Real Madrid's Thibaut Courtois, Federico Valverde, Eduardo Camavinga and Vinicius Jr have tested positive for COVID-19.
Spain were Nations League runners-up two years ago to France and success will come as a major fillip after a disappointing World Cup in Qatar, where they were upset by Morocco in the last-16.
A summary of the opening day's action in the UEFA Champions league on Tuesday.
PSG's Champions League tie with Newcastle is like a final, says Luis Enrique
Barcelona won their 27th LaLiga title and first for four years after a 4-2 win at city rivals Espanyol on Sunday.
A round-up of Wednesday's action in the UEFA Champions League
Barcelona started strongly, with Gavi stinging the palms of Espanyol goalkeeper Alvaro Fernandez in the sixth minute, shortly before Alonso glanced a header into the net, following a corner.
Atletico Madrid have recorded five COVID-19 positives, including manager Diego Simeone
Roundup of Champions League matches played on Wednesday night
Morocco are happy to sit back and look to punish opponents on the counter-attack using the speed and skill of Hakim Ziyech
IMAGES from the FIFA World Cup Group E match played between Spain and Japan on Thursday.
Germany's players, however, must not only process their first ever loss to Japan, they are also under fire back home for their handling of a diversity armband affair
Harry Kane scored twice in his first league appearance in front of a home crowd to steer champions Bayern Munich to a 3-1 victory over Augsburg.
Spain and Costa Rica are playing in Group E along with Germany and Japan.
Barcelona fought back to earn a 2-2 draw with Manchester United in a pulsating Europa League knockout round playoff first leg on Thursday.
Karim Benzema and Vinicius Jr both scored a brace to give the LaLiga leaders a 4-1 home win over Valencia
Barcelona extended their LaLiga lead to eight points thanks to second-half goals by Jordi Alba, Gavi and Raphinha that gave them a 3-0 home win against Sevilla
The UNICEF is the world's largest single vaccine buyer, procuring more than 2 billion doses of various vaccines annually for routine immunisation and outbreak response on behalf of nearly 100 countries.
The win moved Barcelona up to fourth place on 38 points from 22 games
Gavi, 18, and Pedri, who turned 20 during the tournament, showed maturity beyond their years at the heart of the team's midfield, while strikers Ansu Fati and Nico Williams, both 20, looked full of potential when they came off the bench.
Atletico celebrate anniversary with 3-1 comeback win over Mallorca
IMAGES from the UEFA Nations League matches played on Sunday.
According to the WHO, countries should join the COVID-19 Vaccine Global Access Facility (COVAX Facility) by September 18 but not later than October 9 with upfront payments.
However, before the Moderna and Pfizer messenger ribonucleic acid (or mRNA) vaccines come to India via this route, the legalities around the indemnity clause will have to be settled, reports Sohini Das.
By January-February, it's expected to have at least 100 million doses for the Indian government, reports Sohini Das.
Images from the international friendly and Euro qualifying football matches played on Tuesday.
Real Madrid's France forward Karim Benzema won the 2022 Ballon d'Or award for the best men's player in the world on Monday, while Barcelona's Spain midfielder Alexia Putellas won the women's award for a second time.
IMAGES from the El Clasico match played at Estadio Santiago Bernabeu in Madrid on Sunday.
It was Spain's first competitive win in Portugal since 1934
Leaders Barcelona played out a second straight 0-0 draw in LaLiga after mid-table Getafe battled for a home point in a hard-fought game on Sunday.
Union Berlin's Paul Jaeckel scored a 76th-minute winner to give his team a 1-0 victory at VfB Stuttgart on Sunday and send them two points clear at the top of the Bundesliga.
Images from the Nations League matches played on Thursday.
World Health Organisation (WHO) chief Tedros Adhanom Ghebreyesus on Wednesday thanked Union Health Minister Mansukh Mandaviya for announcing resumption of COVID-19 vaccine shipments to the COVAX global pool in October.
Ferran Torres scored a brace and Ousmane Dembele made two assists as a red-hot Barcelona rolled over Osasuna 4-0 on Sunday to earn their fourth consecutive LaLiga win.
COVAX, 'the global COVID vaccine equity scheme', has so far delivered 65 million doses to 124 countries and economies but it is dependent on countries and manufacturers honouring their commitments.
India will resume export of surplus COVID-19 vaccines next month under the 'Vaccine Maitri' programme and to meet its commitment to the COVAX global pool, but vaccinating its own citizens remains the topmost priority of the government, health minister Mansukh Mandaviya said.
The 'terrible' surge of the coronavirus cases in India has severely impacted COVAX's vaccine supply in the second quarter of this year to the extent that there will be a shortfall of 190 million doses by the end of June, according to a joint statement by the WHO, UNICEF, GAVI and CEPI.
A model being considered is to have a combined cold chain approach - where the agricultural cold chain would be combined with vaccine cold chains.
This is an important milestone that paves the way for bringing the company's single-dose COVID-19 vaccine to the people of India, and the rest of the world, through a collaboration with Biological E Limited, the statement added.