Liverpool thrashed Atalanta 5-0, Real Madrid boosted their chances of reaching the Champions League knockout stages with a 3-2 home victory over Inter Milan and Bayern Munich came from behind to crush RB Salzburg 6-2.
Images from the English Premier League matches played on Wednesday
Mourinho's tinkerings meant a first start of the season for midfielder Scott McTominay, playing on the right of a three-man defence, while Anthony Martial played instead of the dropped Alexis Sanchez. On this evidence, more changes may be needed when United take on Valencia in the Champions League on Tuesday.
Europa League favourites Manchester United secured a 1-1 draw on a threadbare pitch at Rostov, while Olympique Lyonnais beat AS Roma 4-2 helped by a fine individual goal from Nabil Fekir in their last 16, first leg ties on Thursday.
Guardiola says City's points record may last years
Teenager Curtis Jones grabbed a 58th-minute winner as an injury-hit Liverpool qualified for the knockout stage of the Champions League with a 1-0 win over Ajax Amsterdam at Anfield on Tuesday.
Manchester City emerged from a trough of despair to beat Tottenham Hotspur 3-1 and move to within three points of the Premier League title at Wembley on Saturday.
News of all that's transpired on and off the football field
After falling 2-0 down on the night, substitute Marcos Llorente struck twice in extra-time and Alvaro Morata added a late third to ensure a famous victory for Diego Simeone's side against a Liverpool team unbeaten in their last 25 home games in European competition.
Summary of all that transpired on and off the football field
Real Madrid coach Zinedine Zidane reckons Cristiano Ronaldo is on top form as the Portuguese looks to increase his Champions League goals tally when they visit AS Roma in the first leg of their last-16 tie on Wednesday.
Premier League champions Chelsea eased past a disappointing Everton with goals from Spaniards Cesc Fabregas and Alvaro Morata sealing a 2-0 victory on Sunday.
Liverpool scored three goals in 12 dramatic first-half minutes, two of them from Emre Can, on their way to a hugely entertaining 4-2 win over Hoffenheim which took them back to the Champions League group stage after a two-season absence on Wednesday.
Liverpool were beaten 1-0 away to Atletico Madrid in their last-16 first leg on Tuesday.
Reports in British media put the latest bid at 125 million euros.
The win moved Spurs up to third but unbeaten Manchester City still looked in a class of their own at the top as Leroy Sane scored twice in a 4-0 stroll over West Ham United.
News of all that's transpired on and off the football field
Chelsea reached the Champions League knock-out stage on Tuesday despite a 1-0 defeat by Basel in Group E after a late Mohamed Salah goal shocked the 2012 title winners, with Jose Mourinho saying they deserved to lose. Barcelona, without Lionel Messi but already into the last 16, went two goals down in Amsterdam but looked a different side in the second half after Ajax's Joel Veltman was sent off.
Ibrahimovic was forced off with a muscle problem with 11 minutes remaining, and the Swede was pictured sitting on the bench with an ice pack strapped to the back of his left leg.
Edin Dzeko scored twice to set up a 3-1 win for AS Roma away to Napoli in the battle for second place in Serie A on Saturday and Paulo Dybala also notched up a brace for leaders Juventus in their 2-1 win over Udinese.
Huddersfield Town were left celebrating wildly after securing their Premier League safety on Wednesday with a dramatic and resilient 1-1 draw at Chelsea, a result that looks almost certain to condemn Swansea City to relegation.
Liverpool reached the Champions League final after riding their luck to contain a fired-up AS Roma in a 4-2 defeat at the Stadio Olimpico on Wednesday that sent them through 7-6 on aggregate.
Images from the EPL matches played on Sunday
Liverpool took over at the top of the Premier League table despite being held to a 0-0 draw against Manchester United in a scrappy match on Sunday.
Liverpool surrendered a two-goal lead as they were held to a 2-2 draw by third-tier Shrewsbury Town in the FA Cup fourth round on Sunday after second-half substitute Jason Cummins struck twice to inject some much-needed late magic into the competition. Earlier, Harry Maguire's thunderbolt for Manchester United started a goal rush at Tranmere where the Reds scored five times before halftime. Diogo Dalot, Jesse Lingard, Phil Jones, Anthony Martial and Mason Greenwood also scored.
Following is a match by match look at the English Premier League's weekend fixtures:
Images from the English Premier League matches played on Saturday
AS Roma supporters may be looking ahead to Barcelona's Champions League visit with some trepidation and coach Rudi Garcia certainly does not seem to be bursting with optimism.
Here are talking points from the weekend's Premier League action:
Liverpool came into Saturday's Champions League final against Real Madrid on a wave of confidence but Zinedine Zidane's side showed exactly why they are the masters of Europe's top club competition in their 3-1 win.
Manchester United climbed back up to second in the table after second-half goals by Anthony Martial and Jesse Lingard earned a 2-0 victory at Everton -- their first win in five games in all competitions.
News of all that's transpired on and off the football field
Manchester City set a new top-flight record of 15 consecutive wins as their seemingly unstoppable march towards the English Premier League title continued with a 4-0 romp at bottom club Swansea City.
Juergen Klopp refused to dwell on the two late goals they conceded in a 5-2 win over AS Roma in their Champions League semi-final, first leg on Tuesday, saying his team had been 'perfect' for 80 minutes.
Luka Modric pulled one back for Zinedine Zidane's shellshocked side with a brilliant strike from distance early in the second half before substitute Vinicius Jr reduced the deficit to one goal.
Images from the English Premier League matches played on Wednesday.
Images from the English Premier League matches played on Saturday
Champions Juventus returned to the top of Serie A with a 4-0 home rout of Cagliari on Wednesday, while former leaders Napoli dropped to second after being held to a goalless draw at Genoa.
Watford climbed into the top four of the Premier League after Tom Cleverley's 92nd-minute goal gave them a 2-1 victory over Arsenal at Vicarage Road on Saturday.
AS Roma's Daniele De Rossi celebrated his 500th appearance for the club with a goal in their 3-1 win over Empoli at the Olympic Stadium as they moved up to second place in Serie A on Saturday.
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