This is Anand's sixth loss to American in Classical chess and the Indian ace will now have to do a lot of hard work to catch up in the last five rounds.
With favourable results under his belt this year, five-time World champion Vishwanathan Anand is approaching the forthcoming World Chess Championship at Sochi with a quiet confidence and a positive frame of mind but termed his opponent Magnus Carlsen as "tenacious".
Five-time world champion Viswanathan Anand took a decisive step towards his second big title of the year after drawing with Ruslan Ponomariov of Ukraine in the fifth and penultimate round of the Final Masters.
Grandmaster S P Sethuraman continued with his dream run and played out a fighting draw with higher ranked Anish Giri of Holland in the first game of the third round of World Chess Cup in Tbilisi, Georgia.
Summary of sports events and persons who made news on Monday
India's Viswanathan Anand regained the sole lead with a sparkling victory over former challenger Veselin Topalov from Bulgaria in the ninth round of Candidates Chess tournament in Khanty Mansiysk on Sunday.
Five-time world champion Viswanathan Anand celebrated the Indian World Cup victory with a crushing win against Levon Aronian of Armenia in the second round of Zurich Chess Challenge.
Wesley So of the United States expectedly won the tournament with an easy draw with white pieces against Maxime Vachier-Lagrave of France in the final round.
Five-time world champion Viswanathan Anand played out a draw with Vladimir Kramnik in the fourth round but remained in sole lead to stay in contention in the Candidates chess tournament in Khanty Mansiysk.
Vishy Anand face world champion Magnus Carlsen for the first time in India since his 2013 World Championship defeat in Chennai, during the Tata Steel Rapid and Blitz tournament to be held in Kolkata from November 22 to 26.
Five-time World champion Viswanathan Anand began his campaign in the Zurich Chess Challenge on a losing note, beaten by Armenia's Levon Aronian in the first round.
Five-time world champion Viswanathan Anand won two, lost two and drew one for a joint third place finish at the blitz tournament of Zurich Chess Classic.
Five-time World champion Viswanathan Anand suffered a shocking defeat at the hands of Canadian Grandmaster Anton Kovalyov to leave the Indian on the verge of an early exit at the FIDE Chess World Cup in Tbilisi, Georgia.
Indian chess ace Viswanathan Anand will find himself in the unfamiliar position of starting as the lowest-ranked player when he takes on a tough field in his first Classical tournament since losing the world title, in the Zurich Challenge in Zurich at the Savoy.
A summary of sports events and persons who made news on Thursday
Rameshbabu Praggnanandhaa is just 13 years old but the boy is already going places and this was his second win against a 2700 Grandmaster.
Five-times world champion Viswanathan Anand proved all his critics wrong and won the Candidates Chess tournament after settling for a draw with Sergey Karjakin of Russia in the 13th and penultimate round in Khanty Mansiysk (Russia) on Saturday.
Viswanathan Anand's woes in the Grenke Chess Classic continued as the five times world champion blundered yet again and went down to Levon Aornian of Armenia in the fifth round that concluded in Baden-Baden in Germany.
Grandmaster and former Asian champion S P Sethuraman has knocked out former FIDE champion Ruslan Ponomariov of Ukraine in a big first round upset at the Chess World Cup in Tbilisi, Georgia.
Grandmaster and former national champion B Adhiban beat Brazilian Grandmaster Alexander Fier in the second round and advance to the third round of the chess World Cup in Tromso, Norway, on Thursday
Five-time world champion Viswanathan Anand started his campaign at the Bilbao Final Masters with a crushing win over former FIDE world champion Ruslan Ponomariov of Ukraine in Bilbao, Spain.
Five-time world champion Viswanathan Anand sealed the Candidates tournament title with an effortless draw with Peter Svidler of Russia in the 14th and final round in Khanty Mansiysk.
Five-time world champion Viswanathan Anand inched closer to clinching the Candidates Chess tournament title after settling for an easy draw as black against Vladimir Kramnik of Russia in the 11th round in Khanty Mansiysk.
Summary of sports events and persons who made news on Thursday
Former FIFA official Jerome Champagne formally announced on Monday that he will stand against incumbent Sepp Blatter in next year's election for president of the world soccer body.
A summary of sports events and sports persons, who made news on Friday.