Spain international striker Alvaro Negredo became ManchesterCity's third major signing of the close-season when he completed his move from Sevilla to the Premier League club on Friday.
Roma have taken just four points from their last five league matches, and were eliminated from the Coppa Italia last week in a 1-0 defeat to rivals Lazio.
Cristiano Ronaldo grabbed a hat-trick and Gareth Bale became the fifth British player to score for Real Madrid at the Bernabeu in La Liga when he struck twice in an action-packed 7-3 win over Sevilla on Wednesday.
Goalkeeper Andres Palop emerged as Sevilla's hero by saving three penalties in the shootout to give his side victory over Espanyol.
Atletico Madrid surrendered top spot in La Liga to Barcelona when they were held to a 0-0 draw at home to 10-man Sevilla in a fiercely contested La Liga clash on Sunday.
Sevilla maintained their brilliant record at home in Europe with a 2-1 win over Steaua Bucharest in the Champions League.
It is not the first time the midfielder has received a reprieve after initially being banned for picking up a fifth yellow card.
All the action from football matches played in Europe on Wednesday
Spain striker Fernando Llorente scored in Athletic Bilbao's 2-1 La Liga victory over struggling Real Zaragoza on Sunday to continue his prolific recent run.
Middlesbrough scored four times in an hour to beat Steaua Bucharest 4-2 to reach the UEFA Cup final for the first time
Lionel Messi scored twice as La Liga champions Barcelona saw off a persistent Valencia side, who had Eliaquim Mangala sent off in the first half, to win 4-2 on Sunday and stay on the heels of leaders Real Madrid.
Eric Abidal crowned a superb defensive display with a rare goal to help Barcelona to a 1-1 draw at Athletic Bilbao on Wednesday and put the La Liga leaders through to the quarter-finals of the King's Cup on away goals.
IMAGES from the Champions League matches played on Tuesday
IMAGES from football matches played across European leagues on Saturday
Atletico Madrid stayed hot on the heels of second-placed city neighbours Real Madrid when Radamel Falcao netted his 25th goal of the La Liga campaign in a scrappy 1-0 win at mid-table Sevilla on Sunday.
Holders Sevilla maintained their Europa League challenge with a 1-0 win over Rijeka in a winner-takes-all clash on Thursday.
Manchester United goalkeeper David de Gea added another heart-stopping save to his collection as his team held a highly-impressive Sevilla side to a 0-0 draw away from home in the first leg of their Champions League last-16 tie on Wednesday.
The Copa del Rey semi-final draw will be made on Friday.
Sevilla, who reached the last 16 of the Champions League last season, were handed a shock playoff defeat by unfashionable Braga on Tuesday while Werder Bremen pulled off a spectacular escape act to oust Sampdoria.
Sevilla stayed firmly on course for a second consecutive Europa League crown when an Aleix Vidal double and a Kevin Gameiro strike secured a thumping 3-0 win at home to Fiorentina in their semi-final first leg on Thursday.
Sevilla claimed their second King's Cup triumph in four years when Diego Capel's early strike and a late breakaway goal from Jesus Navas fired them to a 2-0 win over Atletico Madrid on Wednesday.
Lionel Messi netted two late goals as champions Barcelona thrashed Sevilla 4-0 on Saturday to stretch their advantage over second-placed Real Madrid at the top of La Liga to five points.
Espanyol secured a commanding lead in their King's Cup quarter-final tie against Sevilla when Felipe Caicedo, Sergio Garcia, with a penalty, and Lucas Vazquez scored in a 3-1 first-leg home win on Thursday.
Organisers trial virtual crowd noise option
Real Madrid manager Carlo Ancelotti said on Saturday he is happy with how new signing Kylian Mbappe is settling into life with the Spanish soccer giants and he has no concerns about his team's slow start to the LaLiga season.
Frederic Kanoute's emphatic finish early in the first half fired Sevilla to a 1-0 win at Sporting Gijon in La Liga on Sunday to lift the Andalusians above Valencia into third.
News of all that's transpired on and off the football field
Real Madrid suffered a shock 2-1 defeat by Sevilla in La Liga on Sunday as winger Jesus Navas and midfielder Renato stuck with headers in each half.
Sevilla's La Liga match at home to Levante was briefly suspended on Saturday when fans threw scores of tennis balls onto the pitch in protest over the kick-off time.
Spain manager Luis de la Fuente left Barcelona's 17-year-old defender Pau Cubarsi and midfielders Marcos Llorente and Aleix Garcia out of his 26-man squad
All the action from La Liga and Serie A matches played on Monday
Arsenal, who top Group H by a point from Sevilla and have yet to concede a goal in Europe this season, overpowered the Andalucians 3-0 when they met at the Emirates stadium in September.
Real Madrid beat Sevilla 3-1 at the Bernabeu to move six points clear at the top of the Primera Liga.
Barcelona lost more ground in the title race on Sunday with a 0-0 draw at Osasuna while Sevilla showed they are the Primera Liga's form team with a 4-1 stroll past regional rivals Recreativo Huelva.
News of all that's transpired on and off the football field
Sevilla's Kevin Gameiro grabbed a late equaliser in a 2-2 draw at Zenit St Petersburg on Thursday to send the Europa League holders into the semi-finals after woeful goalkeeping had threatened to ruin their night.
Holders Sevilla led the charge into the last four of the King's Cup when Renato's early strike set them on their way to a 3-0 home win over Villarreal on Tuesday.
Jose Mourinho has been charged with using abusive language against a match official, governing body UEFA said
Dani Alves faces charges of sexual assault of a woman in a Barcelona nightclub last December.