With no fans allowed into venues and Real playing their home games at the 6,000-capacity Alfredo Di Stefano stadium while the Santiago Bernabeu is being refurbished, it will be a title race unlike any other.
Gareth Bale again came to Real Madrid's rescue by heading home the winner in a 1-0 win at Real Sociedad on Saturday that keeps their title hopes alive.
Real Madrid forward Cristiano Ronaldo faces a race against time to be fit for the Champions League semi-final second leg with Manchester City on May 4.
Under-pressure Real Madrid coach Rafa Benitez believes there is a campaign against him and the club and that the team is not playing as badly as is being made out ahead of the La Liga game against Real Sociedad on Wednesday.
Last season's treble winners Barca are in their worst run of form in La Liga since coach Luis Enrique took charge in August 2014.
La Liga leaders Barcelona earned a narrow 1-0 win over Real Valladolid to move seven points clear at the top, while Real Madrid lost 2-1 at home against Girona to fall to third behind Atletico Madrid.
Among other transfer news globally, defender Rahul Bheke joins Mumbai City FC while Locatelli completes Juventus move.
Barcelona have been frighteningly good at home this season, scoring 15 goals in three games at the Nou Camp.
Paris Saint Germain's Neymar, Laywin Kurzawa and Leandro Paredes as well as Marseille's duo of Dario Benedetto and Jordan Amavi were given their marching orders after rival players threw punches and kicks at each other.
Dramatic finale as Valencia denied by 10-man Levante
Valencia forward Carlos Soler scored a hat-trick of penalties as his side beat La Liga champions Real Madrid 4-1 at home in an extraordinary match on Sunday.
Bayern Munich thrashed Bayer Leverkusen 5-1, while Barcelona came from behind to beat Valencia 3-1 in LaLiga at Camp Nou on Sunday.
Gareth Bale was once again subjected to whistling from a section of the Bernabeu crowd.
Real went top with one game to play after thrashing Atletico Madrid 4-0 while rivals Sociedad slipped to a 3-2 defeat at Celta Vigo.
A round-up of Saturday's action in Serie A, La Liga and Bundesliga.
Real Madrid paid homage to Cristiano Ronaldo as their outright leading scorer on Friday even though the official statistics show he has yet to overhaul former Spain striker Raul.
Unbeaten in six games, the draw leaves third-placed Sevilla on 51 points, four ahead of Real Sociedad and five ahead of both Getafe and Atletico Madrid, while Levante are 12th on 35 points.
A round of Saturday's matches in Series A, La Liga and Bundesliga.
Atletico Madrid took advantage of Barcelona's slip-up to go top of La Liga with a 4-0 victory over Real Sociedad as Real Madrid drew 1-1 at Athletic Bilbao and Cristiano Ronaldo was sent off on Sunday.
Federico Valverde has already made over 100 appearances at senior level - while winning silverware and recognition both with his current side Madrid and country Uruguay, and showing the physical, technical and mental attributes to become one of world football's outstanding midfielders.
Ajax, four-times European Cup winners who are in the knockout stages for the first time in 13 years, have enhanced their reputation as a talent factory due to the rise of homegrown Dutch players Frenkie de Jong and Matthijs de Ligt.
Holders Barcelona were drawn on Friday to play Real Sociedad in the quarter-finals of the King's Cup while Celta Vigo will take on Real Madrid.
Saul Niguez's second-half strike gave Atletico Madrid a 1-0 win at home to Las Palmas on Saturday, their first victory in four games in all competitions.
Iker Muniain gave Athletic a deserved lead in the 32nd minute by bundling the ball home after Real failed to get back in time to defend a counterattack.
Images from football matches played in the Italian Serie A and the La Liga on Friday.
News of all that transpired on and off the football field.
Real Madrid's hopes of overhauling La Liga leaders Barcelona suffered a stinging blow when they were held to a 2-2 draw at home to Valencia.
Manchester City's Premier League home match against Arsenal has been postponed because players from the London club have had contact with the owner of Greek side Olympiakos Piraeus, who has contracted the coronavirus. Meanwhile La Liga matches will be played without fans for at least the next two rounds of fixtures to try to stop the spread of the coronavirus, the Spanish league said.
Barcelona travel to newly-promoted Osasuna without their first choice front line.
Cristiano Ronaldo is eager to return to action as he prepares for his first start of the season when Real Madrid begin their Champions League defence on Wednesday against APOEL Nicosia, coach Zinedine Zidane said on Tuesday.
Images from soccer matches played across different leagues in Europe on Sunday
David Beckham earned the plaudits of his team mates, Fabio Capello and the Spanish media after he marked his return with a goal that helped Real Madrid to a 2-1 comeback victory at Real Sociedad on Saturday.
The former England captain scored on his return to the team after a month on the sidelines to inspire Real Madrid to a 2-1 comeback win at Real Sociedad.
Former Arsenal midfielder Mikel Arteta has joined ManchesterCity manager Pep Guardiola's coaching staff, the Premier League club said on Sunday.
Barcelona twice threw away the lead to draw 3-3 at Levante on Tuesday in a potentially fatal blow to their chances of winning the La Liga title.
The 35-year-old, who quit international football in 2014, took to Twitter, to reveal his decision.
La Liga's organising body announced on Monday that all clubs would begin testing their players this week as part of the first phase of a four-step protocol to return to playing matches, without spectators, in June.
'Barca are the best team around and when we play as we know how we are unstoppable'
Barcelona moved two points clear at the top of the table on Saturday after notching a 1-0 win at home to Real Sociedad while title challengers Sevilla beat Real Madrid 2-1.
The home side spurned two chances to extend their advantage before the break but Barca levelled in the 52nd minute when Luis Suarez glanced in Lionel Messi's free kick.