The 36-year-old has been practising hard on the grass and few would bet against her becoming the first mother to win the title since Evonne Cawley 38 years ago.
Two-times Grand Slam champion Naomi Osaka advanced to the US Open final for the second time in her career with a 7-6(1), 3-6, 6-3 victory over big-hitting Jennifer Brady.
Separated in age by 25 years, their careers overlapped only briefly and Martina Navratilova, who herself won 18 Grand Slam singles crowns, never faced Serena Williams on a singles court.
Tennis star Serena Williams says she is concerned about the Zika outbreak ahead of August's Rio Olympics, but has faith in the support team dealing with worries about the mosquito-carried virus.
Serena Williams did not need the help of a fan-filled Arthur Ashe Stadium to provide a lift during her 7-5, 6-4 win over the 96th ranked Kristie Ahn.
Seven-time champion Williams had been bidding to claim a record-equalling 24th Grand Slam crown but made too many errors as Kerber ran out a comfortable winner in the final.
Serena Williams had to dig deep to fend off Latvian challenger Jelena Ostapenko as she wrapped up Friday's play at the Fed Cup in Seattle with a hard-fought victory that gave the United States a 2-0 advantage. Williams' experience and savvy ways showed in critical moments against the 22-year-old Ostapenko as she prevailed 7-6(4), 7-6(3) in a match that took one hour and 46 minutes.
Serena Williams clinched a record 23rd grand slam title at the Australian Open on Saturday but spent most of the immediate aftermath talking about her older sister Venus.
The exodus of seeded players has been so spectacular that only one of the top 10 remains -- number seven Karolina Pliskova.
Serena Williams is skipping practice on the eve of the French Open final as the World No 1 battles with illness, organisers said on Friday.
Halep finds groove to reach Prague semi-finals.
Once a simmering volcano of emotions that could erupt at any moment, Australian Open champion Serena Williams appears to be heading down a path that may perhaps lead to her being renamed Serene.
American tennis star Serena Williams rose early on Saturday to get ready for her friend Meghan Markle's wedding to Britain's Prince Harry with a gold face treatment mask and personal make-up artist.
Coco Gauff claimed the biggest win of her young career on Friday with a stunning upset of defending champion Naomi Osaka at the Australian Open to reach the fourth round. Caroline Wozniacki and Serena Williams also lost their respective matches earlier in the day. Images from Day 5 of the Australian Open played at Melbourne Park on Friday.
Holder Serena Williams beat Justine Henin 6-2, 6-0 to reach the semi-finals of the Sony Ericsson Open.
Former world number one Serena Williams has pulled out of the French Open because she has not fully recovered from health issues, organisers said on Thursday.
McEnroe had claimed that Serena, who is the best player of her gender, would be ranked 700 if she plays on the men's circuit.
US Open champion Naomi Osaka grew up dreaming of competing against Serena Williams in a Grand Slam final but never would have dared to go as far as to think her idol would be reduced to tears in a drama-filled match.
The World No 1 Serena was joined by Hollywood actress Eva Longoria at a Champ'Seed party in Monaco.
Serena Williams fuelled talk of a dream-team partnership with home favourite Andy Murray after declaring her availability for the Wimbledon mixed doubles.
Twenty-three time grand slam champion Serena Williams will play her first match since the birth of her daughter when she faces off against French Open winner Jelena Ostapenko at the Mubadala World Tennis Championship in Abu Dhabi next week.
Tennis player Serena Williams was recently spotted getting cozy with rapper Drake at a fancy downtown restaurant in Ohio.
Daniil Medvedev and Karen Khachanov crushed second seed Dominic Thiem and third seed Alexander Zverev respectively to set up an all-Russian semi-final at the Rogers Cup in Montreal on Friday.
Serena Williams has clicked into gear so quickly on her Wimbledon return it is hard to believe she has played only a handful of matches
Germany's experienced Angelique Kerber stands in the way of the 36-year-old American and an eighth, and arguably most impressive, All England Club singles crown which would see her match Margaret Court's all-time record of 24 Grand Slam titles.
Images from the US Open women's singles second round matches, at Flushing Meadows, New York, on Thursday.
Ohanian and Williams sisters taking up golf with TGL ownership
Tennis great Serena Williams on Wednesday said she would consider coaching after calling it quits.
Serena Williams plans to play fewer tournaments in the future to aid her quest to win more Grand Slam titles, according to her coach Patrick Mouratoglou.
It will be the 22nd career match-up between the two long-time rivals, who somehow have avoided each other at the US Open throughout their long careers.
The duo hailed each other in the post-match interview before the tennis titans captured the iconic moment in what Hopman Cup on Twitter described as the 'greatest selfie of all time'.
Naomi Osaka faces a far more daunting task: Playing against her hero in the US Open final.
Steamrolls Dutch Rus to proceed to Round 2
Serena Williams likened the frustration she felt in Tuesday's shock defeat by Maria Sakkari at the Western and Southern Open to that of being stuck in a bad relationship.
Halep has struggled for form and fitness since her first-round defeat at the US Open last August and came to Australia on a five-match losing streak and without a coach after long-serving Darren Cahill left for "family reasons".
Serena Williams recently faced a social media criticism after she posted a photoshopped picture of herself.
Serena Williams was forced to go on the attack once again to defend equal prize money after she reached a ninth Wimbledon final in a new record time. The world number one blasted Russia's Elena Vesnina off Centre Court in just 48mins 34sec, the fastest ever semi-final at the All England Club. Vesnina earned 500,000 ($649,000) by making the last four.
Serena Williams is unlikely to win a record equalling 24th Grand slam title on the claycourts of Roland Garros, although her chance will come, the American's long-time coach Patrick Mouratoglou said on Friday.
The new Da da ding Nike ad, featuring actor Deepika Padukone, has gone viral. It has been appreciated by most but panned by some, and despite the mixed reviews it has nearly crashed the internet.