, who ended United's 19-game unbeaten run.
IMAGES from the English Premier League matches played on Wednesday.
Real Madrid saw off a stirring Chelsea fightback to book their place in the Champions League semi-finals following a 3-2 defeat after extra time in a scintillating second leg at the Santiago Bernabeu on Tuesday to go through 5-4 on aggregate.
Karim Benzema's hat-trick earned Real Madrid a 3-1 win at reigning European champions Chelsea in their Champions League quarter-final first leg on Wednesday. In another quarter-final match, Villarreal stunned six times European Cup winners Bayern Munich 1-0.
Brighton & Hove Albion scored three times in the second half to fight back from two goals down and beat Manchester City
Chelsea lost their opening Premier League game with Lampard in charge 4-0 to Manchester United on Sunday and face Liverpool in the UEFA Super Cup on Wednesday.
A summary of Sunday's action in the Premier League.
Images from Wednesday's action in the Champions League.
Headed goals from Anthony Martial and captain Harry Maguire earned Manchester United a hard-fought 2-0 win at toothless Chelsea on Monday amid more VAR controversy, putting them back in the hunt for a top-four Premier League finish. The VAR system made the headlines once again after two Chelsea efforts were ruled out and England international Maguire escaped sanction for a kick out at Michy Batshuayi.
Images from the UEFA Champions League matches played on Wednesday.
English Premier League leaders Liverpool opened up a 22-point gap at the top of the table with second-half goals from Alex Oxlade-Chamberlain, Jordan Henderson and a Mohamed Salah brace giving them a 4-0 home win over Southampton. A rare double from defender Antonio Rudiger earned Chelsea a point in an entertaining 2-2 draw with third-placed Leicester City.
Sheffield United's David McGoldrick scored twice as they stunned Chelsea with a 3-0 win at Bramall Lane on Saturday, loosening the visitors' grip on a Premier League top-four place. Raheem Sterling struck a hat-trick as Manchester City crushed Brighton 5-0 at the AmEx Stadium in the Premier League on Saturday.
IMAGES from EPL matches played on Wednesday
The Professional Footballers' Association (PFA) called for a government inquiry into racism in the English game following the match, which Chelsea won 2-0.
Imperious Liverpool extended their Premier League home winning streak against Arsenal to six on Saturday with an easy 4-0 victory that lifted them to second in the table.
Chelsea a 1-0 win over Manchester United in a compelling Premier League clash on Sunday
Antonio Conte's return to Italian football on Tuesday proved such a chastening experience as he watched his Chelsea side dismantled by AS Roma in the Champions League that he worries they could be set for a "very difficult" season.
However, one goal proved enough for City who picked up their sixth successive league win to move four points clear of Liverpool, who host Aston Villa later on Saturday, at the top of the standings.
Images from Sunday's English Premier League matches.
Liverpool started the ball rolling with a convincing 4-1 win at home to promoted Norwich and City responded a day later with an even more emphatic 5-0 victory at West Ham United.
Arsenal fought back from a goal down against old foes Chelsea to reach the League Cup final as Granit Xhaka poked home to complete a 2-1 second-leg win on Wednesday that set up a Wembley showdown with Manchester City.
Chelsea's third successive league win lifted them level on 18 points with Leicester City but are top thanks to a better goal difference. Leicester face Liverpool on Sunday.
Images from the English Premier League matches played on Wednesday
Images from the World Cup qualifying matches played on Wednesday night.
Images from EPL matches played on Saturday.
Spaniard Herrera finished off a fine move with a precise header from Pogba's cross just past the half-hour and United's French midfielder scored himself when he nodded powerfully home from a Marcus Rashford delivery before the break.
The visitors got off to the perfect start when a mix up at the back saw Riyad Mahrez square for Jamie Vardy to tap into an open goal in front of the Kop in the third minute. Liverpool looked for an immediate riposte, but Salah missed two gilt-edged opportunities before Sadio Mane saw an effort disallowed for offside as Juergen Klopp's men grew frustrated.
Included in Barcelona squad to face Dortmund
This and more from the happenings in the world of football
Images from the UEFA Champions League matches played on Tuesday night.