Inter Milan face Barcelona, Tottenham Hotspur and PSV Eindhoven in Group B which features three former European champions.
IMAGES from Europa League matches played on Thursday.
Bayern's Mazraoui suffers heart complications due to COVID
In the third-tier Europa Conference League, English Premier League club Leicester City will face Danish side Randers and Scottish club Celtic will take on Norwegian champions Bodo/Glimt in the knockout playoff round.
The three Premier League and three La Liga clubs in the last eight avoided each other, with Manchester City up against Atletico Madrid and Liverpool to face Portuguese side Benfica.
'We appreciate your support all over the world'
The FIFA 2022 World Cup will kick-off in Qatar on Sunday, November 20. Here is a list of the 26-man squads playing in the quadrennial global football extravaganza.
Atletico Madrid celebrated like they had won the trophy after reaching the Champions League quarter-finals by edging past PSV Eindhoven 8-7 on penalties on Tuesday following 210 goalless minutes in their last-16 tie.
The defender later became the club's assistant coach before embarking on an eventful career as a head coach, managing Dutch sides Ajax Amsterdam, PSV Eindhoven and Feyenoord plus Premier League sides Southampton and Everton and La Liga's Valencia.
An air of familiarity will pervade the Champions League return of PSV Eindhoven and Manchester United when they open their Group B campaign in the Netherlands on Tuesday.
Paris St Germain revived their Champions League campaign with a 2-1 win over Liverpool in Group C on Wednesday, leaving the English club's hopes of reaching the last 16 hanging in the balance.
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A summary of Thursday's matches in the Europa League.
Arsenal's inability to kill off the contest will be a frustration as that has been a hallmark of their recent form. They had won their previous 18 Premier League matches in which they scored first.
Dutchman Ronald Koeman has signed a two-year-deal with Barcelona.
Seven-time European champions AC Milan hit back from two goals down against Celtic to claim a 4-2 victory that sent them into the Europa League knockout phase on Thursday as they were among 14 teams to progress in Europe's second-tier competition.
Action from Europa League matches played on Thursday.
A summary of Tuesday night's matches in the UEFA champions League.
Barcelona have been frighteningly good at home this season, scoring 15 goals in three games at the Nou Camp.
Manchester United winger Memphis Depay is keen to breathe fresh life into his faltering career in England under new manager Jose Mourinho after enduring a disappointing debut campaign under former boss Louis van Gaal.
The 30-year-old joins Luke Shaw in the treatment room after the left back pulled out of the England squad with an injury on Monday.
Napoli kept alive their hopes of advancing from Group C after Lorenzo Insigne, Victor Osimhen and Matteo Politano secured a 3-0 home win over Legia Warsaw.
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A summary of Thursday night's UEFA Champions League matches.
The 32-year-old, who captained the Dutch to third place at the 2014 World Cup in Brazil, has been overlooked by coach Danny Blind, who is not convinced about his form with Fenerbahce.
Ajax Amsterdam registered a 4-1 win at De Graafschap, their first title since 2014 and a record-extending 34th overall completed the double after they won the KNVB Cup earlier this month.
In England, the celebrations went on at Leicester City as they marked their fairytale Premier League success with another win while champions Juventus' long unbeaten streak in Italy came to an end.
Dick Advocaat will quit as Russia coach and has agreed to join PSV Eindhoven after Euro 2012, the Dutchman said on Monday.
Manchester United forward Memphis Depay is unhappy at being relegated to a bit-part role under new manager Jose Mourinho and has demanded more playing time after failing to start a Premier League game this season. The 22-year-old has dropped down the pecking order behind Anthony Martial, Marcus Rashford, Juan Mata and Jesse Lingard at Old Trafford, making just three appearances from the bench in the current league campaign.
Manchester United's Luke Shaw is set to undergo a second operation on Friday after breaking his right leg in two places in Tuesday's 2-1 loss to PSV Eindhoven, according to British media reports.
News of all that's transpired on and off the football field.
Manchester United, Sevilla and Celtic led a parade of clubs with continental pedigree to book the first places in this season's Europa League knockout stage.
Harry Kane netted his 200th goal for Tottenham Hotspur as they won 3-1 at Ludogorets and AC Milan's 24-match unbeaten run ended
Images from action in the Europa League matches on Thursday.
Summary of sports events and persons who made news on Thursday
Lionel Messi, Luis Suarez and Neymar combined to devastating effect as Barcelona swatted Celtic aside 7-0 at the Nou Camp to lay down a marker in Champions League Group C on Tuesday.
Holders FC Barcelona have been placed in Group E, along with Bayer Leverkusen, AS Roma, Dinamo Zagreb.
The 25-year-old, who joined PSV from Partizan Belgrade in 2000, was top scorer with 31 goals in the Dutch first division last season.
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