The Frenchman nodded home an Isco cross after 55 minutes against a well-organised Granada side that attacked with pace.
Casillas had suffered a heart attack during a training session last year and has not played any competitive football since April, 2019.
The local government, meanwhile, is deploying more than 200 national police officers to prevent crowds assembling, with mayor Jose Luis Martinez-Almeida also asking people to stay away.
Rafael Nadal has issued a rallying cry and called on Spanish athletes to help raise 11 million euros ($12.07 million) to help fight the coronavirus pandemic. Spain is one of the most badly affected countries in the world with over 56,000 cases and the parliament voted to extend the coronavirus lockdown to at least April 12 after the death toll rose to over 4,000 by Thursday.
Karim Benzema and Vinicius Jr both scored a brace to give the LaLiga leaders a 4-1 home win over Valencia
Real coach Zinedine Zidane left out Cristiano Ronaldo and Gareth Bale in a largely second-string side but not even the injection of youth could breathe life into his team until Asensio's late goal ended a run of three games without a win.
The World and European champions close out their centenary celebrations with a match against a FIFA World Selection, featuring many of the best players on the planet, on Wednesday.
Real Madrid star striker Cristiano Ronaldo scored thrice to help his side thrash Espanyol 6-0 in a ruthless attacking display in La Liga clash at Santiago Bernabeu.
The season kick backs into action with a local derby between Sevilla and Real Betis on June 11 and there will be fixtures for the following seven days, with Barca hosting Leganes on June 16
Pierre-Emerick Aubameyang scored twice as a rejuvenated Barcelona gave a football masterclass to inflict a humiliating 4-0 defeat on rivals Real Madrid on Sunday.
Constantine interviewed by Chennaiyin FC
Union Berlin's Paul Jaeckel scored a 76th-minute winner to give his team a 1-0 victory at VfB Stuttgart on Sunday and send them two points clear at the top of the Bundesliga.
Until this season Manchester City's progression in the Champions League could be measured in baby steps but on Tuesday they can make a huge leap forward when they host Real Madrid in their first European semi-final for 45 years.
Teenage Norway midfielder Martin Odegaard became Real Madrid's youngest La Liga debutant at the age of 16 when he came on as a substitute in the 58th minute of Saturday's final game of the season at home to Getafe.
Barcelona were hailed as La Liga champions-elect in the Catalan media after their 1-0 win at Real Madrid on Saturday, while the capital's press called for sweeping changes at Real after another domestic failure.
The suspension of soccer leagues across Europe due to the COVID-19 pandemic will see overall player value drop by 6.6 billion euros ($7.5 billion), or about 18%, in the transfer market, KPMG's global head of sports Andrea Sartori said. The majority of leagues have resumed or are in the process of restarting their seasons behind closed doors before the transfer window reopens, with clubs still reeling from the financial impact of the months-long shutdown.
Real Madrid superstar Cristiano Ronaldo had reportedly 'taunted' Barcelona ace Lionel Messi after he won the Ballon d'Or by parading the trophy before Madrid's match against Granada, before firing a message as to who is the best around.
River Plate battled back to beat arch Argentine rivals Boca Juniors 3-1 in extra-time in an unforgettable and unique Copa Libertadores final second leg, played in Madrid after violence had seen the original game postponed.
Bringing you all the news from the summer transfer window and other snippets from the soccer world...
Real and Barca have won the title in 15 of the last 16 seasons, with Atletico breaking the duopoly in 2014.
Jeswin Aldrin, who had already qualified for the championships, however missed the cut.
That was also Messi's 500th goal for Barcelona.
The old format was skewed in favour of the bigger clubs, who could rest players for a first leg and swallow defeat before calling on their stars to turn the tie around in the return game.
The Portuguese forward put his team on the verge of their third final in four years and took his tally to 103 goals in the competition as he helped Madrid vanquish their neighbours at the Santiago Bernabeu.
Barcelona's rescheduled La Liga game at home to Real Madrid is set to take place on December 18 as both clubs came to an agreement after the match, due to be played on October 26, was postponed amid violent political demonstrations in Catalonia.
Cristiano Ronaldo celebrated his recent Ballon d'Or award by scoring twice for the first time in a La Liga game this season as champions Real Madrid swept to a stunning 5-0 win over Sevilla on Saturday to go five points behind leaders Barcelona.
Chelsea have signed Spanish goalkeeper Kepa Arrizabalaga for a world record 80 million-euro ($92.8 million) fee from Athletic Bilbao, the Premier League club said on Wednesday.
Real Madrid will not seek to boost their squad ahead of their transfer ban, which starts at the end of the month, club president Florentino Perez said on Wednesday. Perez's leadership at Real has been synonymous with glamour signings but the club will be unable to register new players during the next two transfer windows for breaching FIFA rules on signing non-Spanish Under-18 players. "We will not sign players during the winter market but this has nothing to do with the punishment. It is because we have the best players and the best trainer," Perez told France Football.
Barcelona blew the La Liga title race wide open when Lionel Messi scored a hat-trick in a 4-3 comeback win for the champions at 10-man Real Madrid in an action-packed 'Clasico' on Sunday.
News of all that's transpired on and off the football field.
Federico Valverde has already made over 100 appearances at senior level - while winning silverware and recognition both with his current side Madrid and country Uruguay, and showing the physical, technical and mental attributes to become one of world football's outstanding midfielders.
There was eye-catching sports action the world over and we summarise it all in this breathtaking photo feature...
The Modric family took refuge in a hotel near Zadar in 1991 when the war that followed the breakup of former Yugoslavia started and after Luka's grandfather was killed by Serb militia.
Real Madrid have exonerated Argentina winger Angel Di Maria over an incident in Monday's La Liga game at home to Celta Vigo when he was caught on camera grabbing his crotch while being substituted.
Brazilian Malcom, who started in place of Lionel Messi, curled home in the 58th minute to pull Barcelona level after Lucas Vazquez had fired Real Madrid ahead early on.
Zidane is currently in charge of Real's B team Castilla, and has for some time been linked with the manager's post.
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