Lionel Messi scored in his 12th consecutive La Liga game to help leaders Barcelona earn a 1-1 draw at Valencia, allowing second-placed Atletico Madrid to close to within nine points after a 1-0 win over Real Betis on Sunday.
Here are five talking points from the weekend in La Liga.
Alvaro Negredo struck in stoppage-time as stuttering Valencia won 2-1 against his former club Sevilla on Sunday to earn coach Pako Ayesteran victory in his first home game in charge since succeeding Gary Neville.
Real Madrid and Barcelona pulled two points clear in La Liga when Cristiano Ronaldo set a club scoring record in Real's 3-0 stroll against Levante and Neymar hit four as Barca beat Rayo Vallecano 5-2 on Saturday.
Leaders Barcelona kept up their relentless pace at the top of La Liga with a 4-0 thrashing of city rivals Espanyol and 10-man Real Madrid needed two goals from Cristiano Ronaldo to see off Real Sociedad 4-3 on Sunday.
Nine Catalan separatist leaders were jailed for between nine and 13 years on Monday for their roles in an illegal referendum and subsequent failed independence bid, sparking protests and clashes across the region. Barcelona is the capital of Catalonia.
Champions Barcelona reclaimed top spot in La Liga on Sunday by overcoming a dogged Villarreal side to win 2-0 at home with goals from stalwart defender Gerard Pique and youngster Carles Alena taking them above Sevilla.
Lionel Messi netted his first hat-trick in 10 months as Barcelona swept aside struggling Granada 4-0 to climb above Atletico Madrid to the top of La Liga on Saturday.
Barcelona equalled the La Liga record for the most points after 10 games and moved three clear of Atletico Madrid at the top of the table thanks to a 3-1 win at home to Celta Vigo on Saturday.
Marcelino dismissed but Valencia keep pressure on Barcelona
Barca lead the standings on 39 points from 18 games, three clear of second-placed Real Madrid who host Athletic Bilbao on Sunday.
Barcelona's attacking trio of Lionel Messi, Luis Suarez and Neymar were all on target as the champions roared back into life in La Liga with a dominant 5-1 victory at promoted Leganes on Saturday. Messi sidefooted in a simple cross from Suarez to strike the opening goal after 15 minutes and returned the favour for the Uruguayan to nudge in the second in the 31st.
Cristiano Ronaldo became the first player to hit 30 La Liga goals in six consecutive seasons as he inspired Real Madrid to a 4-0 thrashing of Eibar on Saturday.
A summary of Saturday's action in the LaLiga, Serie A and Bundesliga.
Barcelona's 100 per cent start to the season was ended by Catalonian neighbours Girona, who picked up a draw at the Nou Camp, allowing Real Madrid to take advantage with a victory over Espanyol.
Lionel Messi squeezed home a stoppage-time penalty to grab a 3-2 win for champions Barcelona at Valencia in a thrilling and controversial La Liga match on Sunday.
Cristiano Ronaldo took his league tally for the season to 30 as leaders Real Madrid swept aside Espanyol 5-0 at the Bernabeu to restore their 10-point advantage over Barcelona in La Liga on Sunday.
'We have to improve and become stronger in defence, which is the most important thing.'
Barcelona rode their luck to come from behind and win 2-1 at Real Sociedad on Saturday, continuing to banish their awful record in San Sebastian and maintaining their perfect start to the La Liga season.
Real were left with 10 men before halftime when Mbappe saw a straight red after taking down Alaves midfielder Antonio Blanco as the referee overturned his initial decision of booking him with a yellow after consulting with VAR.
Images from Sunday's action in LaLiga and Serie A.
Sevilla missed a chance to get their La Liga campaign up and running when the Europa League holders surrendered the lead and were held to a 1-1 draw at Levante on Friday.
Pepe opened the scoring for Real with a looping header that flew past Jan Oblak in the 52nd minute and it looked like the hosts would earn three points to move five clear of Barcelona at the top of La Liga.
Griezmann goal earns Atletico first win of season
Barcelona kept Real Madrid's La Liga title celebrations on hold for a few days at least with a crushing 7-0 victory at Rayo Vallecano on Sunday after Real had cruised to a 3-0 home win over Sevilla.
Cristiano Ronaldo struck his 43rd league goal of the campaign to set Real Madrid on their way to a 3-0 home win over Sevilla on Sunday that put them within a whisker of a first La Liga title in four years.
Lionel Messi scored within three minutes of returning to action for the first time in more than three weeks to help fire La Liga champions Barcelona to a resounding 4-0 home win over Deportivo La Coruna on Saturday.
Sevilla's hopes of a place in European competition next season suffered a big blow when they let slip a one-goal lead to lose 5-1 at Getafe in La Liga on Monday.
Cristiano Ronaldo and Lionel Messi took their remarkable scoring achievements to new heights when they jointly set a record for La Liga goals in a season of 41 on Saturday.
Barcelona trimmed the gap to leaders Real Madrid to three points when Lionel Messi struck twice in a 4-1 comeback win at relegation-threatened 10-man Real Zaragoza in La Liga on Saturday.
Real Madrid's stuttering run continued as they were held 1-1 at home by La Liga minnows Eibar on Sunday, drawing a fourth consecutive game in all competitions for the first time in more than a decade.
Luis Suarez played a part in all three of Barcelona's goals in a scrappy 3-1 victory at Granada.
The win increased Zinedine Zidane's side's advantage at the top of the standings to six points
'Messi is a player that makes a difference in all games and in Clasicos he has always made a big impact but we will have to see if he is ready' 'You never know what can happen in these types of games and when you start as favourite it can often go wrong'
Lionel Messi scored four as Barcelona came from behind to thrash Valencia 5-1 at home, closing the gap on La Liga leaders Real Madrid back to 10 points on Sunday.
Lionel Messi broke a Spanish hat-trick record and Luis Suarez struck twice as a rampant Barcelona took over top spot in La Liga with a 6-1 hammering of Rayo Vallecano on Sunday.
Zinedine Zidane's side joined Atletico Madrid on 66 points and moved top of the table
Athletic Bilbao's bid for a berth in next season's Europa League stuttered when they lost 2-1 at Espanyol on Monday.
Vinicius Jr's remarkable performances at Real Madrid have put the 24-year-old forward as the odds-on favourite to claim his first Ballon d'Or when the award for the best player in the world is announced in Paris on Monday.
Real Madrid moved seven points clear at the top of La Liga with a comfortable 3-1 win over bottom side Real Zaragoza as Barcelona could only draw 0-0 at lowly Villarreal on Saturday.