Srikanth held a 4-1 record over Prannoy coming into this match, but the shuttler was unable to deliver. Srikanth won the first game 21-13, but Prannoy won the second set comprehensively.
Third seed Sindhu lost 17-21, 21-16, 18-21 to Zhang in another tough opening encounter that lasted 56 minutes.
India made a resounding start to their campaign at the Swiss Open Grand Prix Gold with four Indian shuttlers advancing to the second round of the men's singles competition, in Basel, on Wednesday.
Up against Shruti Mundada in the pre-quarters, Saina had a look at the surface and immediately made it clear that she won't risk playing on it given that the All England Championships are around the corner.
Top Indian shuttlers, Kidambi Srikanth and Parupalli Kashyap crossed the opening hurdle to reach the second round of men's singles competition at the $120,000 German Grand Prix Gold in Mulheim an der Ruhr in Germany on Tuesday.
P V Sindhu, K Srikanth, Ajay Jayaram, Subhankar Dey, B Sai Praneeth and Sameer Verma scored easy first round singles victories, while the pair of Jwala Gutta-Ashwini Ponnappa shocked a fancied Malaysian pair to enter the second round of the women's doubles.
Sindhu and Saina will once again be India's best bet as they look to put up a good show this week.
The World No 6 will next face Spain's Pablo Abian on Wednesday.
HS Prannoy started his campaign at the World Championship in style beating New Zealand's Abhinav Manota in straight games to enter the second round.
Kidambi Srikanth and two-time bronze medallist P V Sindhu will headline a 21-member Indian contingent as they gun for the elusive gold medal at the World Badminton Championships starting in Glasgow on Monday.
Commonwealth Games champion Parupalli Kashyap, Sameer Verma and the mixed doubles pair of Satwiksairaj Rankireddy and Ashwini Ponnappa notched thrilling victories to enter the quarter-finals of the India Open Super 500 World Tour badminton tournament in Delhi on Thursday.
Fourth seeded Srikanth, who had claimed a silver medal at this year's Commonwealth Games, had to dig deep in his reservoir to outwit fellow Indian H S Prannoy 18-21, 30-29, 21-18 in a thrilling match, clocking an hour and seven minutes.
Summary of sports events and persons who made news on Saturday
A quarterfinal loss at the All England Championship saw Indian shuttler Saina Nehwal slip three places down the rung to the sixth spot in the latest BWF world ranking on Thursday. Saina, who turned 26, went through injuries last year and missed out on a few tournaments this season, including the Syed Modi Grand Prix Gold and South Asian Games in January and February respectively. The Olympic bronze medallist, who had finished runners-up at the 2015 All England Championship, lost to Tai Tzu Ying in straight games in the quarterfinals. The Indian now has 73,222 points. Two-time bronze medallist at World Championship, P V Sindhu improved a place to reach the 11th spot.
Indian shuttlers Saina Nehwal, Kidambi Srikanth and Sameer Verma also advanced to the second round of the $550,000 tournament at the Barclaycard Arena.
Saina Nehwal breezed into the quarter-finals of the Denmark Open, scoring a 21-15, 21-17 victory over Japan's world No. 2-ramked Akane Yamaguchi on Thursday.
India ace Kidambi Srikanth was rewarded for his sensational run this season as he grabbed a career-best ranking of World No. 2 after jumping two places in the latest BWF ranking released on Thursday.
Kashyap, a Commonwealth Games champion, was trailing 8-14 in the third game when he chose to retire after pulling his calf muscle.
Sindhu, Sameer progress to quarters, Kashyap ousted
Sindhu, who had finished runners-up at the last edition in Dubai, will have a tough task at hand as she has been clubbed with defending champion Akane Yamaguchi of Japan, World No 1 Tai Tzu Ying of Chinese Taipei and USAs' Beiwen Zhang in Group A.
After six successive losses in 13 meetings, PV Sindhu finally got the better of her nemesis World No. 1 Tai Tzu Ying.
Sameer Verma stayed on course for his title defence while three-time former champion Saina Nehwal too reached the semifinals with an easy win
India's highest ranked male shutter, Kidambi Srikanth, pulled off an upset victory over former world No 1 Lee Chong Wei of Malaysia, but his team Bengaluru Hot Guns went down 2-3 to Hyderabad Hunters in the Premier Badminton League clash in Mumbai on Sunday.
Nehwal has had a troubled run in this year as she has now faced exits from a tournament in the first round five times.
Summary of sports events and persons who made news on Tuesday.
Indian shuttlers had a relatively good day in office at the Indonesia Open Super Series Premier badminton tournament in Jakarta on Wednesday, with the women's doubles pair of Jwala Gutta-Ashwini Ponnappa and the men's team of Manu Attri-B Sumeeth Reddy progressing to the second round.
Fifth seeded Sindhu, who made early exits from China and Korea last month, has been pitted against Michelle Li, who remains a tricky customer despite the fact that Sindhu has a 5-2 head-to-head record against the world no 9 Canadian.
Two-time champion and top seed Saina Nehwal and P V Sindhu reached the pre-quarterfinals of the $ 120,000 Swiss Open Grand Prix Gold in Basel.
Sindhu, who had won the silver at the World Championship last month, recovered from a mid-game slump to stave off the challenge from World No. 19 Minatsu Mitani of Japan 21-19, 16-21, 21-10 in a match that lasted 63 minutes.
H S Prannoy stunned the legendary Lin Dan of China while compatriot Sameer Verma pipped Rasmus Gemke of Denmark to advance to the second round of the Indonesia Open badminton event.
Saina, who was looking good at the start of the season, was diagnosed with acute gastroenteritis with mild pancreatitis which affected her performance at the All England Championship.
Indian ace shuttlers Kidambi Srikanth and Parupalli Kashyap advanced to the pre-quarterfinals after notching up contrasting victories in the men's singles competition of the $ 120,000 German Grand Prix Gold in Mulheim an der Ruhr.
Top Indian shuttlers, including K Srikanth and Parupalli Kashyap in men's singles and P V Sindhu in women's singles, advanced to the second round after easy victories on the first day of the main draw in the Syed Modi International Badminton tournament, in Lucknow, on Wednesday.
Top Indian shuttlers Saina Nehwal, P V Sindhu, K Srikanth and Parupalli Kashyap reached the second round of Syed Modi International Grand Prix Gold badminton tournament after scoring easy victories in Lucknow.
A summary of sports events and persons who made news on Saturday
Summary of sports events and persons who made news on Tuesday
Saina Nehwal and reigning champion Sameer Verma were a step away from clinching the men's and women's singles titles respectively
PV Sindhu will open her campaign against South Korea's Sung Ji Hyun, while Saina Nehwal takes on Scotland's Kristy Gilmour in the first round.
Olympic silver medallist P V Sindhu and National champion Sameer Verma began the new season on a resounding note by winning the women's and men's singles crowns respectively at the USD 120,000 Syed Modi Grand Prix Gold badminton tournament in Lucknow on Sunday.
Former India coach Anil Kumble is in the running for the Coach of the Year award in the inaugural edition of the Indian Sports Honours, instituted by the RP-SG Group in association with the foundation of skipper Virat Kohli.