Two Robin van Persie goals earned the Gunners a 2-1 victory as Chelsea slid to a second home league defeat of the season.
Ahead of their high-profile clash on Saturday, check out the five standout clashes between Arsenal and Chelsea.
Second-half goals from Klaas-Jan Huntelaar and Robin van Persie gave Netherlands a 2-0 triumph over Romania on Tuesday, wrecking their hopes of qualifying for the Euro 2008 quarter-finals. Huntelaar sidefooted home in the 54th minute from a right-wing cross by Ibrahim Afellay and Van Persie made sure of victory with a fierce left-foot drive in the 87th after expertly controlling a free kick by Demy de Zeeuw.
Chelsea's Jose Mourinho and his old friend Louis van Gaal of Manchester United had different reasons to be satisfied with a point after their teams drew 1-1 in the Premier League at Old Trafford on Sunday.
Late goals by Robin van Persie and Thierry Henry gave Arsenal a thrilling 2-1 win over Manchester United on Sunday, shattering the visitors' bid to open a nine-point lead in the Premier League.
Arsenal's Dutch international forward Robin van Persie was arrested earlier this month on suspicion of rape.
News of all that's transpired on and off the football field
Robin van Persie and Wayne Rooney were on target as Manchester United secured a 2-0 home win over 10-man CrystalPalace on Saturday with a workmanlike display that will have done little to worry their Premier League title rivals.
Irish female footballer Stephanie Roche, who currently plays for French division 1 Feminine club ASPTT Albi, has earned a unique distinction of being the only woman to have been shortlisted for FIFA's goal of the year alongside fellow strikers Robin van Persie and James Rodriguez.
The difference in fortunes since Liverpool won 3-0 away to Manchester United in March was illustrated when Louis Van Gaal's team reversed that scoreline on Sunday.
Images from the EPL match played between Manchester United and Southampton on Monday.
Jose Mourinho shared the honours with former mentor Louis van Gaal as his Chelsea side drew at Manchester United in the Premier league on Sunday, but there was no doubt which of the pair was happier with the 1-1 result.
How could a front six including Angel Di Maria, Robin van Persie, Wayne Rooney and Juan Mata fail to get a single shot on target in a 1-0 home defeat by Southmapton?
Manchester United's footballers and their wives and girlfriends have a blast at this year's Christmas party.
We have witnessed lots of drama, excitement and goals from the first half of the football World Cup. Rediff gives you a flashback of the best moments from the World Cup.
From a crazy race track crash to Robin van Persie's record for The Netherlands, to Mario Balotelli obliging some female fans, Rediff.com has all that and more snapped right here.
After switching to a new-look formation that sparkled against Queens Park Rangers last weekend, a diamond may just be Louis van Gaal's new best friend as the Manchester United boss looks set to continue with it against Leicester City on Sunday.
Unlike some young football players of his generation, Barcelona superstar Lionel Messi is a complete family man.
Danny Welbeck and Jesse Lingard both scored twice as English champions Manchester United got their first win of the David Moyes era with a 5-1 victory over an A-League All Stars team at the Olympic Stadium on Saturday.
'Every player needs that moment, that turning point ... to settle and hopefully now Arsenal can see what they paid for... 72 million pounds was seeming expensive until tonight'
Champions Manchester United rediscovered a touch of their old swagger to beat West Bromwich Albion 3-0 on Saturday and record back-to-back Premier League wins for the first time since December.
Manchester United kept their season alive by reaching the Champions League quarter-finals with a memorable victory over Olympiakos Piraeus on Wednesday, but under-pressure manager David Moyes was not getting too carried away.
Photos of the third-place playoff match between Brazil and Netherlands
In the buildup to the World Cup, the Brazilian football catchphrase of 'Jogo Bonito' -- The Beautiful Game -- was drowned out by the bangs of frantic construction work and the shouts of angry protesters.
Fans favourite punching bag, manager David Moyes, had it again, this time on twitter when the fans vented out their anger for not including Juan Mata.
If the past is any guide, we should be in for something memorable on Wednesday in Sao Paulo when the Netherlands meet Argentina in the World Cup semi-final at the Corinthians arena.
The suspension of captain Robin van Persie for Monday's World Cup Group B decider against Chile means the Netherlands will play an international without a player whose surname begins with 'Van' for the first time in almost two decades.
An injury-time goal from Fulham's Darren Bent inflicted more pain on champions Manchester United as the bottom club rescued a 2-2 Premier League draw on Sunday, adding fuel to the fire for manager David Moyes's critics.
Spain playmaker Juan Mata will bring flair and crowd-pleasing skills when he completes his move to Manchester United but the ailing Premier League champions need more than that to resurrect their season.
Manchester United returned to winning ways after three straight defeats with a 2-0 Premier League home victory over Swansea City on Saturday, avenging last week's FA Cup loss to the Welsh club.
Wayne Rooney has briefly escaped Manchester United's winter of discontent and has been sent to warmer climes to recover from a groin injury, manager David Moyes said on Friday.
Manchester United's past and future collided as debutant James Wilson scored twice in a 3-1 win over Hull City on Tuesday that marked the end of stalwart Nemanja Vidic's Old Trafford career and set tongues wagging about Ryan Giggs.
Alex Ferguson was a keen promoter of home-grown talent but his incredible collection of silverware would not have been possible without some stunning transfer coups for Manchester United. Here are some of the best and worst Ferguson signings.
Manchester United captain Nemanja Vidic has a chance of making his return from injury against Sunderland at Old Trafford on Saturday, manager Alex Ferguson said.
Everton manager Roberto Martinez believes criticism of his side by Arsenal's Arsene Wenger should be seen as a compliment but he is keen to avoid complacency seeping into his squad ahead of Saturday's home game against Fulham.
Liverpool's Luis Suarez will be the greatest player not to win one of England's player of the year awards if he is overlooked this season, according to his captain Steven Gerrard.
Wayne Rooney will be desperate to vent his frustration on Chelsea in Sunday's FA Cup quarter-final following his controversial omission from the Manchester United team to play Real Madrid this week.
Amid transfer confusion, wife, Coleen Rooney is pleading hubby Wayne not to move abroad.