Top seed Rafa Nadal, who has won the tournament 10 times, also reached the last eight after dispatching compatriot Guillermo Garcia-Lopez 6-1, 6-3 and claiming a record-extending 40th consecutive set on clay.
Real Madrid president Florentino Perez has ruled out an immediate return of the recently sacked Chelsea manager Jose Mourinho despite having `good memories` under the Portuguese's tenure in the club.
Luis Suarez, whose four-month ban for biting an opponent expires on Friday, will make his official Barcelona debut in Saturday's La Liga clasico at Real Madrid, coach Luis Enrique said.
Messi stretched Barca's lead by finishing off a brilliant move with Luis Suarez in the 50th minute and the Uruguayan joined his close friend and strike partner on 15 league goals by robbing an Eibar defender and finishing inside the near post in the 68th.
First Goa, now Gujarat!
Messi agreed no-fee Barca exit clause in case of Catalan independence
Spain snatched a 2-2 draw against Morocco on Monday to qualify for the World Cup last 16 and take top spot in Group B ahead of Portugal on goals scored.
Barca made a slow start to the campaign under their new coach but after beating Paris Saint Germain in the quarter-finals they are on course to repeat the treble success.
New Real Sociedad coach David Moyes faces a tough challenge to get the Basque club back on La Liga track but it is also a chance for the Scot to restore his reputation after a failed stint at Manchester United.
Former player and reserve team boss Santiago Solari has been put in caretaker charge after negotiations between the club and former Chelsea, Italy and Juventus boss Antonio Conte broke down on Monday, the club added.
Spain's right back Juanfran says his costly penalty shootout miss in Atletico Madrid's Champions League final defeat to Real Madrid has made him a better player at Euro 2016. Less than three weeks have passed since the veteran's spot kick hit the post and Cristiano Ronaldo converted the winning penalty for Real Madrid. Juanfran started in Spain's 1-0 victory over the Czech Republic in Group D on Monday and is expected to be in the line-up again when the champions take on Turkey on Friday.
"We are not going to deviate one iota from our footballing concepts," the distinguished former Spain defender Hierro said.
Barcelona forward Luis Suarez scored a hat-trick as his side thrashed arch-rivals Real Madrid 5-1 on Sunday in a highly entertaining 'Clasico' which surely will signal the end of hapless coach Julen Lopetegui's spell in charge of Real.
Real Madrid coach Jose Mourinho has been given a two-match ban for improper conduct by UEFA after allegations that two of his players deliberately got sent off in a Champions League match against Ajax Amsterdam.
The Frenchman, who won nine trophies in two-and-a-half years, suggested it is events off the pitch, rather than on it, that made him leave.
Barcelona forward Neymar has trained with the squad for the first time since injuring his ankle last month and is close to a return to action, the club said on Monday.
The result also means second-placed Real Sociedad can reclaim top spot if they beat Eibar on Sunday.
Twenty-three-times Cup winners Athletic Bilbao were dumped out in sensational circumstances by tiny island side SD Formentera, who sneaked a 1-0 win at San Mames with a header by Alvaro Muniz deep in stoppage-time to reach the last 16 for the first time with a 2-1 aggregate victory.
Real Madrid goalkeeper Iker Casillas has dismissed suggestions that the club's World Cup stars are on a collision course with new coach Jose Mourinho.
A bizarre last-minute goal from Mesut Ozil wrapped up a 3-1 comeback win for Real Madrid at home to city rivals Atletico Madrid on Thursday, giving them a healthy advantage in their King's Cup quarter-final.
With no Champions League football for a third straight season, the financial realities are starting to bite and Arsenal will be desperate for some of their talented youngsters to come through.
Barcelona's Luis Suarez netted twice for a 2-1 win over 10-man Atletico Madrid in their Champions League quarter-final, first leg on Tuesday after the visitors' Fernando Torres opened the scoring and was later sent off.
Champions Barcelona reclaimed top spot in La Liga on Sunday by overcoming a dogged Villarreal side to win 2-0 at home with goals from stalwart defender Gerard Pique and youngster Carles Alena taking them above Sevilla.
Barcelona followed up last weekend's 3-1 defeat at Real Madrid with another reverse on Saturday, squandering a host of chances to lose 1-0 at home to Celta Vigo and handing the lead in La Liga to their arch rivals.
And while the mercury hits its lowest, South Korea's Jang Hye-Ji launched the Games on Thursday by sliding the first mixed doubles curling stone in Olympic history down the ice, before about 2,500 spectators at Gangneung Curling Centre, AFP reported.
World No 2 Andy Murray overwhelmed Italy's Andreas Seppi 6-2, 7-5 and second seed Rafael Nadal crushed veteran Italian Paolo Lorenzi 6-1, 6-1 to reach the China Open second round on Tuesday.
Defending champion Andy Murray and ATP finals hopefuls Mikhail Youzhny and Fernando Verdasco all made surprise early exits from the Valencia Open on Wednesday. World number four and top seed Murray fell 6-2, 3-6, 6-2 to Argentine Juan Monaco in the second round, while world number 10 Youzhny pulled out at the start of the day with a back problem.
Cristiano Ronaldo scored twice as Real Madrid came from behind to beat Paris St Germain 3-1, while Sadio Mane grabbed a hat-trick as Liverpool demolished Porto 5-0 away in the Champions League round-of-16 on Wednesday.
Olympic silver medallist P V Sindhu yet again struggled to go past China's He Bingjiao and bowed out of the China Open World Tour Super 750, in Fozhou, on Friday.
The United States Tennis Association (USTA) said on Sunday it would undertake a review of its communication policies after a string of umpiring controversies at the U.S. Open.
There was no farewell goal but plenty of pride and appreciation as Wayne Rooney made his 120th and final appearance for England in a 3-0 win over the United States in a friendly at Wembley on Thursday.
Barcelona made a brisk start to the season with new coach Luis Enrique at the helm in place of Gerardo Martino and a host of additions to the squad, including midfielder Ivan Rakitic and goalkeeper Claudio Bravo.
Real Madrid secured a 10th European Cup when they snatched a stoppage-time equaliser before extra-time goals by Gareth Bale, Marcelo and Cristiano Ronaldo gave them a 4-1 win over Atletico Madrid in the Champions League final on Saturday.
Barcelona teenager Ansu Fati scored twice to lead his side to a 2-1 win at home to Levante on Sunday, finding the net in a league game for the first time in more than four months and becoming the youngest player to net a La Liga double. Romelu Lukaku scored a quickfire second-half double to give Inter Milan a 2-0 win at Udinese on Sunday, ending their run of three successive 1-1 league draws.
Here are five talking points from the weekend in La Liga:
Real Madrid defender Nacho was the unlikely hero as they snatched a 1-0 win at Real Valladolid on Sunday to capitalise on Barcelona's defeat at Valencia this weekend and move three points clear of their rivals at the top of La Liga. Serie A leaders Juventus suffered a shock 2-1 defeat at Napoli on Sunday, with coach Maurizio Sarri returning to his former club for the first time, though Cristiano Ronaldo still managed to score for an eighth league game in a row for the visitors.
He leads the men's seedings ahead of defending champ Roger Federer, with Bulgarian Grigor Dimitrov seeded third.
Two New York Police Department officers were shot and killed at point blank range in their patrol car in New York by a man who later shot himself at a nearby subway station, an attack described as an 'assassination'.
Real Madrid maintained their pursuit for the title by defeating Malaga 3-1 late on Saturday.
Centre-back Pique, who voted in the referendum and has criticised police violence against voters which resulted in hundreds of injuries, has long been targeted by Spain fans but Monday's barrage of insults was particularly severe.