Guardiola said City had plenty of options, with Gabriel Jesus the only main striker fit and ready but Ilkay Gundogan and Raheem Sterling are able to slot into the role.
Liverpool started the ball rolling with a convincing 4-1 win at home to promoted Norwich and City responded a day later with an even more emphatic 5-0 victory at West Ham United.
Liverpool head to United with widest gulf in years
In an effort to show equality and inclusiveness towards people of all races and sexual orientation, players, officials from the English Premier League and even the historic Wembley Stadium was decked in the colours of the rainbow.
Premier League champions Chelsea eased past a disappointing Everton with goals from Spaniards Cesc Fabregas and Alvaro Morata sealing a 2-0 victory on Sunday.
A preview of the line-up action in the English Premier League.
Substitute Jesse Lingard struck twice in the second half as Manchester United fought back from 2-0 down to earn a 2-2 Premier League draw with Burnley at Old Trafford on Tuesday.
Images from Saturday's Premier League matches.
Manchester United have scored 14 goals and earned maximum points from their four matches under interim boss Ole Gunnar Solskjaer.
Jose Mourinho tried to conceal his obvious anger at the incidents which he clearly believed had cost Premier League leaders Chelsea victory over Burnley on Saturday.
Arsenal must trust in Arteta, says Guardiola.
Sunderland striker Jermain Defoe was recalled to the England squad at the age of 34 on Thursday ahead of next week's friendly in Germany and a World Cup qualifier at home to Lithuania.
Images from the English Premier League matches played on Saturday.
Should Manchester United win their next two games, the gap will be cut to four points and while only a collapse of astonishing proportions would deny Manchester City the title.
The two previous meetings at Anfield ended in 4-0 and 3-1 defeats for Arsene Wenger's Arsenal teams, but there is a fresh optimism around the club after a successful transfer window.
Cavani suspended by FA for three games over use of racial term
Images from Saturday's action in the Premier League.
Manchester City squandered a gilt-edged opportunity to close the gap on Premier League leaders Chelsea when they let slip a two-goal lead to draw 2-2 at home to struggling Burnley on Sunday.
Images from the English Premier League matches played on Sunday
Arsene Wenger suggested on Sunday that once relieved of his duties as Arsenal manager in a week's time he could think about life as a fan of the London club he served for 22 years - and have fun shouting at his successor.
News of all that's transpired on and off the football field.
IMAGES from the EPL matches played on Saturday
Following is a match by match look at the English Premier League's weekend fixtures:
Manchester United climbed back up to second in the table after second-half goals by Anthony Martial and Jesse Lingard earned a 2-0 victory at Everton -- their first win in five games in all competitions.
Match-by-match facts and statistics ahead of the Premier League
Images from the League Cup matches played on Tuesday
Manchester City's Pep Guardiola was named Manager of the Year at a League Managers Association awards ceremony on Tuesday after leading his side to the Premier League title and a host of records.
Striker Zlatan Ibrahimovic has terminated his contract with Manchester United with immediate effect, the Premier League club said in a statement on Thursday.
Like Chelsea, the humble Hertfordshire club, whose only season in European football was 35 years ago, completed their third victory from three games on Sunday, when they beat Crystal Palace 2-1 to add to victories over Brighton and Burnley.
United down Newcastle after Saints stun Chelsea on a dramatic night in the English Premier League.
Jack Wilshere and Harry Kane have been recalled to the England squad for Friday's World Cup qualifier against Scotland and a friendly against Spain, the FA announced on Sunday.
In just a few months at Old Trafford, Jose Mourinho has been dismissed from the touchline and fined for his conduct as his side endured a poor start to the season -- yet the Portuguese is still enjoying being Manchester United manager.
Raheem Sterling scored a second-half hat-trick as leaders Manchester City beat Watford 3-1 on Saturday while Liverpool kept the gap at one point by overcoming Burnley 4-2 on Sunday.
Leicester City's traumatic week ended with a 1-0 win at Cardiff City although the result was never the chief concern on a day when the tributes flowed for the Midlands club's late owner Vichai Srivaddhanaprabha who died in a helicopter crash.
Harry Kane's 101st Premier League goal was the difference as Tottenham Hotspur earned a 1-0 win over Arsenal, to continue their fine recent form in north London derbies in front of a Premier League record crowd at Wembley on Saturday.
Sergio Aguero scored a hat-trick as free-scoring Manchester City climbed to the top of the Premier League with an irresistible 6-0 victory against Watford on Saturday.
News of all that's transpired on and off the football field
Chelsea's 0-0 home draw with second-placed United ensured Thomas Tuchel is still undefeated in nine games since replacing Frank Lampard, but it meant they failed to dislodge fourth-placed West Ham United who became Manchester City's 20th successive victims in all competitions on Saturday.
Mauricio Pochettino's Tottenham Hotspur can cement their status as the top dogs in the capital if they end an eight-year wait and defeat Arsenal in the North London derby on Sunday.
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