Thomas Mueller scored twice as Bundesliga leaders Bayern Munich came from a goal down to beat Hanover 3-1 on Saturday and stretch their advantage at the top to 11 points after VfL Wolfsburg slumped to a 1-0 loss at Augsburg.
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Departing Bayern Munich coach Pep Guardiola has been assured a bittersweet farewell at the German club with the pending celebration of a record fourth straight Bundesliga title soured by another failure to shine on the European stage.
Leaders Bayern Munich eased past VfB Stuttgart 2-0 on Saturday to grab their first win of the year, as did Borussia Dortmund who beat Freiburg 3-0 to climb off the bottom of the Bundesliga table.
Despite their first-leg advantage, Pochettino warned against complacency and said he wanted his team to play for another win, although they have had one day less to prepare than the Germans.
Bayern Munich's party was wrecked by Borussia Moenchengladbach who hit back for a 1-1 draw at the Allianz Arena on Saturday, forcing the Bavarians to wait at least a week to clinch a fourth straight Bundesliga title.
Villarreal's Adrian Lopez produced a stinging sucker punch in stoppage time to leave Liverpool reeling and move the Spaniards closer to a maiden European final after their Europa League last four first leg clash finished 1-0 on Thursday.
Real Madrid are determined to create an intimidating atmosphere for visitors VfL Wolfsburg as they try to overturn a two-goal deficit in Tuesday's Champions League quarter-final second leg at the Santiago Bernabeu stadium.
Dele Alli condemned Champions League holders Real Madrid to a horrendous Wembley debut with two goals as Tottenham Hotspur reached the last 16 with a stunning 3-1 victory.
Barcelona have been haunted by their recent failures in the Champions League and there are concerning signs for the Catalans as they prepare for Tuesday's last-16 first leg away to Olympique Lyonnais.
IMAGES from the English Premier League matches played on Sunday
'So, the Champions League final will be played between two teams who just don't know when they are beaten,' says Suhit K Sen.
Harry Kane was hailed as 'unbelievable' after the England striker's 21st and 22nd goals of the season inspired Tottenham Hotspur to a routine win at hapless Aston Villa on Sunday that boosted their Premier League title ambitions.
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The Bavarians have now won the German league title a record 29 times.
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Manchester United manager Louis van Gaal will delve into the depths of his squad for the visit to Arsenal in the Premier League on Saturday, as an injury crisis engulfs Old Trafford.
Barcelona's Lionel Messi and Luis Suarez secured victory over nine-man Atletico Madrid in La Liga's top of the table clash, while Juventus won a 12th straight Serie A game to stay hot on the heels of leaders Napoli.
London clubs' erratic start to the Premier League season improved with victories for Chelsea, Tottenham Hotspur and Arsenal on Saturday but Manchester sides continued to make the running, with City and United the top two.
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An in-form Bayern Munich will be looking to notch up their fourth straight win in the Champions League group stage and seal a spot in the final 16 when the Bundesliga champions face Viktoria Plzen on Tuesday.
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Napoli rediscovered their scoring touch as they brushed aside Inter Milan 3-0 on Friday, sending their opponents' new coach Stefano Pioli back to the drawing-board.
Two late moments of Lionel Messi magic and a goal from Neymar helped Barcelona break the resistance of Bayern Munich in a pulsating 3-0 victory in their Champions League semi-final first leg at the Nou Camp on Wednesday.
The South American trio of Lionel Messi, Neymar and Luis Suarez reached a scorching 108 goals for the season following the La Liga leaders' 8-0 destruction of Cordoba on Saturday but the team's defence is yet to dispel doubts
In-form Borussia Moenchengladbach struck three times in 14 minutes in the second half to floor champions Bayern Munich 3-1 on Saturday and inflict their first Bundesliga defeat of the season.
Injury-ravaged Bayern Munich beat Hoffenheim 2-0 on Saturday, shrugging off a string of absences and their midweek Champions League defeat at Porto to close in on the Bundesliga title.
United are 16th in the standings with a game in hand heading into the international break.
AS Roma's Daniele De Rossi celebrated his 500th appearance for the club with a goal in their 3-1 win over Empoli at the Olympic Stadium as they moved up to second place in Serie A on Saturday.
Spain coach Luis Enrique said football had been unfair to his side after Thursday's dramatic 3-2 defeat in Croatia left them in danger of failing to reach the UEFA Nations League finals.
Cristiano Ronaldo renewed his personal battle with Lionel Messi by scoring his 71st Champions League goal, putting him three behind the Argentine's newly-set record, in Real Madrid's 1-0 win at FC Basel on Wednesday.
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Substitute Sergio Araujo struck a late equaliser as Las Palmas held Real Madrid to a 2-2 draw and left them with a one-point lead over Barcelona at the top of La Liga on Saturday.
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Bundesliga champions Bayern Munich suffered their first league defeat in 18 months when they slumped to a 1-0 loss at Augsburg on Saturday as Sascha Moelder's first-half strike ended their record 53-game unbeaten league run.
Hoffenheim ended champions Bayern Munich's 19-game winning streak in the Bundesliga on Saturday with a 3-3 draw after first taking the lead and then fighting back from two goals down.
Bayern Munich, already crowned Bundesliga champions last week, lifted the league trophy in an empty stadium on Saturday after crushing hosts VfL Wolfsburg 4-0 on the final matchday. Bayern can win more silverware next week with the German Cup final against Bayer Leverkusen. They are also still in the Champions League.
Rediff.com brings you the top highlights of the soccer weekend.
Romelu Lukaku scored twice to earn Belgium a 2-1 victory over Switzerland in the Nations League on Friday, lifting the mood in the country after a week marred by match-fixing allegations.