A little over six years after almost losing his life in a training-ground accident with the Ireland team, defender Shane Duffy will probably start one of the biggest games of his career against France in the second round of Euro 2016.
Leicester beat Southampton to open seven-point gap at the top.
It was a day of role reversal as Jose Mourinho's often cautious Chelsea thumped Everton 6-3 in a thriller on Saturday while champions Manchester City's attacking talents were blunted in a shock 1-0 home defeat by Stoke City.
Robert Huth's double and a Riyad Mahrez goal sent Premier League leaders Leicester City six points clear after a stunning 3-1 victory at shell-shocked title rivals Manchester City on Saturday.
Images from Saturday's action in the English Premier League.
Ashley Williams powered home a towering header in the 86th minute as Everton fought back to claim a 2-1 win over Arsenal as the title hopefuls blew the chance to return to the Premier League summit.
Here are five talking points from the weekend's Premier League action:
Liverpool a dramatic 2-1 victory over Leicester City at Anfield, thus maintaining the league leaders' 100 per cent start
Chelsea striker Diego Costa has denied he deliberately stamped on Liverpool's Emre Can.
The injury to the Chile forward, who was left out of the squad for Tuesday's Champions League victory over Young Boys, "will require further investigation to confirm its severity", the club added.
Images from the English Premier League matches played on Saturday.
Brief reports of English Premier League matches on Saturday:
Son fires Spurs to 2-0 win over Huddersfield
Images from the Euro 2020 qualifying matches played on Tuesday night.
Inter will be his sixth club in a career which began when he made his debut for Anderlecht as a 16-year-old and has taken him to Chelsea, West Bromwich Albion and Everton.
Spain strolled to a 4-1 win at home to Israel, while Italy survived some first-half scares on the way to a 2-0 win and Ukraine registered a 1-0 home win over Ukraine in an action-packed game.
Veteran Drogba showed that he still has a lot of steam in him as he scored in Chelsea's win over Spurs, while Aguero continued to top the goal-scorers' list this season, finding the net for City. Images from the EPL matches played across England on Wednesday.
Liverpool had to be satisfied with a 1-1 Premier League draw at Arsenal on Saturday as their usually prolific attacking trio were well shackled by their improving hosts.
Images from the English Premier League matches played at Old Trafford on Saturday
Chelsea heaped more Christmas misery on Liverpool with a 2-1 victory at Stamford Bridge and Olivier Giroud ended a seven-game scoring drought to help Arsenal win 1-0 at Newcastle United and return to the top of the Premier League on Sunday.
Manchester United ushered in a new era under interim manager Ryan Giggs with a 4-0 Premier League win over Norwich City on Saturday full of the verve and attacking intent often absent under the sacked David Moyes.
IMAGES from Saturday's English Premier League matches.
News of all that's transpired on and off the football field
Philippe Coutinho inspired Liverpool to a comfortable 3-1 home win over Everton in the 228th Merseyside derby on Saturday to move provisionally up to third in the Premier League.