Liverpool's first loss of the season means they cannot finish the campaign unbeaten to match Arsenal's 'Invincibles' of 2003-04.
England head into Euro 2020 with a new factor for manager Gareth Southgate to deal with -- high expectations.
IMAGES from the Premier League matches played on Saturday
Two late goals by Everton substitutes brought the Merseysiders a third successive win when they beat Crystal Palace 2-0 at Goodison Park in Sunday's only Premier League game.
A rejuvenated Manchester United claimed a sixth win from six matches since former striker Ole Gunnar Solskjaer stepped in following the sacking of Jose Mourinho.
Should Manchester United win their next two games, the gap will be cut to four points and while only a collapse of astonishing proportions would deny Manchester City the title.
Images from Saturday's action in the Premier League.
IMAGES from EPL matches played on Thursday.
Manchester City moved 17 points clear of the pack with a 3-0 win at Fulham on Saturday
Chelsea have topped the spending list with Manchester United not far behind, but West Ham United's business epitomises the TV riches which give all Premier League clubs spending power that only the elite teams in Spain or Germany can dream of.
Roberto Firmino scored twice as Liverpool boosted their hopes of Champions League football next season
Chelsea, Manchester City and Manchester United enjoyed comfortable wins in the English Premier League on Saturday as fans returned to stadiums after an eight-month absence.
Manchester United remain winless at home in the league this season after Arsenal enjoyed their first win at Old Trafford
Four-times winners Germany enjoyed a 3-0 win over Group J rivals Iceland
Bayern Munich wasted a two-goal lead and needed a lucky 82nd- minute winner from Joshua Kimmich to beat Borussia Dortmund 3-2 in Germany's Super Cup on Wednesday and secure their fifth title of the year.
New Everton boss Sean Dyche's reign began with a shock 1-0 victory over English Premier League leaders Arsenal.
Everton have 36 points from 26 games
IMAGES from the EPL matches played on Saturday.
Liverpool's Trent Alexander-Arnold scored with a spectacular strike as they overcame the loss of three players to suspected positive COVID-19 tests and conceding an early goal to beat Newcastle United 3-1 in the Premier League on Thursday.
Bruno Fernandes struck from the penalty spot in the ninth minute of stoppage time to give Manchester United victory at Brighton & Hove Albion in the Premier League on Saturday after an incredible finale.
Diogo Jota and Mohamed Salah were on target as Liverpool edged Premier League strugglers Nottingham Forest 3-2.
Everton's Abdoulaye Doucoure scored an extra-time winner as they edged Rotherham United 2-1 in an absorbing FA Cup
IMAGES from the Premier League matches played on Saturday.
'Yes, I was sure this was the right decision. We brought Roberto Firmino on for Mo Salah. We could have scored before, we could have scored afterwards, we could have scored all the time. We lived more or less in their box'
England created numerous chances but Calvert-Lewin's penalty was the only addition to the score as the hosts impressed ahead of Nations League clashes against Belgium and Iceland.
Champions Manchester City have won their last 10 home league matches scoring a total of 36 goals.
Liam Delap, the son of former Stoke City defender Rory, scored the opener for Pep Guardiola's side in the 2-1 win at the Etihad Stadium
A round-up of Sunday's action in the Premier League.
Rodriguez whipped Everton in front from the edge of the box, and Michael Keane and Calvert-Lewin ensured it was two wins from two in the Premier League so far this season.
The hosts had looked on course to take all three points from a drab match when Anthony Knockaert pounced on a loose ball and fired home eight minutes from full-time.
Liverpool regained their place at the top of the English Premier League with a 2-0 win at Cardiff City on Sunday that restored their two-point lead over Manchester City
A round-up of Saturday's action in the Premier League.
Images from Saturday's action in the English Premier League.
Leicester City won at Arsenal for the first time in 47 years on Sunday, with substitute Jamie Vardy's late close-range header enough to secure victory in the Premier League at The Emirates.
Liverpool survived a late spell of Everton pressure to stretch their record unbeaten run in Merseyside derbies to 17 games
Manchester City secured a record 15th straight victory in all competitions with a 3-1 win at Championship side Swansea City in the FA Cup fifth round on Wednesday.
It promises to be a tense and thrilling finale to the season but Liverpool, who have frittered away a seven-point lead, will need to regain their momentum quickly if they are to push for their first league title since 1990.
Chelsea took a major step towards the Premier League title with an impressive 3-0 win over Everton at Goodison Park on Sunday.
IMAGES from soccer matches played in the English Premier League and the La Liga on Monday.