Manchester United spurned a chance to move into the Premier League's top four after striker Zlatan Ibrahimovic missed a penalty in a 1-1 draw against 10-man Bournemouth on Saturday.
Manchester City soared above the fog swirling round the Etihad Stadium to demolish Tottenham Hotspur 4-1 and leave the rest of the Premier League peering into the distance in search of Pep Guardiola's record-breaking team on Saturday.
Chelsea put all their struggles away and looked like a renewed squad, stamping their class over Crystal Palace in their English Premier League match at the Selhurst Park on Sunday.
Images from EPL matches played on Saturday.
Two late goals by Everton substitutes brought the Merseysiders a third successive win when they beat Crystal Palace 2-0 at Goodison Park in Sunday's only Premier League game.
Soccer highlights from across the globe.
Crystal Palace left Manchester City's hopes of retaining their Premier League crown in tatters after a 2-1 win at Selhurst Park on Monday to leave Manuel Pellegrini's side trailing a distant fourth in the title race.
Three of the four managers leading their teams out at Wembley for this weekend's FA Cup semi-finals will do so knowing defeat could have serious ramifications for their short-term future.
Leicester City stumbled on their march towards the Premier League title when they drew 2-2 with West Ham United and had goalscorer Jamie Vardy sent off at the King Power Stadium on Sunday.
Images from the English Premier League matches played on Saturday
Here are five talking points from the weekend's Premier League action:
It was a day of role reversal as Jose Mourinho's often cautious Chelsea thumped Everton 6-3 in a thriller on Saturday while champions Manchester City's attacking talents were blunted in a shock 1-0 home defeat by Stoke City.
Liverpool moved into the Champions League qualifying spots after a 3-0 win at Burnley on Wednesday took them above Leicester City and into fourth place with one round of Premier League matches remaining.
Match-by-match facts and statistics ahead of the Premier League
Danny Welbeck and Jesse Lingard both scored twice as English champions Manchester United got their first win of the David Moyes era with a 5-1 victory over an A-League All Stars team at the Olympic Stadium on Saturday.
In a gripping title race, Liverpool showed they are ready to push Manchester City right until the final seconds of this season with their spirited 3-2 win at Newcastle United.
The Premier League kicked off in unique fashion on Saturday as an own goal by Tottenham Hotspur's Kyle Walker gave Manchester United a 1-0 victory in an undistinguished season opener at Old Trafford.
IMAGES from Premier League matches played on Saturday.
Images from the English Premier League matches on Saturday.
Images from the English Premier League matches played on Saturday
Images from the English Premier League matches played on Sunday.
Imperious Liverpool extended their Premier League home winning streak against Arsenal to six on Saturday with an easy 4-0 victory that lifted them to second in the table.
Liverpool's Egyptian forward Mohamed Salah scored his 29th Premier League goal six minutes from time to secure a 2-1 win at Crystal Palace that took them up to provisional second spot in the table on Saturday.
Sunderland striker Steven Fletcher scored in each half to help his beleaguered side earn a much-needed 3-1 win at Crystal Palace in their Premier League match at Selhurst Park on Monday.
Aston Villa beat Crystal Palace 1-0 to win a Premier League match for the first time since August while a late goal from Paul Dummett earned a 3-3 draw for Newcastle United against Manchester United on Tuesday.
IMAGES from soccer matches played in the EPL, La Liga and Serie A on Tuesday.
Images from the English Premier League matches played on Saturday
Images from the English Premier League matches played on Sunday
Brighton and Hove Albion scored late to earn a 1-1 draw at Crystal Palace. Sheffield United and Fulham also drew 1-1 as both teams picked up their first points.
Philippe Coutinho inspired Liverpool to a comfortable 3-1 home win over Everton in the 228th Merseyside derby on Saturday to move provisionally up to third in the Premier League.
Liverpool put their recent troubles behind them, showing touches of their best early-season vibrancy to overcame Arsenal 3-1 at a jubilant Anfield and leapfrog the Gunners into third place in the Premier League on Saturday.
Manchester United substitute Jesse Lingard's superb volley in extra time secured a 2-1 win over CrystalPalace in the FA Cup final at Wembley Stadium on Saturday for their first major trophy in three years.
Images from the English Premier League matches played on Wednesday.
IMAGES from the English Premier League match played on Saturday
A summary of Saturday's matches in the English Premier League.
Manchester United manager Jose Mourinho has promised to show plenty of restraint and respect if he inflicts a first Premier League defeat of the season on his former side Chelsea on Saturday.
Inter will be his sixth club in a career which began when he made his debut for Anderlecht as a 16-year-old and has taken him to Chelsea, West Bromwich Albion and Everton.
Images from the English Premier League matches played on Saturday
Photos from the Premier League matches played on Sunday
Liverpool made it three wins out of three as Mohamed Salah scored twice in a convincing 3-1 victory over Arsenal on Saturday to take control at the top of the Premier League.