Real Madrid's stuttering season continued as they were reduced to 10 men and then slumped to an 11th La Liga defeat of the campaign by going down 3-1 at Real Sociedad.
Last season's treble winners Barca are in their worst run of form in La Liga since coach Luis Enrique took charge in August 2014.
Moffi penalty gives Lorient 1-0 win over Monaco.
On a seismic day in the history of Chelsea, Romelu Lukaku scored the winning goal in a 3-2 FA Cup fifth-round victory
Real went top with one game to play after thrashing Atletico Madrid 4-0 while rivals Sociedad slipped to a 3-2 defeat at Celta Vigo.
When Barca and Neymar were at the peak of their powers in 2017, however, he shook world football by heading to PSG for a record-smashing 222 million euros ($269.89 million).
Spain are still favourites to finish top of Group E above Sweden, Poland and Slovakia but, after struggling to break down conservative sides such as Georgia and Greece in March, they know coming first will not be a procession.
Gareth Bale was once again subjected to whistling from a section of the Bernabeu crowd.
The Argentine then lifted his shirt to reveal a red and black replica kit of his hometown club Newell's Old Boys bearing the number 10 which Maradona wore during his brief spell at the Rosario side in 1993.
La Liga leaders Barcelona earned a narrow 1-0 win over Real Valladolid to move seven points clear at the top, while Real Madrid lost 2-1 at home against Girona to fall to third behind Atletico Madrid.
Barcelona have been frighteningly good at home this season, scoring 15 goals in three games at the Nou Camp.
A summary of Thursday's matches in the Europa League.
Atletico Madrid took advantage of Barcelona's slip-up to go top of La Liga with a 4-0 victory over Real Sociedad as Real Madrid drew 1-1 at Athletic Bilbao and Cristiano Ronaldo was sent off on Sunday.
Real Madrid paid homage to Cristiano Ronaldo as their outright leading scorer on Friday even though the official statistics show he has yet to overhaul former Spain striker Raul.
IMAGES from the English Premier League matches played on Saturday.
With no fans allowed into venues and Real playing their home games at the 6,000-capacity Alfredo Di Stefano stadium while the Santiago Bernabeu is being refurbished, it will be a title race unlike any other.
London sides Tottenham Hotspur and Arsenal made winning starts as did fellow Premier League club Leicester City.
The draw interrupted a run of four straight league wins for Zinedine Zidane's side and left them second on 67 points after 31 games, three behind leaders Atletico who thrashed Eibar 5-0 earlier in the day.
Saul Niguez's second-half strike gave Atletico Madrid a 1-0 win at home to Las Palmas on Saturday, their first victory in four games in all competitions.
Holders Barcelona were drawn on Friday to play Real Sociedad in the quarter-finals of the King's Cup while Celta Vigo will take on Real Madrid.
David Beckham earned the plaudits of his team mates, Fabio Capello and the Spanish media after he marked his return with a goal that helped Real Madrid to a 2-1 comeback victory at Real Sociedad on Saturday.
The former England captain scored on his return to the team after a month on the sidelines to inspire Real Madrid to a 2-1 comeback win at Real Sociedad.
Real Madrid's hopes of overhauling La Liga leaders Barcelona suffered a stinging blow when they were held to a 2-2 draw at home to Valencia.
Dramatic finale as Valencia denied by 10-man Levante
Paris Saint Germain's Neymar, Laywin Kurzawa and Leandro Paredes as well as Marseille's duo of Dario Benedetto and Jordan Amavi were given their marching orders after rival players threw punches and kicks at each other.
Ajax, four-times European Cup winners who are in the knockout stages for the first time in 13 years, have enhanced their reputation as a talent factory due to the rise of homegrown Dutch players Frenkie de Jong and Matthijs de Ligt.
Barcelona moved two points clear at the top of the table on Saturday after notching a 1-0 win at home to Real Sociedad while title challengers Sevilla beat Real Madrid 2-1.
Iker Muniain gave Athletic a deserved lead in the 32nd minute by bundling the ball home after Real failed to get back in time to defend a counterattack.
A round of Saturday's matches in Series A, La Liga and Bundesliga.
Valencia forward Carlos Soler scored a hat-trick of penalties as his side beat La Liga champions Real Madrid 4-1 at home in an extraordinary match on Sunday.
Real Madrid failed to keep the pressure on leaders Barcelona as they were held to a draw by relegation-threatened Real Sociedad.
Cristiano Ronaldo is eager to return to action as he prepares for his first start of the season when Real Madrid begin their Champions League defence on Wednesday against APOEL Nicosia, coach Zinedine Zidane said on Tuesday.
Former Arsenal midfielder Mikel Arteta has joined ManchesterCity manager Pep Guardiola's coaching staff, the Premier League club said on Sunday.
Unbeaten in six games, the draw leaves third-placed Sevilla on 51 points, four ahead of Real Sociedad and five ahead of both Getafe and Atletico Madrid, while Levante are 12th on 35 points.
'Barca are the best team around and when we play as we know how we are unstoppable'
Zinedine Zidane has had a three-month ban for coaching Real Madrid's B team without the correct licence overturned on appeal, the club confirmed on Friday.
The 35-year-old, who quit international football in 2014, took to Twitter, to reveal his decision.
Among other transfer news globally, defender Rahul Bheke joins Mumbai City FC while Locatelli completes Juventus move.
Real fought back after a calamitous own goal from keeper Keylor Navas gave Betis the lead in the 25th minute, just after the Costa Rican escaped a possible red card. Cristiano Ronaldo pulled the hosts level in the 41st with a diving header.
